Single-Cell Transcriptomics Reveal Disrupted Kidney Filter Cell-Cell Interactions after Early and Selective Podocyte Injury

Integrative single-cell analysis

(2019) Tim Stuart et al.   NATURE REVIEWS GENETICS

The role of the BMP4/Smad1 signaling pathway in mesangial cell proliferation: A possible mechanism of diabetic nephropathy

(2019) Cheng Chen et al.   LIFE SCIENCES

Class-3 Semaphorins and Their Receptors: Potent Multifunctional Modulators of Tumor Progression

(2019) Shira Toledano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

(2019) Paul T. Brinkkoetter et al.   Cell Reports

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

(2019) Rany M. Salem et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The single-cell transcriptomic landscape of early human diabetic nephropathy

(2019) Parker C. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NicheNet: modeling intercellular communication by linking ligands to target genes

(2019) Robin Browaeys et al.   NATURE METHODS

The power of one: advances in single-cell genomics in the kidney

(2019) Abbe R. Clark et al.   Nature Reviews Nephrology

CX3CL1/CX3CR1 Axis, as the Therapeutic Potential in Renal Diseases: Friend or Foe?

(2018) Quan Zhuang et al.   CURRENT GENE THERAPY

Third-generationin situhybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust

(2018) Harry M. T. Choi et al.   DEVELOPMENT

A Single-Cell Transcriptome Atlas of the Mouse Glomerulus

(2018) Nikos Karaiskos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

(2018) Matthew D. Young et al.   SCIENCE

Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Evolving Complexity of the Podocyte Cytoskeleton

(2017) Christoph Schell et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic Kidney Disease

(2017) Angela C Webster et al.   LANCET

Vascular Growth Factors and Glomerular Disease

(2016) Christina S. Bartlett et al.   Annual Review of Physiology

Human genetics of nephrotic syndrome and the quest for precision medicine

(2016) Anna Greka   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Regulating Rho GTPases and their regulators

(2016) Richard G. Hodge et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog

(2016) Maria Edeling et al.   Nature Reviews Nephrology

Exploring the genetic basis of early-onset chronic kidney disease

(2016) Asaf Vivante et al.   Nature Reviews Nephrology

A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation

(2016) Ryoichi Ishibashi et al.   Scientific Reports

Bone Morphogenetic Protein 4 and Smad1 Mediate Extracellular Matrix Production in the Development of Diabetic Nephropathy

(2015) Takeshi Matsubara et al.   DIABETES

The cell biology of renal filtration

(2015) Rizaldy P. Scott et al.   JOURNAL OF CELL BIOLOGY

The Technology and Biology of Single-Cell RNA Sequencing

(2015) Aleksandra A. Kolodziejczyk et al.   MOLECULAR CELL

Semaphorin3a Promotes Advanced Diabetic Nephropathy

(2014) Pardeep K. Aggarwal et al.   DIABETES

Rhophilin-1 Is a Key Regulator of the Podocyte Cytoskeleton and Is Essential for Glomerular Filtration

(2014) M. A. Lal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genetic causes of proteinuria and nephrotic syndrome: Impact on podocyte pathobiology

(2014) Oleh Akchurin et al.   PEDIATRIC NEPHROLOGY

The Importance of Podocyte Adhesion for a Healthy Glomerulus

(2014) Rachel Lennon et al.   Frontiers in Endocrinology

ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling

(2013) Heon Yung Gee et al.   JOURNAL OF CLINICAL INVESTIGATION

N-WASP Is Required for Stabilization of Podocyte Foot Processes

(2013) C. Schell et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The glomerular basement membrane as a barrier to albumin

(2013) Jung Hee Suh et al.   Nature Reviews Nephrology

BMP signaling and its modifiers in kidney development

(2013) Ryuichi Nishinakamura et al.   PEDIATRIC NEPHROLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

Renal involvement in mitochondrial cytopathies

(2011) Francesco Emma et al.   PEDIATRIC NEPHROLOGY

Tyrosine phosphatase beta regulates angiopoietin-Tie2 signaling in human endothelial cells

(2009) Orisha K. Yacyshyn et al.   ANGIOGENESIS

Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis

(2009) Sofie Mellberg et al.   FASEB JOURNAL

VEGF Inhibition and Renal Thrombotic Microangiopathy

(2008) Vera Eremina et al.   NEW ENGLAND JOURNAL OF MEDICINE

A New Look at Platelet-Derived Growth Factor in Renal Disease

(2007) J. Floege et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY