DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome

Association of Plasma Phospholipids with Age-Related Cognitive Impairment: Results from a Cross-Sectional Study

(2021) Ting-Ting Liu et al.   Nutrients

The Laminopathies and the Insights They Provide into the Structural and Functional Organization of the Nucleus

(2020) Xianrong Wong et al.   Annual Review of Genomics and Human Genetics

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

(2020) Florian Köhler et al.   Genome Medicine

DNA Methylation Biomarkers in Aging and Age-Related Diseases

(2020) Yasmeen Salameh et al.   Frontiers in Genetics

Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline

(2020) Ramya Potabattula et al.   AGING CELL

DNA methylation GrimAge strongly predicts lifespan and healthspan

(2019) Ake T. Lu et al.   Aging-US

Lamina Associated Domains and Gene Regulation in Development and Cancer

(2019) Silke J.A. Lochs et al.   Cells

Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy

(2019) Sirisha Marreddy Cheedipudi et al.   CIRCULATION RESEARCH

Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes

(2019) Anna Maierhofer et al.   AGING CELL

eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data

(2019) Charles E Breeze et al.   BIOINFORMATICS

Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus

(2019) Simone Granno et al.   Scientific Reports

The role of lipid metabolism in aging, lifespan regulation, and age‐related disease

(2019) Adiv A. Johnson et al.   AGING CELL

Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells

(2019) Angels Almenar-Queralt et al.   NATURE GENETICS

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation

(2019) Larissa Haertle et al.   Clinical Epigenetics

An epigenetic biomarker of aging for lifespan and healthspan

(2018) Morgan E. Levine et al.   Aging-US

DNA methylation loss in late-replicating domains is linked to mitotic cell division

(2018) Wanding Zhou et al.   NATURE GENETICS

Nuclear Lamins: Thin Filaments with Major Functions

(2018) Rebecca de Leeuw et al.   TRENDS IN CELL BIOLOGY

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

(2018) Steve Horvath et al.   Aging-US

Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors

(2018) Ramya Potabattula et al.   Epigenomics

methylGSA: a Bioconductor package and Shiny app for DNA methylation data length bias adjustment in gene set testing

(2018) Xu Ren et al.   BIOINFORMATICS

Epigenetic dysregulation of protocadherins in human disease

(2017) Nady El Hajj et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Somatic overgrowth disorders of the PI3K/AKT/mTOR pathway & therapeutic strategies

(2016) Kim M. Keppler-Noreuil et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Epigenetic dysregulation in the developing Down syndrome cortex

(2016) Nady El Hajj et al.   Epigenetics

Molecular insights into the premature aging disease progeria

(2016) Sandra Vidak et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Neighboring Gene Regulation by Antisense Long Non-Coding RNAs

(2015) Victoria Villegas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DNA methylation age of blood predicts all-cause mortality in later life

(2015) Riccardo E Marioni et al.   GENOME BIOLOGY

Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin

(2015) Eivind G Lund et al.   Nucleus

Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin

(2015) Eivind G Lund et al.   Nucleus

Reference-free cell mixture adjustments in analysis of DNA methylation data

(2014) Eugene Andres Houseman et al.   BIOINFORMATICS

Enriched domain detector: a program for detection of wide genomic enrichment domains robust against local variations

(2014) Eivind Lund et al.   NUCLEIC ACIDS RESEARCH

Investigating the purpose of prelamin A processing

(2014) Brandon S. J. Davies et al.   Nucleus

Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization

(2013) K. D. Hansen et al.   GENOME RESEARCH

Phospholipids and Alzheimer’s Disease: Alterations, Mechanisms and Potential Biomarkers

(2013) Marko Kosicek et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gene regulation by antisense transcription

(2013) Vicent Pelechano et al.   NATURE REVIEWS GENETICS

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

(2012) Holger Heyn et al.   Epigenetics

Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome

(2012) R. P. McCord et al.   GENOME RESEARCH

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

(2012) W. Meuleman et al.   GENOME RESEARCH

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Nuclear lamins and laminopathies

(2011) Howard J. Worman   JOURNAL OF PATHOLOGY

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

(2011) Benjamin P Berman et al.   NATURE GENETICS

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria

(2010) Lidia Hernandez et al.   DEVELOPMENTAL CELL

Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

(2010) M. D. W. Piper et al.   JOURNAL OF INTERNAL MEDICINE

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

(2010) Daan Peric-Hupkes et al.   MOLECULAR CELL

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Regulatory roles of natural antisense transcripts

(2009) Mohammad Ali Faghihi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

(2009) Veeranna et al.   NEUROBIOLOGY OF AGING

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Sarcoplasmic Reticulum Ca2+ Release Declines in Muscle Fibers from Aging Mice

(2008) Ramón Jiménez-Moreno et al.   BIOPHYSICAL JOURNAL

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

Deregulation of sphingolipid metabolism in Alzheimer's disease

(2008) Xingxuan He et al.   NEUROBIOLOGY OF AGING