Integrative proteome analysis implicates aberrant RNA splicing in impaired developmental potential of aged mouse oocytes

Dynamic Alternative Splicing During Mouse Preimplantation Embryo Development

(2020) Yongqiang Xing et al.   Frontiers in Bioengineering and Biotechnology

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion

(2020) Isabel Gómez-Redondo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Compromised global embryonic transcriptome associated with advanced maternal age

(2019) Blair R. McCallie et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

RNA‐Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation

(2019) Hong‐Bin Liu et al.   Advanced Science

Loss of HDAC3 contributes to meiotic defects in aged oocytes

(2019) Yongfu He et al.   AGING CELL

SETD2 reduction adversely affects the development of mouse early embryos

(2019) Chunling Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chromosome errors in human eggs shape natural fertility over reproductive life span

(2019) Jennifer R. Gruhn et al.   SCIENCE

SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

(2018) Juan Zeng et al.   AGING CELL

Regulatory RNA binding proteins contribute to the transcriptome-wide splicing alterations in human cellular senescence

(2018) Qiongye Dong et al.   Aging-US

Fertility and infertility: Definition and epidemiology

(2018) Mélodie Vander Borght et al.   CLINICAL BIOCHEMISTRY

Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events

(2018) Marco Conti et al.   HUMAN REPRODUCTION UPDATE

PUF60-activated exons uncover altered 3′ splice-site selection by germline missense mutations in a single RRM

(2018) Jana Královičová et al.   NUCLEIC ACIDS RESEARCH

Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice

(2018) Jing Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Unique Mechanisms of Cellular Proliferation, Migration and Apoptosis are Regulated through Oocyte Maturational Development—A Complete Transcriptomic and Histochemical Study

(2018) Błażej Chermuła et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging

(2017) Antonio Capalbo et al.   HUMAN REPRODUCTION UPDATE

Long-term melatonin treatment delays ovarian aging

(2017) Hiroshi Tamura et al.   JOURNAL OF PINEAL RESEARCH

The Reactome Pathway Knowledgebase

(2017) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa

(2017) Julio M. Castaneda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advanced maternal age causes adverse programming of mouse blastocysts leading to altered growth and impaired cardiometabolic health in post-natal life

(2016) M.A. Velazquez et al.   HUMAN REPRODUCTION

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Regulation of Alternative Splicing Through Coupling with Transcription and Chromatin Structure

(2015) Shiran Naftelberg et al.   Annual Review of Biochemistry

The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing

(2015) K.-i. Abe et al.   EMBO JOURNAL

Reproduction at an advanced maternal age and maternal health

(2015) Mark V. Sauer   FERTILITY AND STERILITY

Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes

(2015) T. Trapphoff et al.   HUMAN REPRODUCTION

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Age-related Infertility

(2015) Natalie M. Crawford et al.   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age

(2015) Petros Marangos et al.   Nature Communications

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Context-dependent control of alternative splicing by RNA-binding proteins

(2014) Xiang-Dong Fu et al.   NATURE REVIEWS GENETICS

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data

(2014) Shihao Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome analysis of early lineage specification in bovine embryos

(2014) Myriam Demant et al.   PROTEOMICS

Maternal age effect on mouse oocytes: new biological insight from proteomic analysis

(2014) Caroline Schwarzer et al.   REPRODUCTION

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

The menopause and aging, a comparative perspective

(2013) Caleb E. Finch   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The maternal to zygotic transition in mammals

(2013) Lei Li et al.   MOLECULAR ASPECTS OF MEDICINE

Lifestyle factors and reproductive health: taking control of your fertility

(2013) Rakesh Sharma et al.   Reproductive Biology and Endocrinology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Spliceosome Database: a tool for tracking components of the spliceosome

(2012) Ivan Cvitkovic et al.   NUCLEIC ACIDS RESEARCH

Inferring direct DNA binding from ChIP-seq

(2012) Timothy L. Bailey et al.   NUCLEIC ACIDS RESEARCH

SpliceAid-F: a database of human splicing factors and their RNA-binding sites

(2012) Matteo Giulietti et al.   NUCLEIC ACIDS RESEARCH

Identification of four genes required for mammalian blastocyst formation

(2012) Marc Maserati et al.   ZYGOTE

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

(2011) Lorna W. Harries et al.   AGING CELL

Maternal control of early mouse development

(2010) L. Li et al.   DEVELOPMENT

Developmental consequences of alternative Bcl-x splicing during preimplantation embryo development

(2010) Alagammal Perumalsamy et al.   FEBS Journal

Ovarian follicle loss in humans and mice: lessons from statistical model comparison

(2010) J. E. Coxworth et al.   HUMAN REPRODUCTION

RBPDB: a database of RNA-binding specificities

(2010) K. B. Cook et al.   NUCLEIC ACIDS RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development

(2008) Maria Paola Paronetto et al.   GENE EXPRESSION PATTERNS

Oocyte senescence: A firm link to age-related female subfertility

(2008) Carla Tatone   GYNECOLOGICAL ENDOCRINOLOGY

Human female meiosis: what makes a good egg go bad?

(2008) Patricia A. Hunt et al.   TRENDS IN GENETICS