- Home
- Publications
- Publication Search
- Publication Details
Title
A Current Understanding of Bile Acids in Chronic Liver Disease
Authors
Keywords
cirrhosis, microbiome, bile acids, CLD, NAFLD
Journal
Journal of Clinical and Experimental Hepatology
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-08-23
DOI
10.1016/j.jceh.2021.08.017
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Impact of Genotype, Serum Bile Acids, and Surgical Biliary Diversion on Native Liver Survival in FIC1 Deficiency
- (2021) Daan B.E. van Wessel et al. HEPATOLOGY
- Ursodeoxycholic acid as a means of preventing atherosclerosis, steatosis and liver fibrosis in patients with nonalcoholic fatty liver disease
- (2021) Maria Nadinskaia et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Bile Acid Profiles Are Distinct among Patients with Different Etiologies of Chronic Liver Disease
- (2021) Chao Sang et al. JOURNAL OF PROTEOME RESEARCH
- The role of bile acids in cholestatic liver injury
- (2021) Shi-Ying Cai et al. Annals of Translational Medicine
- Effects of odevixibat on pruritus and bile acids in children with cholestatic liver disease: Phase 2 study
- (2021) Ulrich Baumann et al. Clinics and Research in Hepatology and Gastroenterology
- Evaluation of the role of bile acids and serotonin as markers of pruritus in children with chronic cholestatic liver disease
- (2021) Nehal El Koofy et al. Arab Journal of Gastroenterology
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- (2021) Claire E. Thomas et al. Cancers
- Cilofexor, a Nonsteroidal FXR Agonist, in Non‐Cirrhotic Patients with Nonalcoholic Steatohepatitis: A Phase 2 Randomized Controlled Trial
- (2020) Keyur Patel et al. HEPATOLOGY
- Modulation of bile acid profile by gut microbiota in chronic hepatitis B
- (2020) Xiaolin Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis
- (2020) Donatella Chianelli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Total bile acid-to-cholesterol ratio as a novel noninvasive marker for significant liver fibrosis and cirrhosis in patients with non-cholestatic chronic hepatitis B virus infection
- (2020) Li-Ting Yan et al. MEDICINE
- Prediagnostic Concentrations of Circulating Bile Acids and Hepatocellular Carcinoma Risk: REVEAL‐HBV and HCV Studies
- (2020) Jessica L. Petrick et al. INTERNATIONAL JOURNAL OF CANCER
- A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis
- (2020) Kris V. Kowdley et al. JOURNAL OF HEPATOLOGY
- Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study
- (2020) Philip N. Newsome et al. JOURNAL OF HEPATOLOGY
- Long-term impact of preventive UDCA therapy after transplantation for primary biliary cholangitis
- (2020) Christophe Corpechot et al. JOURNAL OF HEPATOLOGY
- Inter- and Intra-individual Variation, and Limited Prognostic Utility, of Serum Alkaline Phosphatase in a Trial of Patients With Primary Sclerosing Cholangitis
- (2020) Palak J. Trivedi et al. Clinical Gastroenterology and Hepatology
- Efficacy and Safety of Aldafermin, an Engineered FGF19 Analog, in a Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis
- (2020) Stephen A. Harrison et al. GASTROENTEROLOGY
- Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis
- (2020) Kristoffer Kjærgaard et al. JOURNAL OF HEPATOLOGY
- Gut microbiome in primary sclerosing cholangitis: A review
- (2020) Rebecca Little et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Fecal Microbiomes Distinguish Patients With Autoimmune Hepatitis From Healthy Individuals
- (2020) Jiamin Lou et al. Frontiers in Cellular and Infection Microbiology
- Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease
- (2020) Stefan Traussnigg et al. WIENER KLINISCHE WOCHENSCHRIFT
- Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
- (2020) Giljae Lee et al. Nature Communications
- Bile Acid Profiles in Primary Sclerosing Cholangitis and their Ability to Predict Hepatic Decompensation
- (2020) Omar Y. Mousa et al. HEPATOLOGY
- Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression
- (2020) Nisreen Nimer et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC
- (2019) Michael Trauner et al. HEPATOLOGY
- Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of Gamma Glutamyltransferase Normalization and Favorable Clinical Course
- (2019) Mark Deneau et al. JOURNAL OF PEDIATRICS
- NGM 282 Improves Liver Fibrosis and Histology in 12 Weeks in Patients with Nonalcoholic Steatohepatitis
- (2019) Stephen A. Harrison et al. HEPATOLOGY
- Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis
- (2019) Weihua Chen et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Ursodeoxycholic acid therapy and liver transplant-free survival in patients with primary biliary cholangitis
- (2019) Maren H. Harms et al. JOURNAL OF HEPATOLOGY
- The gut microbial influence on cholestatic liver disease
- (2019) Martin Kummen et al. LIVER INTERNATIONAL
- Alterations of gut microbiome in autoimmune hepatitis
- (2019) Yiran Wei et al. GUT
- Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study
- (2019) Michael Trauner et al. Lancet Gastroenterology & Hepatology
- CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients
- (2019) Paul J. Pockros et al. LIVER INTERNATIONAL
- Long-Term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary Cholangitis
