Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE−/−mice and angiogenesis

Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2

(2014) Chen Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cardiovascular effects of statins, beyond lipid-lowering properties

(2014) Christos G. Mihos et al.   PHARMACOLOGICAL RESEARCH

The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Nuclear Hormone Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Anti-atherosclerotic mechanisms of statin therapy

(2013) Andrea Babelova et al.   CURRENT OPINION IN PHARMACOLOGY

Effect of a Single High Loading Dose of Rosuvastatin on Percutaneous Coronary Intervention for Acute Coronary Syndromes

(2013) Zhengzhong Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Rho and Rac Geranylgeranylation by Atorvastatin Is Critical for Preservation of Endothelial Junction Integrity

(2013) Hongbing Xiao et al.   PLoS One

Amplified Inhibition of Stellate Cell Activation Pathways by PPAR-γ, RAR and RXR Agonists

(2013) Efrat Sharvit et al.   PLoS One

Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases

(2013) C. R. Dormuth et al.   BMJ-British Medical Journal

RANTES/CCL5-induced pro-angiogenic effects depend on CCR1, CCR5 and glycosaminoglycans

(2012) N. Suffee et al.   ANGIOGENESIS

U.K. consensus statement on safe clinical prescribing of bexarotene for patients with cutaneous T-cell lymphoma

(2012) J.J. Scarisbrick et al.   BRITISH JOURNAL OF DERMATOLOGY

Retinoid X Receptor Agonists Impair Arterial Mononuclear Cell Recruitment through Peroxisome Proliferator-Activated Receptor-  Activation

(2012) M.-J. Sanz et al.   JOURNAL OF IMMUNOLOGY

Dissecting the Autocrine and Paracrine Roles of the CCR2-CCL2 Axis in Tumor Survival and Angiogenesis

(2012) Liat Izhak et al.   PLoS One

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Rosuvastatin reduced deep vein thrombosis in ApoE gene deleted mice with hyperlipidemia through non-lipid lowering effects

(2012) K.A. Patterson et al.   THROMBOSIS RESEARCH

Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation

(2011) Jeong-a Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms

(2011) Jian-an Wang et al.   ATHEROSCLEROSIS

Interplay between statins and PPARs in improving cardiovascular outcomes: a double-edged sword?

(2011) Pitchai Balakumar et al.   BRITISH JOURNAL OF PHARMACOLOGY

The PPAR-RXR Transcriptional Complex in the Vasculature

(2011) Jorge Plutzky   CIRCULATION RESEARCH

Rosuvastatin prevents proteinuria and renal inflammation in nitric oxide-deficient rats

(2011) Jose Marcos Girardi et al.   Clinics

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Interleukin-6: A Potential Target for Post-Thrombotic Syndrome

(2010) Brandon M. Wojcik et al.   ANNALS OF VASCULAR SURGERY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Statins suppress interleukin-6-induced monocyte chemo-attractant protein-1 by inhibiting Janus kinase/signal transducers and activators of transcription pathways in human vascular endothelial cells

(2010) Michihisa Jougasaki et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Angiotensin receptor blockers and angiogenesis: clinical and experimental evidence: Table 1

(2010) Lauren M. Willis et al.   CLINICAL SCIENCE

Rosuvastatin, Identified From a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer

(2010) Chunyang Wang et al.   EUROPEAN UROLOGY

Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/− mice

(2010) Jiumei Cao et al.   HUMAN MOLECULAR GENETICS

Statin Adverse Effects

(2009) Beatrice A Golomb et al.   American Journal of Cardiovascular Drugs

Simvastatin Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice

(2009) Yali Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rosuvastatin: efficacy, safety and clinical effectiveness

(2008) Handrean Soran et al.   EXPERT OPINION ON PHARMACOTHERAPY

Metabolic Switch and Hypertrophy of Cardiomyocytes following Treatment with Angiotensin II Are Prevented by AMP-activated Protein Kinase

(2008) Bettina Johanna Stuck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved Pharmacokinetic and Bioavailability Support of Drug Discovery Using Serial Blood Sampling in Mice

(2008) Sean X. Peng et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY