RNA-Seq of Huntington’s disease patient myeloid cells reveals innate transcriptional dysregulation associated with proinflammatory pathway activation

Huntington’s disease biomarker progression profile identified by transcriptome sequencing in peripheral blood

(2015) Anastasios Mastrokolias et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Ballgown bridges the gap between transcriptome assembly and expression analysis

(2015) Alyssa C Frazee et al.   NATURE BIOTECHNOLOGY

Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers

(2015) Marios Politis et al.   NEUROBIOLOGY OF DISEASE

Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models

(2015) Ulrike Träger et al.   NEUROBIOLOGY OF DISEASE

Autophagy in Huntington disease and huntingtin in autophagy

(2015) Dale D.O. Martin et al.   TRENDS IN NEUROSCIENCES

Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington’s Disease T Lymphocytes

(2015) James R. C. Miller et al.   PLoS One

HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation

(2014) Ulrike Träger et al.   BRAIN

Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease

(2014) Han-Yun Hsiao et al.   HUMAN MOLECULAR GENETICS

Huntington's disease is a four-repeat tauopathy with tau nuclear rods

(2014) Marta Fernández-Nogales et al.   NATURE MEDICINE

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

(2014) Andrea Crotti et al.   NATURE NEUROSCIENCE

The Role of the Immune System in Huntington’s Disease

(2013) Gisa Ellrichmann et al.   Clinical & Developmental Immunology

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

RNA-SeQC: RNA-seq metrics for quality control and process optimization

(2012) David S. DeLuca et al.   BIOINFORMATICS

Mutant huntingtin impairs immune cell migration in Huntington disease

(2012) Wanda Kwan et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression

(2012) Andreas Weiss et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease

(2012) W. Kwan et al.   JOURNAL OF NEUROSCIENCE

Cannabinoid Receptor 2 Signaling in Peripheral Immune Cells Modulates Disease Onset and Severity in Mouse Models of Huntington's Disease

(2012) J. Bouchard et al.   JOURNAL OF NEUROSCIENCE

PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees

(2012) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Cytokine release from innate immune cells: association with diverse membrane trafficking pathways

(2011) P. Lacy et al.   BLOOD

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

What have we learned from gene expression profiles in Huntington's disease?

(2011) Tamara Seredenina et al.   NEUROBIOLOGY OF DISEASE

Overcoming natural replication barriers: differential helicase requirements

(2011) Ranjith P. Anand et al.   NUCLEIC ACIDS RESEARCH

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

Mitochondria in Huntington's disease

(2009) Maria Damiano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Beyond the brain: widespread pathology in Huntington's disease

(2009) Jorien MM van der Burg et al.   LANCET NEUROLOGY

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH