H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility
Authors
Keywords
GWAS, eQTL, HiChIP, CRISPRi, PrCa risk loci
Journal
AMERICAN JOURNAL OF HUMAN GENETICS
Volume 108, Issue 12, Pages 2284-2300
Publisher
Elsevier BV
Online
2021-11-24
DOI
10.1016/j.ajhg.2021.11.007
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
- (2021) David V. Conti et al. NATURE GENETICS
- Quantifying genetic effects on disease mediated by assayed gene expression levels
- (2020) Douglas W. Yao et al. NATURE GENETICS
- A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles
- (2020) Nancy Y. A. Sey et al. NATURE NEUROSCIENCE
- A simple new approach to variable selection in regression, with application to genetic fine mapping
- (2020) Gao Wang et al. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
- Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
- (2019) Fredrick R. Schumacher et al. NATURE GENETICS
- Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression
- (2019) William W. Greenwald et al. Nature Communications
- Opportunities and challenges for transcriptome-wide association studies
- (2019) Michael Wainberg et al. NATURE GENETICS
- WashU Epigenome Browser update 2019
- (2019) Daofeng Li et al. NUCLEIC ACIDS RESEARCH
- Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
- (2019) Charles P. Fulco et al. NATURE GENETICS
- A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome
- (2019) Suhn Kyong Rhie et al. Nature Communications
- Identification of significant chromatin contacts from HiChIP data by FitHiChIP
- (2019) Sourya Bhattacharyya et al. Nature Communications
- The Post-GWAS Era: From Association to Function
- (2018) Michael D. Gallagher et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A Bayesian framework for multiple trait colocalization from summary association statistics
- (2018) Claudia Giambartolomei et al. BIOINFORMATICS
- VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis
- (2018) MacIntosh Cornwell et al. BMC BIOINFORMATICS
- A Review of Prostate Cancer Genome-Wide Association Studies (GWAS)
- (2018) Sarah Benafif et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus
- (2018) Ping Gao et al. CELL
- Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19
- (2018) Junjie Tony Hua et al. CELL
- A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
- (2018) David Y. Takeda et al. CELL
- Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures
- (2018) Federico Comoglio et al. GENOME RESEARCH
- Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
- (2018) Fredrick R. Schumacher et al. NATURE GENETICS
- The long tail of oncogenic drivers in prostate cancer
- (2018) Joshua Armenia et al. NATURE GENETICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
- (2018) Tokhir Dadaev et al. Nature Communications
- Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
- (2018) Alvaro N. Barbeira et al. Nature Communications
- Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids
- (2018) Anthony M. D'Ippolito et al. Cell Systems
- Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
- (2018) Nicholas Mancuso et al. Nature Communications
- Enhancer Connectome Nominates Target Genes of Inherited Risk Variants from Inflammatory Skin Disorders
- (2018) Mark Y. Jeng et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Germline variation at 8q24 and prostate cancer risk in men of European ancestry
- (2018) Marco Matejcic et al. Nature Communications
- Prostate cancer meta-analysis from more than 145,000 men to identify 65 novel prostate cancer susceptibility loci.
- (2017) Rosalind Eeles et al. JOURNAL OF CLINICAL ONCOLOGY
- Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
- (2017) Maxwell R Mumbach et al. NATURE GENETICS
- GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
- (2017) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- A Prostate Cancer Risk Element Functions as a Repressive Loop that Regulates HOXA13
- (2017) Zhifei Luo et al. Cell Reports
- Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization
- (2017) Xiaoquan Wen et al. PLoS Genetics
- Colocalization of GWAS and eQTL Signals Detects Target Genes
- (2016) Farhad Hormozdiari et al. AMERICAN JOURNAL OF HUMAN GENETICS
- ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline
- (2016) Qian Qin et al. BMC BIOINFORMATICS
- Mapping of long-range chromatin interactions by proximity ligation-assisted ChIP-seq
- (2016) Rongxin Fang et al. CELL RESEARCH
- Re: The Molecular Taxonomy of Primary Prostate Cancer
- (2016) Thorsten Schlomm EUROPEAN UROLOGY
- Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations
- (2016) Phillippa C. Taberlay et al. GENOME RESEARCH
- Familial Risk and Heritability of Cancer Among Twins in Nordic Countries
- (2016) Lorelei A. Mucci et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
- (2016) John G Doench et al. NATURE BIOTECHNOLOGY
- Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer
- (2016) Haiyang Guo et al. NATURE GENETICS
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Integrative approaches for large-scale transcriptome-wide association studies
- (2016) Alexander Gusev et al. NATURE GENETICS
- HiChIP: efficient and sensitive analysis of protein-directed genome architecture
- (2016) Maxwell R Mumbach et al. NATURE METHODS
- Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
- (2016) Alexander Gusev et al. Nature Communications
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- (2015) Ali Amin Al Olama et al. HUMAN MOLECULAR GENETICS
- Putative Prostate Cancer Risk SNP in an Androgen Receptor-Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites
- (2015) Huajie Bu et al. HUMAN MUTATION
- Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
- (2015) Borbala Mifsud et al. NATURE GENETICS
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- A gene-based association method for mapping traits using reference transcriptome data
- (2015) Eric R Gamazon et al. NATURE GENETICS
- CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants
- (2015) Sándor Spisák et al. NATURE MEDICINE
- Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set
- (2015) S. N. Thibodeau et al. Nature Communications
- The Heritability of Prostate Cancer in the Nordic Twin Study of Cancer
- (2014) J. B. Hjelmborg et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies
- (2014) Gleb Kichaev et al. PLoS Genetics
- Topology of mammalian developmental enhancers and their regulatory landscapes
- (2013) Wouter de Laat et al. NATURE
- A high-resolution map of the three-dimensional chromatin interactome in human cells
- (2013) Fulai Jin et al. NATURE
- The Cancer Genome Atlas Pan-Cancer analysis project
- (2013) John N Weinstein et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Matrix eQTL: ultra fast eQTL analysis via large matrix operations
- (2012) A. A. Shabalin BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors
- (2012) I. K. Sur et al. SCIENCE
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- NKX3.1 Activates Cellular Response to DNA Damage
- (2010) C. Bowen et al. CANCER RESEARCH
- An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer
- (2010) N. F. Wasserman et al. GENOME RESEARCH
- Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
- (2010) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
- (2010) N. Ahmadiyeh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone H3K27ac separates active from poised enhancers and predicts developmental state
- (2010) M. P. Creyghton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Role of Androgen Receptor Mutations in Prostate Cancer Progression
- (2009) G. Brooke et al. CURRENT GENOMICS
- Multiple loci on 8q24 associated with prostate cancer susceptibility
- (2009) Ali Amin Al Olama et al. NATURE GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now