Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1

Transparency in Research involving Animals: The Basel Declaration and new principles for reporting research in BJP manuscripts

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

(2015) Weili Tian et al.   FEBS LETTERS

Sequential Actions of SIRT1-RELB-SIRT3 Coordinate Nuclear-Mitochondrial Communication during Immunometabolic Adaptation to Acute Inflammation and Sepsis

(2014) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways

(2014) Candice Trocme et al.   JOURNAL OF PATHOLOGY

Pro-Inflammatory and Pro-Oxidant Status of Pancreatic Islet In Vitro Is Controlled by TLR-4 and HO-1 Pathways

(2014) Kevin Vivot et al.   PLoS One

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

(2013) Chunfen Mo et al.   ANTIOXIDANTS & REDOX SIGNALING

The Concise Guide to PHARMACOLOGY 2013/14: Nuclear Hormone Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Cardiac-specific overexpression of catalase attenuates lipopolysaccharide-induced myocardial contractile dysfunction: Role of autophagy

(2012) Subat Turdi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Trimetazidine Protects against Smoking-Induced Left Ventricular Remodeling via Attenuating Oxidative Stress, Apoptosis, and Inflammation

(2012) Xiang Zhou et al.   PLoS One

Trimetazidina na injúria de isquemia e reperfusão em cirurgia de revascularização do miocárdio

(2011) Gerez Fernandes Martins et al.   Arquivos Brasileiros de Cardiologia

Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway

(2011) M. Kitada et al.   DIABETES

Sirt1 acts in association with PPAR  to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

(2010) A. Planavila et al.   CARDIOVASCULAR RESEARCH

The sepsis seesaw: seeking a heart salve

(2009) Peter A Ward   NATURE MEDICINE

Trimetazidine Revisited: A Comprehensive Review of the Pharmacological Effects and Analytical Techniques for the Determination of Trimetazidine

(2008) A. Onay-Besikci et al.   Cardiovascular Therapeutics

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Inflammatory Pathways Are Activated during Cardiomyocyte Hypertrophy and Attenuated by Peroxisome Proliferator-activated Receptors PPARα and PPARδ

(2008) Pascal J. H. Smeets et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

(2008) Fan Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-κB and Akt pathways

(2007) Jin-Ping Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY