Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase

Review of Boceprevir and Telaprevir for the Treatment of Chronic Hepatitis C

(2016) Kyle J Wilby et al.   CANADIAN JOURNAL OF GASTROENTEROLOGY

Protease Inhibitors Block Multiple Functions of the NS3/4A Protease-Helicase during the Hepatitis C Virus Life Cycle

(2015) David R. McGivern et al.   JOURNAL OF VIROLOGY

Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors

(2014) Guanghai Jin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors

(2014) David R. McGivern et al.   GASTROENTEROLOGY

The Linker Region of NS3 Plays a Critical Role in the Replication and Infectivity of Hepatitis C Virus

(2014) A. Kohlway et al.   JOURNAL OF VIROLOGY

(+)-Vitisin A Inhibits Osteoclast Differentiation by Preventing TRAF6 Ubiquitination and TRAF6-TAK1 Formation to Suppress NFATc1 Activation

(2014) Wen-Fei Chiou et al.   PLoS One

Matrix Conditions and KLF2-Dependent Induction of Heme Oxygenase-1 Modulate Inhibition of HCV Replication by Fluvastatin

(2014) Andrea Wuestenberg et al.   PLoS One

Discovery of Hepatitis C Virus NS3 Helicase Inhibitors by a Multiplexed, High-Throughput Helicase Activity Assay Based on Graphene Oxide

(2013) Hongje Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Small-Molecule Inhibitor of Hepatitis C Virus Infectivity

(2013) Caroline O. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interaction of Hepatitis C Virus Core Protein with Janus Kinase Is Required for Efficient Production of Infectious Viruses

(2013) Choongho Lee   Biomolecules & Therapeutics

The Concise Guide to PHARMACOLOGY 2013/14: Overview

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors

(2013) Jong Yeon Hwang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Special Ingredient (VtR) Containing Oligostilbenes Isolated fromVitis thunbergiiPrevents Bone Loss in Ovariectomized Mice:In VitroandIn VivoStudy

(2013) Yu-Ling Huang et al.   Evidence-based Complementary and Alternative Medicine

Efficacy of an Interferon- and Ribavirin-Free Regimen of Daclatasvir, Asunaprevir, and BMS-791325 in Treatment-Naive Patients With HCV Genotype 1 Infection

(2013) Gregory T. Everson et al.   GASTROENTEROLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Natural Stilbenoids Isolated from Grapevine Exhibiting Inhibitory Effects against HIV-1 Integrase and Eukaryote MOS1 Transposase In Vitro Activities

(2013) Aude Pflieger et al.   PLoS One

Daclatasvir: potential role in hepatitis C

(2013) Choongho Lee   Drug Design Development and Therapy

Characterization of Resistance to the Protease Inhibitor GS-9451 in Hepatitis C Virus-Infected Patients

(2012) Hadas Dvory-Sobol et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of Grape Seed Extract on Human Norovirus GII.4 and Murine Norovirus 1 in Viral Suspensions, on Stainless Steel Discs, and in Lettuce Wash Water

(2012) Dan Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Discovery and characterization of a novel 7-aminopyrazolo[1,5-a]pyrimidine analog as a potent hepatitis C virus inhibitor

(2012) Jong Yeon Hwang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

(2012) Mi-Sun Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Telaprevir: A Hepatitis C NS3/4A Protease Inhibitor

(2012) Samuel James Matthews et al.   CLINICAL THERAPEUTICS

Selective 1O2 quenchers, oligostilbenes, from Vitis wilsonae: Structural identification and biogenetic relationship

(2012) Liyan Jiang et al.   PHYTOCHEMISTRY

Suppression of the Nrf2-Dependent Antioxidant Response by Glucocorticoids and 11β-HSD1-Mediated Glucocorticoid Activation in Hepatic Cells

(2012) Denise V. Kratschmar et al.   PLoS One

Bioavailability of resveratrol

(2011) Thomas Walle   Annals of the New York Academy of Sciences

Discovery of hepatitis C virus NS5A inhibitors as a new class of anti-HCV therapy

(2011) Choongho Lee   ARCHIVES OF PHARMACAL RESEARCH

New delivery systems to improve the bioavailability of resveratrol

(2011) Ana Cláudia Santos et al.   Expert Opinion on Drug Delivery

Anti-Inflammatory Effects of Resveratrol and Oligostilbenes fromVitis thunbergiivar.taiwanianaagainst Lipopolysaccharide-Induced Arthritis

(2011) Kun-Teng Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Interference of hepatitis C virus replication in cell culture by antisense peptide nucleic acids targeting the X-RNA

(2011) D.-G. Ahn et al.   JOURNAL OF VIRAL HEPATITIS

Vitisin B, a resveratrol tetramer, inhibits migration through inhibition of PDGF signaling and enhancement of cell adhesiveness in cultured vascular smooth muscle cells

(2011) Eng-Thaim Ong et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein

(2011) Choongho Lee et al.   VIROLOGY

A small molecule inhibits HCV replication and alters NS4B's subcellular distribution

(2010) Paul D. Bryson et al.   ANTIVIRAL RESEARCH

Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicase

(2010) Sandra Gemma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Portuguese winemaking residues as a potential source of natural anti-adenoviral agents

(2010) Ana A. Matias et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

(2010) Min Gao et al.   NATURE

Identification of a Class of HCV Inhibitors Directed Against the Nonstructural Protein NS4B

(2010) N.-J. Cho et al.   Science Translational Medicine

An antioxidant resveratrol significantly enhanced replication of hepatitis C virus

(2010) Mitsuyasu Nakamura   WORLD JOURNAL OF GASTROENTEROLOGY

Stilbenes and oligostilbenes from leaf and stem of Vitis amurensis and their cytotoxic activity

(2009) Do Thi Ha et al.   ARCHIVES OF PHARMACAL RESEARCH

Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase

(2009) Chaewoon Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Boceprevir, an NS3 Protease Inhibitor of HCV

(2009) Kenneth Berman et al.   Clinics in Liver Disease

Helicase inhibitors as specifically targeted antiviral therapy for hepatitis C

(2009) Craig A Belon et al.   Future Virology

Vitisin A suppresses LPS-induced NO production by inhibiting ERK, p38, and NF-κB activation in RAW 264.7 cells

(2009) Mi Jeong Sung et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Suppression of hepatitis C virus replication by protein kinase C-related kinase 2 inhibitors that block phosphorylation of viral RNA polymerase

(2009) S.-J. Kim et al.   JOURNAL OF VIRAL HEPATITIS

Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection

(2009) P. Gastaminza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitisin A inhibits adipocyte differentiation through cell cycle arrest in 3T3-L1 cells

(2008) Soon-hee Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Controversies in Liver Transplantation for Hepatitis C

(2008) Sandeep Mukherjee et al.   GASTROENTEROLOGY

Opposite Effects of Two Resveratrol (trans-3,5,4'-Trihydroxystilbene) Tetramers, Vitisin A and Hopeaphenol, on Apoptosis of Myocytes Isolated from Adult Rat Heart

(2008) K. Seya et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly

(2008) Y. Ma et al.   JOURNAL OF VIROLOGY

Potential of resveratrol in anticancer and anti-inflammatory therapy

(2008) Chibuike C Udenigwe et al.   NUTRITION REVIEWS

Preparative separation of oligostilbenes from Vitis thunbergii var. taiwaniana by centrifugal partition chromatography followed by Sephadex LH-20 column chromatography

(2008) Lih-Geeng Chen et al.   SEPARATION AND PURIFICATION TECHNOLOGY

3-Hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitory effect of Vitis vinifera

(2007) M. Koo et al.   FITOTERAPIA