MAF1 suppresses AKT-mTOR signaling and liver cancer through activation of PTEN transcription

Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

(2015) Nicolas Bonhoure et al.   GENES & DEVELOPMENT

Aberrant amino acid signaling promotes growth and metastasis of hepatocellular carcinomas through Rab1A-dependent activation of mTORC1 by Rab1A

(2015) Bi-Hong Xu et al.   Oncotarget

SnapShot: Hepatocellular Carcinoma

(2014) Jens U. Marquardt et al.   CANCER CELL

Rab1A Is an mTORC1 Activator and a Colorectal Oncogene

(2014) Janice D. Thomas et al.   CANCER CELL

Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance

(2014) Chi Kwan Tsang et al.   Nature Communications

Physiological Roles for mafr-1 in Reproduction and Lipid Homeostasis

(2014) Akshat Khanna et al.   Cell Reports

Maf1 Is a Novel Target of PTEN and PI3K Signaling That Negatively Regulates Oncogenesis and Lipid Metabolism

(2014) Beth M. Palian et al.   PLoS Genetics

Maf1, repressor of tRNA transcription, is involved in the control of gluconeogenetic genes in Saccharomyces cerevisiae

(2013) Ewa Morawiec et al.   GENE

Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends

(2013) Matthias S. Matter et al.   JOURNAL OF HEPATOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice

(2012) S. Menon et al.   Science Signaling

mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes

(2011) Chi Kwan Tsang et al.   CELL CYCLE

RNA polymerase III under control: repression and de-repression

(2011) Magdalena Boguta et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular Basis of RNA Polymerase III Transcription Repression by Maf1

(2010) Alessandro Vannini et al.   CELL

Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells

(2010) Boris Shor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTORC1 Directly Phosphorylates and Regulates Human MAF1

(2010) A. A. Michels et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

(2009) Yuehua Wei et al.   EMBO JOURNAL

Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

(2009) Saskia M. Brachmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CELL BIOLOGY: RNA Metabolism and Oncogenesis

(2008) D. L. Johnson et al.   SCIENCE