Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease

(2014) D Leongamornlert et al.   BRITISH JOURNAL OF CANCER

The Heritability of Prostate Cancer in the Nordic Twin Study of Cancer

(2014) J. B. Hjelmborg et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Association of Prostate Cancer Risk Variants with Gene Expression in Normal and Tumor Tissue

(2014) K. L. Penney et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

(2014) Qiyuan Li et al.   HUMAN MOLECULAR GENETICS

Another explanation for apparent epistasis

(2014) Andrew R. Wood et al.   NATURE

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins

(2014) Alfonso Buil et al.   NATURE GENETICS

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

(2014) Ali Amin Al Olama et al.   NATURE GENETICS

Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci

(2014) Dennis J. Hazelett et al.   PLoS Genetics

Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer

(2014) Edward J. Saunders et al.   PLoS Genetics

Genetic interactions affecting human gene expression identified by variance association mapping

(2014) Andrew Anand Brown et al.   eLife

Germline mutation in the RAD51B gene confers predisposition to breast cancer

(2013) Lisa Golmard et al.   BMC CANCER

Reduced expression of NGEP is associated with high-grade prostate cancers: a tissue microarray analysis

(2013) Monireh Mohsenzadegan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Variants at IRX4 as prostate cancer expression quantitative trait loci

(2013) Xing Xu et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

(2013) Zsofia Kote-Jarai et al.   HUMAN MOLECULAR GENETICS

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

(2013) Rosalind A Eeles et al.   NATURE GENETICS

Consortium Launches Genotyping Effort

(2013)   Cancer Discovery

Quantifying Missing Heritability at Known GWAS Loci

(2013) Alexander Gusev et al.   PLoS Genetics

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

miRcode: a map of putative microRNA target sites in the long non-coding transcriptome

(2012) Ashwini Jeggari et al.   BIOINFORMATICS

The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man

(2012) Naomi L. Sharma et al.   CANCER CELL

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

(2012) J. Wang et al.   GENOME RESEARCH

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

(2012) Nick Orr et al.   NATURE GENETICS

Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese

(2012) Shusuke Akamatsu et al.   NATURE GENETICS

Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

(2012) Jianfeng Xu et al.   NATURE GENETICS

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

Germline Mutations inHOXB13and Prostate-Cancer Risk

(2012) Charles M. Ewing et al.   NEW ENGLAND JOURNAL OF MEDICINE

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs

(2012) Simon G. Coetzee et al.   NUCLEIC ACIDS RESEARCH

The P2X7 receptor is a key modulator of aerobic glycolysis

(2012) F Amoroso et al.   Cell Death & Disease

ggbio: an R package for extending the grammar of graphics for genomic data

(2012) Tengfei Yin et al.   GENOME BIOLOGY

Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1

(2011) Changmeng Cai et al.   CANCER CELL

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

(2011) Z. Kote-Jarai et al.   HUMAN GENETICS

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer

(2011) Charles C. Chung et al.   HUMAN MOLECULAR GENETICS

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

(2011) Andrew R. Wood et al.   HUMAN MOLECULAR GENETICS

Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival

(2011) P. Y. Tan et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamic Nucleosome-Depleted Regions at Androgen Receptor Enhancers in the Absence of Ligand in Prostate Cancer Cells

(2011) C. Andreu-Vieyra et al.   MOLECULAR AND CELLULAR BIOLOGY

Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism

(2011) Taro Hitosugi et al.   MOLECULAR CELL

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

(2011) Zsofia Kote-Jarai et al.   NATURE GENETICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer

(2010) Lorna W Harries et al.   BMC CANCER

Fine scale mapping of the breast cancer 16q12 locus

(2010) Miriam S. Udler et al.   HUMAN MOLECULAR GENETICS

Tubulin tyrosine ligase like 12 links to prostate cancer through tubulin posttranslational modification and chromosome ploidy

(2010) Christine Wasylyk et al.   INTERNATIONAL JOURNAL OF CANCER

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

(2010) Ryo Takata et al.   NATURE GENETICS

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

(2009) Rosalind A Eeles et al.   NATURE GENETICS

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

(2009) Julius Gudmundsson et al.   NATURE GENETICS

Multiple loci on 8q24 associated with prostate cancer susceptibility

(2009) Ali Amin Al Olama et al.   NATURE GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Multiple Novel Prostate Cancer Predisposition Loci Confirmed by an International Study: The PRACTICAL Consortium

(2008) Z. Kote-Jarai et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Topology of NGEP, a Prostate-Specific Cell:Cell Junction Protein Widely Expressed in Many Cancers of Different Grade Level

(2008) S. Das et al.   CANCER RESEARCH

Evidence for two independent prostate cancer risk–associated loci in the HNF1B gene at 17q12

(2008) Jielin Sun et al.   NATURE GENETICS

Multiple newly identified loci associated with prostate cancer susceptibility

(2008) Rosalind A Eeles et al.   NATURE GENETICS