Therapeutic Effects in a Transient Middle Cerebral Artery Occlusion Rat Model by Nose-To-Brain Delivery of Anti-TNF-Alpha siRNA with Cell-Penetrating Peptide-Modified Polymer Micelles

Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke

(2019) Po-Wah So et al.   International Journal of Nanomedicine

Current Treatment Options in Neurology—SMA Therapeutics

(2019) Megan A. Waldrop et al.   Current Treatment Options in Neurology

Development of Noninvasive Drug Delivery Systems to the Brain for the Treatment of Brain/Central Nervous System Diseases

(2018) Takanori Kanazawa   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery

(2018) Niyanta N. Kumar et al.   JOURNAL OF CONTROLLED RELEASE

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery

(2018) Takanori Kanazawa et al.   Jove-Journal of Visualized Experiments

Enhancement of nose-to-brain delivery of hydrophilic macromolecules with stearate- or polyethylene glycol-modified arginine-rich peptide

(2017) Takanori Kanazawa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of an Enhanced Nose-to-Brain Delivery of Insulin on Mild and Progressive Memory Loss in the Senescence-Accelerated Mouse

(2017) Noriyasu Kamei et al.   MOLECULAR PHARMACEUTICS

Prolongation of Life in Rats with Malignant Glioma by Intranasal siRNA/Drug Codelivery to the Brain with Cell-Penetrating Peptide-Modified Micelles

(2014) Takanori Kanazawa et al.   MOLECULAR PHARMACEUTICS

Strategies To Deliver Peptide Drugs to the Brain

(2014) Aikaterini Lalatsa et al.   MOLECULAR PHARMACEUTICS

Delivery of siRNA to the brain using a combination of nose-to-brain delivery and cell-penetrating peptide-modified nano-micelles

(2013) T. Kanazawa et al.   BIOMATERIALS

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Cell-Penetrating Peptide-Modified Block Copolymer Micelles Promote Direct Brain Delivery via Intranasal Administration

(2011) Takanori Kanazawa et al.   PHARMACEUTICAL RESEARCH

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

(2011) Jiyong Zhang et al.   STROKE

Development of cell-penetrating peptide-modified MPEG-PCL diblock copolymeric nanoparticles for systemic gene delivery

(2010) Ko Tanaka et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vivoover-expression of interleukin-10 increases resistance to focal brain ischemia in mice

(2009) Fabienne de Bilbao et al.   JOURNAL OF NEUROCHEMISTRY

4.5 Hours

(2009) Stephen M. Davis et al.   STROKE

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

(2008) Leah R Hanson et al.   BMC NEUROSCIENCE

Toll-like receptor signaling in endogenous neuroprotection and stroke

(2008) B.J. Marsh et al.   NEUROSCIENCE