Peripheral CD4CD8 Double Positive T Cells with a Distinct Helper Cytokine Profile Are Increased in Rheumatoid Arthritis

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

(2013) Daniel Mucida et al.   NATURE IMMUNOLOGY

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4+ T cell immunity

(2013) Bernardo Sgarbi Reis et al.   NATURE IMMUNOLOGY

Characterization of Effector Memory CD8+ T Cells in the Synovial Fluid of Rheumatoid Arthritis

(2012) Bon-A Cho et al.   JOURNAL OF CLINICAL IMMUNOLOGY

CD4+CD8+ T Cells Represent a Significant Portion of the Anti-HIV T Cell Response to Acute HIV Infection

(2012) M. A. Frahm et al.   JOURNAL OF IMMUNOLOGY

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

Association of anticytomegalovirus seropositivity with more severe joint destruction and more frequent joint surgery in rheumatoid arthritis

(2011) Matthias Pierer et al.   ARTHRITIS AND RHEUMATISM

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments

(2011) Heleen Scheerens et al.   ARTHRITIS RESEARCH & THERAPY

Anticytokine therapy impacting on B cells in autoimmune diseases

(2010) Capucine Daridon et al.   CURRENT OPINION IN RHEUMATOLOGY

Abatacept for Rheumatoid Arthritis: A Cochrane Systematic Review

(2010) L. J. MAXWELL et al.   JOURNAL OF RHEUMATOLOGY

Double Positive CD4CD8 αβ T Cells: A New Tumor-Reactive Population in Human Melanomas

(2010) Juliette Desfrançois et al.   PLoS One

Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4+ T Cells

(2010) J. J. O'Shea et al.   SCIENCE

Different roles for anti-cyclic citrullinated peptide antibodies and CD4+CD28nullcells in the acceleration of atherosclerosis in rheumatoid arthritis: Comment on the article by Farragher et al

(2009) Roberto Gerli et al.   ARTHRITIS AND RHEUMATISM

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

B-cell-directed therapies for autoimmune disease

(2009) Thomas Dörner et al.   Nature Reviews Rheumatology

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE