Non-spherical micro- and nanoparticles for drug delivery: Progress over 15 years
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Non-spherical micro- and nanoparticles for drug delivery: Progress over 15 years
Authors
Keywords
Particle, Shape, Drug delivery, Geometry, Non-spherical, Anisotropic, Internalization, Targeting, Immune response
Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 177, Issue -, Pages 113807
Publisher
Elsevier BV
Online
2021-05-22
DOI
10.1016/j.addr.2021.05.017
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cellular fate of deformable needle-shaped PLGA-PEG fibers
- (2020) Bokai Zhang et al. Acta Biomaterialia
- Targeting Strategies for Tissue-Specific Drug Delivery
- (2020) Zongmin Zhao et al. CELL
- Synthetic high-density lipoprotein nanodiscs for personalized immunotherapy against gliomas
- (2020) Lindsay Scheetz et al. CLINICAL CANCER RESEARCH
- Cellular backpacks for macrophage immunotherapy
- (2020) C. Wyatt Shields et al. Science Advances
- Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal
- (2020) Elana Ben-Akiva et al. Science Advances
- Drug-Directed Morphology Changes in Polymerization-Induced Self-Assembly (PISA) Influence the Biological Behavior of Nanoparticles
- (2020) Cheng Cao et al. ACS Applied Materials & Interfaces
- Injectable, ribbon-like microconfetti biopolymer platform for vaccine applications
- (2020) Kathryn Moore et al. ACS Applied Materials & Interfaces
- Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy
- (2020) Xueguang Lu et al. Science Translational Medicine
- Neutrophils preferentially phagocytose elongated particles—An opportunity for selective targeting in acute inflammatory diseases
- (2020) Hanieh Safari et al. Science Advances
- Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs
- (2020) Alireza Hassani Najafabadi et al. NANO LETTERS
- Fabrication and Characterization of Non-spherical Polymeric Particles
- (2020) Ajinkya Patil et al. Journal of Pharmaceutical Innovation
- Engineering precision nanoparticles for drug delivery
- (2020) Michael J. Mitchell et al. NATURE REVIEWS DRUG DISCOVERY
- Nanoparticle Surface Functionalization: How to Improve Biocompatibility and Cellular Internalization
- (2020) Gennaro Sanità et al. Frontiers in Molecular Biosciences
- Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers
- (2019) Zongmin Zhao et al. ADVANCED DRUG DELIVERY REVIEWS
- Modulated Protein Delivery to Engineer Tissue Repair
- (2019) Molly S. Shoichet et al. TISSUE ENGINEERING PART A
- Shape of ligand immobilized particles dominates and amplifies the macrophage cytokine response to ligands
- (2019) Anusha Garapaty et al. PLoS One
- Modular fabrication of intelligent material-tissue interfaces for bioinspired and biomimetic devices
- (2019) John R. Clegg et al. PROGRESS IN MATERIALS SCIENCE
- Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions
- (2019) A. Da Silva-Candal et al. JOURNAL OF CONTROLLED RELEASE
- Novel fibronectin-targeted nanodisk drug delivery system displayed superior efficacy against prostate cancer compared with nanospheres
- (2019) Luyao Wang et al. Nano Research
- Molecular Programming of Biodegradable Nanoworms via Ionically Induced Morphology Switch toward Asymmetric Therapeutic Carriers
- (2019) Shoupeng Cao et al. Small
- Nonspherical Nanoparticle Shape Stability Is Affected by Complex Manufacturing Aspects: Its Implications for Drug Delivery and Targeting
- (2019) Bernard Manuel Haryadi et al. Advanced Healthcare Materials
- Light to Shape the Future: From Photolithography to 4D Printing
- (2019) Jesús del Barrio et al. Advanced Optical Materials
- Resolution enhancement in scanning electron microscopy using deep learning
- (2019) Kevin de Haan et al. Scientific Reports
- Biomaterial-mediated reprogramming of monocytes via microparticle phagocytosis for sustained modulation of macrophage phenotype
- (2019) Kathryn L. Wofford et al. Acta Biomaterialia
- Drug delivery to macrophages: A review of targeting drugs and drug carriers to macrophages for inflammatory diseases
- (2019) Wei He et al. ADVANCED DRUG DELIVERY REVIEWS
- Role of particle shape on efficient and organ-based drug delivery
- (2019) Sara Nejati et al. EUROPEAN POLYMER JOURNAL
- One-step fabrication of low cytotoxic anisotropic poly(2-hydroxyethyl methacrylate-co-methacrylic acid) particles for efficient release of DOX
- (2019) Zahra Vatankhah et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation
