Phospholipids and Alzheimer’s Disease: Alterations, Mechanisms and Potential Biomarkers

Low Cerebrospinal Fluid Sulfatide Predicts Progression of White Matter Lesions – The LADIS Study

(2012) Michael Jonsson et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

The Roles of Neutral Sphingomyelinases in Neurological Pathologies

(2012) Charles R. Horres et al.   NEUROCHEMICAL RESEARCH

Elevated cerebrospinal fluid sphingomyelin levels in prodromal Alzheimer's disease

(2012) M. Kosicek et al.   NEUROSCIENCE LETTERS

Sphingolipids: Critical players in Alzheimer’s disease

(2012) Gerhild van Echten-Deckert et al.   PROGRESS IN LIPID RESEARCH

Distribution of lipids in human brain

(2011) Antonio Veloso et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease

(2011) C Dirk Keene et al.   CURRENT OPINION IN NEUROBIOLOGY

Apolipoprotein E in Alzheimer's disease and other neurological disorders

(2011) Philip B Verghese et al.   LANCET NEUROLOGY

Lipid changes in the aged brain: Effect on synaptic function and neuronal survival

(2011) María Dolores Ledesma et al.   PROGRESS IN LIPID RESEARCH

Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss

(2010) Michelle M. Mielke et al.   Alzheimers & Dementia

Nano-HPLC–MS analysis of phospholipids in cerebrospinal fluid of Alzheimer’s disease patients—a pilot study

(2010) M. Kosicek et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

(2010) Marko Kosicek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis

(2010) Norman J. Haughey et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease

(2010) Xianlin Han   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Alterations of the Sphingolipid Pathway in Alzheimer’s Disease: New Biomarkers and Treatment Targets?

(2010) Michelle M. Mielke et al.   NEUROMOLECULAR MEDICINE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cholesterol in Alzheimers Disease: Unresolved Questions

(2009) Massimo Stefani et al.   Current Alzheimer Research

CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment

(2009) Niklas Mattsson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Cholesterol metabolism and transport in the pathogenesis of Alzheimer’s disease

(2009) Ian J. Martins et al.   JOURNAL OF NEUROCHEMISTRY

S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1

(2008) Haipeng Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer Disease Aβ Production in the Absence ofS-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts

(2008) Kulandaivelu S. Vetrivel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioactive sphingolipids: metabolism and function

(2008) Nana Bartke et al.   JOURNAL OF LIPID RESEARCH

The challenge of lipid rafts

(2008) Linda J. Pike   JOURNAL OF LIPID RESEARCH

Deregulation of sphingolipid metabolism in Alzheimer's disease

(2008) Xingxuan He et al.   NEUROBIOLOGY OF AGING

Serum sphingomyelins and ceramides are early predictors of memory impairment

(2008) Michelle M. Mielke et al.   NEUROBIOLOGY OF AGING

Efficient Inhibition of the Alzheimer's Disease  -Secretase by Membrane Targeting

(2008) L. Rajendran et al.   SCIENCE

ApoE4 disrupts sterol and sphingolipid metabolism in Alzheimer's but not normal brain

(2007) Veera Venkata Ratnam Bandaru et al.   NEUROBIOLOGY OF AGING