Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways

Pulmonary computed tomography scan findings in chronic granulomatous disease

(2013) S.A. Mahdaviani et al.   ALLERGOLOGIA ET IMMUNOPATHOLOGIA

An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD

(2013) M. Y. Zeng et al.   BLOOD

Oxidative Stress in COPD

(2013) Paul A. Kirkham et al.   CHEST

Pulmonary manifestations of chronic granulomatous disease

(2013) Seyed Alireza Mahdaviani et al.   Expert Review of Clinical Immunology

Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

(2013) Smitha Antony et al.   FREE RADICAL BIOLOGY AND MEDICINE

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

(2013) Antero Salminen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Elastase induced lung epithelial cell apoptosis and emphysema through placenta growth factor

(2013) H-H Hou et al.   Cell Death & Disease

Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice

(2012) Bing Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Oxidative Stress and Chromatin Remodeling in Chronic Obstructive Pulmonary Disease and Smoking-Related Diseases

(2012) Isaac K. Sundar et al.   ANTIOXIDANTS & REDOX SIGNALING

Epigenetic regulation of mmp-9 gene expression

(2012) Marilyne Labrie et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

Reactive Oxygen Species Produced by the NADPH Oxidase 2 Complex in Monocytes Protect Mice from Bacterial Infections

(2012) A. Pizzolla et al.   JOURNAL OF IMMUNOLOGY

Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells

(2012) Christine Deffert et al.   JOURNAL OF PATHOLOGY

Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Expression Mediates Intrinsic Airway Smooth Muscle Hypercontractility in Asthma

(2011) Amanda Sutcliffe et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis

(2011) Stephanie Carnesecchi et al.   ANTIOXIDANTS & REDOX SIGNALING

Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation

(2011) So Yong Kim et al.   IMMUNOLOGY AND CELL BIOLOGY

NOX-4 is expressed in thickened pulmonary arteries in idiopathic pulmonary fibrosis

(2011) Jean-Claude Pache et al.   NATURE MEDICINE

Differential Expression of Tissue Repair Genes in the Pathogenesis of Chronic Obstructive Pulmonary Disease

(2010) John V. Gosselink et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

(2010) Samuel Caito et al.   FASEB JOURNAL

The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis

(2010) Takashi Miyoshi et al.   IMMUNOLOGY

NADPH Oxidase-1 Plays a Crucial Role in Hyperoxia-induced Acute Lung Injury in Mice

(2009) Stéphanie Carnesecchi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9

(2009) Yuji Nakamaru et al.   FASEB JOURNAL

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Chronic Granulomatous Disease: The European Experience

(2009) J. Merlijn van den Berg et al.   PLoS One

Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) Hongwei Yao et al.   AMERICAN JOURNAL OF PATHOLOGY

p47phox Deficiency Induces Macrophage Dysfunction Resulting in Progressive Crystalline Macrophage Pneumonia

(2008) Qi Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Animal models of chronic obstructive pulmonary disease

(2008) Joanne L. Wright et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Transgenic expression of matrix metalloproteinase-9 causes adult-onset emphysema in mice associated with the loss of alveolar elastin

(2008) Robert Foronjy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4

(2008) R. F. Fernandez-Boyanapalli et al.   BLOOD

OXIDATIVE STRESS IS AN IMPORTANT COMPONENT OF AIRWAY INFLAMMATION IN MICE EXPOSED TO CIGARETTE SMOKE OR LIPOPOLYSACCHARIDE

(2008) Vincent Lagente et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Matrix Metalloproteinase Expression by Human Alveolar Macrophages in Relation to Emphysema

(2008) Alison M. Wallace et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Molecular pathogenesis of emphysema

(2008) Laimute Taraseviciene-Stewart et al.   JOURNAL OF CLINICAL INVESTIGATION

The Involvement of the Tyrosine Kinase c-Src in the Regulation of Reactive Oxygen Species Generation Mediated by NADPH Oxidase-1

(2008) Davide Gianni et al.   MOLECULAR BIOLOGY OF THE CELL

Fragments of extracellular matrix as mediators of inflammation

(2007) T ADAIRKIRK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY