Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ9-tetrahydrocannabivarin (THCV), to produce CB1receptor inverse agonism symptoms of nausea in rats

Effect of low doses of cannabidiolic acid and ondansetron on LiCl-induced conditioned gaping (a model of nausea-induced behaviour) in rats

(2013) EM Rock et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidivarin is anticonvulsant in mouse and rat

(2012) AJ Hill et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiolic acid prevents vomiting inSuncus murinusand nausea-induced behaviour in rats by enhancing 5-HT1Areceptor activation

(2012) D Bolognini et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability

(2012) Lesley D. O'Brien et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation

(2011) L. De Petrocellis et al.   Acta Physiologica

Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson's disease

(2011) C García et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus

(2011) EM Rock et al.   BRITISH JOURNAL OF PHARMACOLOGY

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour

(2011) Serena Deiana et al.   PSYCHOPHARMACOLOGY

The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

(2010) Daniele Bolognini et al.   BRITISH JOURNAL OF PHARMACOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats

(2010) CL Limebeer et al.   BRITISH JOURNAL OF PHARMACOLOGY

A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents

(2010) NL Cluny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effects of cannabinoids and cannabinoid-enrichedCannabisextracts on TRP channels and endocannabinoid metabolic enzymes

(2010) Luciano De Petrocellis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Δ9-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats

(2010) Andrew J. Hill et al.   EPILEPSIA

Comparative topical anti-inflammatory activity of cannabinoids and cannabivarins

(2010) Aurelia Tubaro et al.   FITOTERAPIA

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

(2010) Joseph Tam et al.   JOURNAL OF CLINICAL INVESTIGATION

Depression-like phenotype following chronic CB1 receptor antagonism

(2010) Chad E. Beyer et al.   NEUROBIOLOGY OF DISEASE

Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice

(2009) Gernot Riedel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pleiotropic Effects of Rimonabant: Clinical Implications

(2009) Jean-Pierre Despres   CURRENT PHARMACEUTICAL DESIGN

Potential anxiogenic effects of cannabinoid CB1 receptor antagonists/inverse agonists in rats: Comparisons between AM4113, AM251, and the benzodiazepine inverse agonist FG-7142

(2009) K.S. Sink et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Melancholic features related to rimonabant

(2009) Bernardo de Mattos Viana et al.   GENERAL HOSPITAL PSYCHIATRY

Antidepressant-like effects of paroxetine are produced by lower doses than those which produce nausea

(2009) Katharine J. Tuerke et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Potential of the rat model of conditioned gaping to detect nausea produced by rolipram, a phosphodiesterase-4 (PDE4) inhibitor

(2008) Erin M. Rock et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Oral bioavailability of the novel cannabinoid CB1 antagonist AM6527: Effects on food-reinforced behavior and comparisons with AM4113

(2008) K.S. Sink et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effect of 5-HT3 antagonists and a 5-HT1A agonist on fluoxetine-induced conditioned gaping reactions in rats

(2008) Cheryl L. Limebeer et al.   PSYCHOPHARMACOLOGY

The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo

(2007) R G Pertwee et al.   BRITISH JOURNAL OF PHARMACOLOGY