Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats

Validation of Human MDR1-MDCK and BCRP-MDCK Cell Lines to Improve the Prediction of Brain Penetration

(2019) Bo Feng et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmacological characterization of the 3D MucilAir™ nasal model

(2019) Clément Mercier et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Organic cation transporter function in different in vitro models of human lung epithelium

(2015) Johanna J. Salomon et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Drug Transporter Protein Quantification of Immortalized Human Lung Cell Lines Derived from Tracheobronchial Epithelial Cells (Calu-3 and BEAS2-B), Bronchiolar–Alveolar Cells (NCI-H292 and NCI-H441), and Alveolar Type II-like Cells (A549) by Liquid Chromatography–Tandem Mass Spectrometry

(2015) Atsushi Sakamoto et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke

(2015) Diana Kuehn et al.   Jove-Journal of Visualized Experiments

Mucus as a barrier to lipophilic drugs

(2013) Hakon H. Sigurdsson et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Evaluation of blood–brain barrier and blood–cerebrospinal fluid barrier permeability of 2-phenoxy-indan-1-one derivatives using in vitro cell models

(2013) Hai-Hong Hu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Human bocavirus 1 infects commercially available primary human airway epithelium cultures productively

(2013) Xuefeng Deng et al.   JOURNAL OF VIROLOGICAL METHODS

Feasibility of a 3D human airway epithelial model to study respiratory absorption

(2013) Astrid A. Reus et al.   TOXICOLOGY IN VITRO

Inhibition of Human Respiratory Syncytial Virus Infectivity by a Dendrimeric Heparan Sulfate-Binding Peptide

(2012) Manuela Donalisio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models

(2012) Éva Hellinger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies

(2012) Jessica Verstraelen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vivo–in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems

(2012) Ursula G. Sauer et al.   TOXICOLOGY IN VITRO

The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells

(2012) Ling Ye et al.   TOXICOLOGY LETTERS

Comparison of Drug Permeabilities Across the Blood–Retinal Barrier, Blood–Aqueous Humor Barrier, and Blood–Brain Barrier

(2011) Ryotaro Toda et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Expression and differential localization of xenobiotic transporters in the rat olfactory neuro-epithelium

(2011) Nicolas Thiebaud et al.   NEUROSCIENCE LETTERS

Time- and passage-dependent characteristics of a Calu-3 respiratory epithelial cell model

(2010) Mehra Haghi et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans

(2010) T. Nakanishi et al.   DRUG METABOLISM AND DISPOSITION

In-vitro respiratory drug absorption models possess nominal functional P-glycoprotein activity

(2010) Michaela Madlova et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

(2010) Sibylle Endter et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Intestinal Absorption Mechanism of Tebipenem Pivoxil, a Novel Oral Carbapenem: Involvement of Human OATP Family in Apical Membrane Transport

(2010) Kazuhiko Kato et al.   MOLECULAR PHARMACEUTICS

Measurement and prediction of the rate and extent of drug delivery into and through the skin

(2009) LM Russell et al.   Expert Opinion on Drug Delivery

Intestinal efflux transporters and drug absorption

(2008) Teruo Murakami et al.   Expert Opinion on Drug Metabolism & Toxicology

Increasing Systemic Exposure of Methotrexate by Active Efflux Mediated by Multidrug Resistance-Associated Protein 3 (Mrp3/Abcc3)

(2008) Y. Kitamura et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS