Maf1 Is a Novel Target of PTEN and PI3K Signaling That Negatively Regulates Oncogenesis and Lipid Metabolism

Modulation of hepatic steatosis by dietary fatty acids

(2014) Alessandra Ferramosca   WORLD JOURNAL OF GASTROENTEROLOGY

Annual Report to the Nation on the status of cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity

(2012) Christie Eheman et al.   CANCER

FoxO1 Inhibits Sterol Regulatory Element-binding Protein-1c (SREBP-1c) Gene Expression via Transcription Factors Sp1 and SREBP-1c

(2012) Xiong Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

Postprandial Hepatic Lipid Metabolism Requires Signaling through Akt2 Independent of the Transcription Factors FoxA2, FoxO1, and SREBP1c

(2011) Min Wan et al.   Cell Metabolism

Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways

(2011) Jessica L. Yecies et al.   Cell Metabolism

The Critical Role of AKT2 in Hepatic Steatosis Induced by PTEN Loss

(2010) Lina He et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular Basis of RNA Polymerase III Transcription Repression by Maf1

(2010) Alessandro Vannini et al.   CELL

Genetic control ofde novolipogenesis: role in diet-induced obesity

(2010) Maggie S. Strable et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

PTEN in Non-Alcoholic Fatty Liver Disease/Non-Alcoholic Steatohepatitis and Cancer

(2010) Marion Peyrou et al.   DIGESTIVE DISEASES

Fatty acid synthase as a potential therapeutic target in cancer

(2010) Richard Flavin et al.   Future Oncology

Expansion of Hepatic Tumor Progenitor Cells in Pten-Null Mice Requires Liver Injury and Is Reversed by Loss of AKT2

(2010) Vivian A. Galicia et al.   GASTROENTEROLOGY

mTORC1 Directly Phosphorylates and Regulates Human MAF1

(2010) A. A. Michels et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

(2010) T. Kantidakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Akt–SREBP nexus: cell signaling meets lipid metabolism

(2010) James R. Krycer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

(2009) T Mashima et al.   BRITISH JOURNAL OF CANCER

Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance

(2009) Karla F. Leavens et al.   Cell Metabolism

Cdc37 Regulates Ryk Signaling by Stabilizing the Cleaved Ryk Intracellular Domain

(2009) Jungmook Lyu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RETRACTED: Elevated tRNAiMet Synthesis Can Drive Cell Proliferation and Oncogenic Transformation

(2008) Lynne Marshall et al.   CELL

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Regulation of SREBP1c Gene Expression in Skeletal Muscle: Role of Retinoid X Receptor/Liver X Receptor and Forkhead-O1 Transcription Factor

(2008) Yasutomi Kamei et al.   ENDOCRINOLOGY

Enhanced RNA Polymerase III-dependent Transcription Is Required for Oncogenic Transformation

(2008) Sandra A. S. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex

(2008) A. Woiwode et al.   MOLECULAR AND CELLULAR BIOLOGY

CELL BIOLOGY: RNA Metabolism and Oncogenesis

(2008) D. L. Johnson et al.   SCIENCE

PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism

(2007) Manlio Vinciguerra et al.   GASTROENTEROLOGY