- (2018) Randall A. Meyer et al. Acta Biomaterialia
- Injectable nanocomposite cryogels for versatile protein drug delivery
- (2018) Sandeep T. Koshy et al. Acta Biomaterialia
- Practical guidelines for the characterization and quality control of pure drug nanoparticles and nano-cocrystals in the pharmaceutical industry
- (2018) Leena Peltonen ADVANCED DRUG DELIVERY REVIEWS
- Detection of nanoplastics in food by asymmetric flow field-flow fractionation coupled to multi-angle light scattering: possibilities, challenges and analytical limitations
- (2018) Manuel Correia et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Application of asymmetric flow field-flow fractionation (AF4) and multiangle light scattering (MALS) for the evaluation of changes in the product molar mass during PVP-b-PAMPS synthesis
- (2018) Catalina Fuentes et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
- (2018) Haiying Zhang et al. NATURE CELL BIOLOGY
- Shape-dependent adjuvanticity of nanoparticle-conjugated RNA adjuvants for intranasal inactivated influenza vaccines
- (2018) Taiyu Tazaki et al. RSC Advances
- Application of Light Scattering Techniques to Nanoparticle Characterization and Development
- (2018) Patrícia M. Carvalho et al. Frontiers in Chemistry
- PEGylation of model drug carriers enhances phagocytosis by primary human neutrophils
- (2018) William J. Kelley et al. Acta Biomaterialia
- Influence of particle size and shape on their margination and wall-adhesion: implications in drug delivery vehicle design across nano-to-micro scale
- (2018) Michaela Cooley et al. Nanoscale
- Self-Assembly of Immune Signals Improves Codelivery to Antigen Presenting Cells and Accelerates Signal Internalization, Processing Kinetics, and Immune Activation
- (2018) Michelle L. Bookstaver et al. Small
- Development of PLGA micro- and nanorods with high capacity of surface ligand conjugation for enhanced targeted delivery
- (2018) Jiafu Cao et al. Asian Journal of Pharmaceutical Sciences
- Membrane Wrapping Efficiency of Elastic Nanoparticles during Endocytosis: Size and Shape Matter
- (2018) Zhiqiang Shen et al. ACS Nano
- Shape-based separation of synthetic microparticles
- (2018) Peter L. Mage et al. NATURE MATERIALS
- Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents
- (2018) Arianna Castoldi et al. PHARMACEUTICAL RESEARCH
- Characterisation of particles in solution – a perspective on light scattering and comparative technologies
- (2018) Ciarán Manus Maguire et al. SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
- Unique size and shape-dependent uptake behaviors of non-spherical nanoparticles by endothelial cells due to a shearing flow
- (2017) Patrick Jurney et al. JOURNAL OF CONTROLLED RELEASE
- Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
- (2017) Peter Popp Wibroe et al. Nature Nanotechnology
- How cells engulf: a review of theoretical approaches to phagocytosis
- (2017) David M Richards et al. REPORTS ON PROGRESS IN PHYSICS
- A general strategy to synthesize chemically and topologically anisotropic Janus particles
- (2017) Jun-Bing Fan et al. Science Advances
- Loading Capacity versus Enzyme Activity in Anisotropic and Spherical Calcium Carbonate Microparticles
- (2016) Senem Donatan et al. ACS Applied Materials & Interfaces
- A quick guide to light microscopy in cell biology
- (2016) Kurt Thorn MOLECULAR BIOLOGY OF THE CELL
- Designer vaccine nanodiscs for personalized cancer immunotherapy
- (2016) Rui Kuai et al. NATURE MATERIALS
- Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release
- (2016) Elizabeth Hinde et al. Nature Nanotechnology
- Saquinavir Loaded Acetalated Dextran Microconfetti – a Long Acting Protease Inhibitor Injectable
- (2016) Michael A. Collier et al. PHARMACEUTICAL RESEARCH
- Decorating Nanoparticle Surface for Targeted Drug Delivery: Opportunities and Challenges
- (2016) Zhiqiang Shen et al. Polymers
- Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds
- (2015) Kara L. Spiller et al. BIOMATERIALS
- Controlled One-on-One Encounters between Immune Cells and Microbes Reveal Mechanisms of Phagocytosis
- (2015) Volkmar Heinrich BIOPHYSICAL JOURNAL
- An automated multidimensional thin film stretching device for the generation of anisotropic polymeric micro- and nanoparticles
- (2015) Randall A. Meyer et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation
- (2015) Aaron C. Anselmo et al. JOURNAL OF CONTROLLED RELEASE
- Shape and size-dependent immune response to antigen-carrying nanoparticles
- (2015) Sunny Kumar et al. JOURNAL OF CONTROLLED RELEASE
- Preparation of non-spherical particles from amphiphilic block copolymers
- (2015) Kristian Kempe et al. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
- Principles of nanoparticle design for overcoming biological barriers to drug delivery
- (2015) Elvin Blanco et al. NATURE BIOTECHNOLOGY
- Distribution and Cellular Uptake of PEGylated Polymeric Particles in the Lung Towards Cell-Specific Targeted Delivery
- (2015) Tammy W. Shen et al. PHARMACEUTICAL RESEARCH
- Liposome-Loaded Cell Backpacks
- (2015) Roberta Polak et al. Advanced Healthcare Materials
- The influence of the size and aspect ratio of anisotropic, porous CaCO3 particles on their uptake by cells
- (2015) Bogdan Parakhonskiy et al. JOURNAL OF NANOBIOTECHNOLOGY
- High-Relaxivity Superparamagnetic Iron Oxide Nanoworms with Decreased Immune Recognition and Long-Circulating Properties
- (2014) Guankui Wang et al. ACS Nano
- Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries
- (2014) Aaron C. Anselmo et al. ACS Nano
- In vivo evaluation of vascular-targeted spheroidal microparticles for imaging and drug delivery application in atherosclerosis
- (2014) Katawut Namdee et al. ATHEROSCLEROSIS
- The importance of nanoparticle shape in cancer drug delivery
- (2014) Nghia P Truong et al. Expert Opinion on Drug Delivery
- Influence of particle geometry and PEGylation on phagocytosis of particulate carriers
- (2014) Roman Mathaes et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Thermally activated reversible shape switch of polymer particles
- (2014) Tao Gong et al. Journal of Materials Chemistry B
- A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes
- (2013) Jared F. Stefanick et al. ACS Nano
- Nanoparticle Geometry and Surface Orientation Influence Mode of Cellular Uptake
- (2013) Heather Herd et al. ACS Nano
- Orientation-Specific Attachment of Polymeric Microtubes on Cell Surfaces
- (2013) Jonathan B. Gilbert et al. ADVANCED MATERIALS
- Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery
- (2013) Zhuxian Zhou et al. BIOMATERIALS
- Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells
- (2013) Joel C. Sunshine et al. BIOMATERIALS
- Application of different analytical methods for the characterization of non-spherical micro- and nanoparticles
- (2013) Roman Mathaes et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Role of Nanoparticle Geometry in Endocytosis: Laying Down to Stand Up
- (2013) Changjin Huang et al. NANO LETTERS
- Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles
- (2013) Randall Toy et al. Nanomedicine
- Mammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanisms
- (2013) R. Agarwal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Particle shape enhances specificity of antibody-displaying nanoparticles
- (2013) Sutapa Barua et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced Delivery of Chemotherapy to Tumors Using a Multicomponent Nanochain with Radio-Frequency-Tunable Drug Release
- (2012) Pubudu M. Peiris et al. ACS Nano
- Discoidal Porous Silicon Particles: Fabrication and Biodistribution in Breast Cancer Bearing Mice
- (2012) Biana Godin et al. ADVANCED FUNCTIONAL MATERIALS
- Engineering Nano- and Microparticles to Tune Immunity
- (2012) James J. Moon et al. ADVANCED MATERIALS
- The preferential targeting of the diseased microvasculature by disk-like particles
- (2012) Giulia Adriani et al. BIOMATERIALS
- Formulation and evaluation of Nimodipine-loaded solid lipid nanoparticles delivered via lymphatic transport system
- (2012) Shailesh S. Chalikwar et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Production and Characterization of Anisotropic Particles from Biodegradable Materials
- (2012) Francis S. Romanski et al. LANGMUIR
- The influence of size, shape and vessel geometry on nanoparticle distribution
- (2012) Jifu Tan et al. Microfluidics and Nanofluidics
- The shape effect of PEGylated mesoporous silica nanoparticles on cellular uptake pathway in Hela cells
- (2012) Nanjing Hao et al. MICROPOROUS AND MESOPOROUS MATERIALS
- PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics
- (2012) Jillian L. Perry et al. NANO LETTERS
- Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking
- (2012) Xiaopin Duan et al. Small
- PRINT: A Novel Platform Toward Shape and Size Specific Nanoparticle Theranostics
- (2011) Jillian L. Perry et al. ACCOUNTS OF CHEMICAL RESEARCH
- Aspect Ratio Determines the Quantity of Mesoporous Silica Nanoparticle Uptake by a Small GTPase-Dependent Macropinocytosis Mechanism
- (2011) Huan Meng et al. ACS Nano
- The Shape Effect of Mesoporous Silica Nanoparticles on Biodistribution, Clearance, and Biocompatibility in Vivo
- (2011) Xinglu Huang et al. ACS Nano
- Cell-Based Drug Delivery Devices Using Phagocytosis-Resistant Backpacks
- (2011) Nishit Doshi et al. ADVANCED MATERIALS
- Fluorescent Nanorods and Nanospheres for Real-Time In Vivo Probing of Nanoparticle Shape-Dependent Tumor Penetration
- (2011) Vikash P. Chauhan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems
- (2011) Judith Kuntsche et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution
- (2011) Anne L. van de Ven et al. JOURNAL OF CONTROLLED RELEASE
- Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge—an ex vivo and in silico approach
- (2011) Julian Kirch et al. JOURNAL OF CONTROLLED RELEASE
- Microfluidic synthesis and post processing of non-spherical polymeric microparticles
- (2011) David Baah et al. Microfluidics and Nanofluidics
- Potent Engineered PLGA Nanoparticles by Virtue of Exceptionally High Chemotherapeutic Loadings
- (2011) Elizabeth M. Enlow et al. NANO LETTERS
- More Effective Nanomedicines through Particle Design
- (2011) Jin Wang et al. Small
- Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages
- (2010) Arnida et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Polymer particle shape independently influences binding and internalization by macrophages
- (2010) Gaurav Sharma et al. JOURNAL OF CONTROLLED RELEASE
- Particle Shape: A New Design Parameter for Passive Targeting In Splenotropic Drug Delivery
- (2010) Padma V. Devarajan et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Needle-shaped polymeric particles induce transient disruption of cell membranes
- (2010) N. Doshi et al. Journal of the Royal Society Interface
- Analysis of the Migration of Rigid Polymers and Nanorods in a Rotating Viscometric Flow
- (2010) Joontaek Park et al. MACROMOLECULES
- Polymer particles that switch shape in response to a stimulus
- (2010) J.-W. Yoo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles
- (2009) Hong Jin et al. ACS Nano
- Super-Resolution Fluorescence Microscopy
- (2009) Bo Huang et al. Annual Review of Biochemistry
- The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function
- (2009) Xinglu Huang et al. BIOMATERIALS
- Size and shape effects in the biodistribution of intravascularly injected particles
- (2009) P. Decuzzi et al. JOURNAL OF CONTROLLED RELEASE
- Scalable, Shape-Specific, Top-Down Fabrication Methods for the Synthesis of Engineered Colloidal Particles
- (2009) Timothy J. Merkel et al. LANGMUIR
- Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry
- (2009) Jin-Wook Yoo et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Droplet Microfluidics for Fabrication of Non-Spherical Particles
- (2009) Ho Cheung Shum et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Flexible Filaments forin VivoImaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage
- (2009) David A. Christian et al. MOLECULAR PHARMACEUTICS
- Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows
- (2009) Sei-Young Lee et al. NANOTECHNOLOGY
- Systematic Surface Engineering of Magnetic Nanoworms for In vivo Tumor Targeting
- (2009) Ji-Ho Park et al. Small
- The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows
- (2008) F. Gentile et al. JOURNAL OF BIOMECHANICS
- Microfluidic-based synthesis of non-spherical magnetic hydrogel microparticles
- (2008) Dae Kun Hwang et al. LAB ON A CHIP
- Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions
- (2008) Cuiping Pan et al. MOLECULAR & CELLULAR PROTEOMICS
- Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers
- (2008) Silvia Muro et al. MOLECULAR THERAPY
- Surface Functionalization of Living Cells with Multilayer Patches
- (2008) Albert J. Swiston et al. NANO LETTERS
- Templated Open Flocs of Nanorods for Enhanced Pulmonary Delivery with Pressurized Metered Dose Inhalers
- (2008) Josh D. Engstrom et al. PHARMACEUTICAL RESEARCH
- Shape Induced Inhibition of Phagocytosis of Polymer Particles
- (2008) Julie A. Champion et al. PHARMACEUTICAL RESEARCH
- Intravascular Delivery of Particulate Systems: Does Geometry Really Matter?
- (2008) Paolo Decuzzi et al. PHARMACEUTICAL RESEARCH
- Role of Particle Size in Phagocytosis of Polymeric Microspheres
- (2008) Julie A. Champion et al. PHARMACEUTICAL RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now