Overcoming natural replication barriers: differential helicase requirements

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

Srs2: The “Odd-Job Man” in DNA repair

(2010) Victoria Marini et al.   DNA REPAIR

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

The Full-length Saccharomyces cerevisiae Sgs1 Protein Is a Vigorous DNA Helicase That Preferentially Unwinds Holliday Junctions

(2010) Petr Cejka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae

(2010) Hengyao Niu et al.   NATURE

Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells

(2010) Guoqi Liu et al.   Nature Chemical Biology

Repeat instability as the basis for human diseases and as a potential target for therapy

(2010) Arturo López Castel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae

(2010) John A. Capra et al.   PLoS Computational Biology

Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo

(2009) Rebecca C. Burgess et al.   JOURNAL OF CELL BIOLOGY

Rep Provides a Second Motor at the Replisome to Promote Duplication of Protein-Bound DNA

(2009) Colin P. Guy et al.   MOLECULAR CELL

SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination

(2009) Alix Kerrest et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility

(2009) Irina Voineagu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption

(2009) S. Colavito et al.   NUCLEIC ACIDS RESEARCH

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

Structural Diversity and Extreme Stability of UnimolecularOxytricha novaTelomeric G-Quadruplex†

(2008) Ja Yil Lee et al.   BIOCHEMISTRY

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

Srs2 removes deadly recombination intermediates independently of its interaction with SUMO-modified PCNA

(2008) C. Le Breton et al.   NUCLEIC ACIDS RESEARCH

Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae

(2008) Alok Dhar et al.   NUCLEIC ACIDS RESEARCH

Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins

(2008) I. Voineagu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA