Core-shell lipoplexes inducing active macropinocytosis promote intranasal delivery of c-Myc siRNA for treatment of glioblastoma

Macropinocytosis confers resistance to therapies targeting cancer anabolism

(2020) Vaishali Jayashankar et al.   Nature Communications

Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats

(2020) Tomoyuki Furubayashi et al.   Pharmaceutics

Targeted crystallization of mixed-charge nanoparticles in lysosomes induces selective death of cancer cells

(2020) Magdalena Borkowska et al.   Nature Nanotechnology

Nose-to-brain drug delivery system with ligand/cell-penetrating peptide-modified polymeric nano-micelles for intracerebral gliomas

(2020) Takanori Kanazawa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Macropinocytosis in Different Cell Types: Similarities and Differences

(2020) Xiao Peng Lin et al.   Membranes

Macropinocytosis as a cell entry route for peptide-functionalized and bystander nanoparticles

(2020) Yue-Xuan Li et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced nose-to-brain delivery of tranilast using liquid crystal formulations

(2020) Gerard Lee See et al.   JOURNAL OF CONTROLLED RELEASE

Small interfering RNA for cancer treatment: overcoming hurdles in delivery

(2020) Nitin Bharat Charbe et al.   Acta Pharmaceutica Sinica B

Myeloid Cells in Glioblastoma Microenvironment

(2020) Alessandra De Leo et al.   Cells

Biodegradable Hyaluronic Acid Modified with Tetraglycine-l-octaarginine as a Safe Adjuvant for Mucosal Vaccination

(2019) Masami Ukawa et al.   MOLECULAR PHARMACEUTICS

Ligand-Modified Cell Membrane Enables the Targeted Delivery of Drug Nanocrystals to Glioma

(2019) Zhilan Chai et al.   ACS Nano

Genetic and molecular epidemiology of adult diffuse glioma

(2019) Annette M. Molinaro et al.   Nature Reviews Neurology

Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

(2019) Byungji Kim et al.   ADVANCED MATERIALS

Octopus-like Flexible Vector for Noninvasive Intraocular Delivery of Short Interfering Nucleic Acids

(2019) Kuan Jiang et al.   NANO LETTERS

Baicalein enhances the antitumor efficacy of docetaxel on nonsmall cell lung cancer in a β‐catenin‐dependent manner

(2019) Linwei Lu et al.   PHYTOTHERAPY RESEARCH

Therapeutic Effects in a Transient Middle Cerebral Artery Occlusion Rat Model by Nose-To-Brain Delivery of Anti-TNF-Alpha siRNA with Cell-Penetrating Peptide-Modified Polymer Micelles

(2019) Takanori Kanazawa et al.   Pharmaceutics

Nose-to-brain delivery of enveloped RNA - cell permeating peptide nanocomplexes for the treatment of neurodegenerative diseases

(2019) Eleni Samaridou et al.   BIOMATERIALS

Myristic Acid-Modified DA7R Peptide for Whole-Process Glioma-Targeted Drug Delivery

(2018) Man Ying et al.   ACS Applied Materials & Interfaces

PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells

(2018) Seong M. Kim et al.   Cancer Discovery

Surface-Modified Nanocarriers for Nose-to-Brain Delivery: From Bioadhesion to Targeting

(2018) Fabio Sonvico et al.   Pharmaceutics

Coumarin-Based Fluorescent Probes for Super-resolution and Dynamic Tracking of Lipid Droplets

(2018) Hongkang Xu et al.   ANALYTICAL CHEMISTRY

Delivery strategies and potential targets for siRNA in major cancer types

(2016) So Jin Lee et al.   ADVANCED DRUG DELIVERY REVIEWS

Use of a non-covalent cell-penetrating peptide strategy to enhance the nasal delivery of interferon beta and its PEGylated form

(2016) Yuko Iwase et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanoparticle transport across in vitro olfactory cell monolayers

(2016) Oihane Gartziandia et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cell-Penetrating Peptide Penetratin as a Potential Tool for Developing Effective Nasal Vaccination Systems

(2016) Keiya Muto et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Puerarin transport across a Calu-3 cell monolayer – an in vitro model of nasal mucosa permeability and the influence of paeoniflorin and menthol

(2016) Lin Zhang et al.   Drug Design Development and Therapy

Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

(2016) Tingting Lin et al.   Acta Pharmaceutica Sinica B

Whole inactivated avian Influenza H9N2 viruses induce nasal submucosal dendritic cells to sample luminal viruses via transepithelial dendrites and trigger subsequent DC maturation

(2015) Tao Qin et al.   VACCINE

Delivery of siRNA to the brain using a combination of nose-to-brain delivery and cell-penetrating peptide-modified nano-micelles

(2013) T. Kanazawa et al.   BIOMATERIALS

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

Cell entry of cell penetrating peptides: tales of tails wagging dogs

(2012) Arwyn T. Jones et al.   JOURNAL OF CONTROLLED RELEASE

Cell-Penetrating Peptide-Linked Polymers as Carriers for Mucosal Vaccine Delivery

(2012) Shinji Sakuma et al.   MOLECULAR PHARMACEUTICS

Cell-Penetrating Peptide-Modified Block Copolymer Micelles Promote Direct Brain Delivery via Intranasal Administration

(2011) Takanori Kanazawa et al.   PHARMACEUTICAL RESEARCH

Effect of Nanoparticle Surface Charge at the Plasma Membrane and Beyond

(2010) Rochelle R. Arvizo et al.   NANO LETTERS