- (2019) Christopher L. Bowlus et al. Clinical Gastroenterology and Hepatology
- Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis
- (2019) Mohammad Shadab Siddiqui et al. JOURNAL OF HEPATOLOGY
- Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
- (2019) Zobair M Younossi et al. LANCET
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non–Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers
- (2019) Michael K. Badman et al. Clinical Pharmacology in Drug Development
- Review article: therapeutic bile acids and the risks for hepatotoxicity
- (2018) K. Ashby et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Design and Endpoints for Clinical Trials in Primary Sclerosing Cholangitis
- (2018) Cyriel Y. Ponsioen et al. HEPATOLOGY
- INT-767 prevents NASH and promotes visceral fat brown adipogenesis and mitochondrial function
- (2018) Paolo Comeglio et al. JOURNAL OF ENDOCRINOLOGY
- Burden of liver disease in Europe: Epidemiology and analysis of risk factors to identify prevention policies
- (2018) Laura Pimpin et al. JOURNAL OF HEPATOLOGY
- Total Bile Acid Concentration in duodenal fluid Is a Useful Preoperative Screening Marker to Rule Out Biliary Atresia
- (2018) Tomoya Fukuoka et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Clinical, Pathologic, and Genetic Features of Neonatal Dubin-Johnson Syndrome: A Multicenter Study in Japan
- (2018) Takao Togawa et al. JOURNAL OF PEDIATRICS
- Liquid chromatography–mass spectroscopy in the diagnosis of biliary atresia in children with hyperbilirubinemia
- (2018) Jamie Golden et al. JOURNAL OF SURGICAL RESEARCH
- NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
- (2018) Stephen A Harrison et al. LANCET
- A randomised, double-blind, placebo-controlled phase 1 study of the safety, tolerability and pharmacodynamics of volixibat in overweight and obese but otherwise healthy adults: implications for treatment of non-alcoholic steatohepatitis
- (2018) Melissa Palmer et al. BMC Pharmacology & Toxicology
- The changing epidemiology of liver diseases in the Asia–Pacific region
- (2018) Martin C. S. Wong et al. Nature Reviews Gastroenterology & Hepatology
- A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters
- (2018) Mao-xu Ge et al. ACTA PHARMACOLOGICA SINICA
- Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial
- (2018) Gideon M. Hirschfield et al. JOURNAL OF HEPATOLOGY
- Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy
- (2017) Ruqi Tang et al. GUT
- Combination Therapy of All-Trans Retinoic Acid With Ursodeoxycholic Acid in Patients With Primary Sclerosing Cholangitis
- (2017) David N. Assis et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Biliary bile acids in hepatobiliary injury – What is the link?
- (2017) Peter Fickert et al. JOURNAL OF HEPATOLOGY
- nor Ursodeoxycholic acid improves cholestasis in primary sclerosing cholangitis
- (2017) Peter Fickert et al. JOURNAL OF HEPATOLOGY
- Bile Acid Synthesis Disorders in Arabs
- (2017) Abdulrahman A. Al-Hussaini et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study
- (2017) Vinod S Hegade et al. LANCET
- Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis
- (2017) Lukas Bajer et al. WORLD JOURNAL OF GASTROENTEROLOGY
- New developments in the treatment of primary biliary cholangitis – role of obeticholic acid
- (2017) Manan Jhaveri et al. Therapeutics and Clinical Risk Management
- The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
- (2016) Jérôme Boursier et al. HEPATOLOGY
- Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis
- (2016) Divya P. Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Serum Bile Acids Are Associated with Pathological Progression of Hepatitis B-Induced Cirrhosis
- (2016) Xiaoning Wang et al. JOURNAL OF PROTEOME RESEARCH
- Serum bile acids as marker for acute decompensation and acute-on-chronic liver failure in patients with non-cholestatic cirrhosis
- (2016) Thomas Horvatits et al. LIVER INTERNATIONAL
- Metabolism of glycerophospholipid, bile acid and retinol is correlated with the early outcomes of autoimmune hepatitis
- (2016) Chao Zhou et al. Molecular BioSystems
- A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis
- (2016) Frederik Nevens et al. NEW ENGLAND JOURNAL OF MEDICINE
- ACG Clinical Guideline: Primary Sclerosing Cholangitis
- (2015) Keith D Lindor et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid
- (2015) Gideon M. Hirschfield et al. GASTROENTEROLOGY
- Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States
- (2015) Robert J. Wong et al. GASTROENTEROLOGY
- Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity
- (2015) Michaela Mueller et al. JOURNAL OF HEPATOLOGY
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis
- (2015) Benjamin L. Woolbright et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Colonic inflammation and secondary bile acids in alcoholic cirrhosis
- (2014) Genta Kakiyama et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Bile acids and the gut microbiome
- (2014) Jason M. Ridlon et al. CURRENT OPINION IN GASTROENTEROLOGY
- Prospective evaluation of ursodeoxycholic acid withdrawal in patients with primary sclerosing cholangitis
- (2014) Ewa Wunsch et al. HEPATOLOGY
- Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
- (2013) Sunder Mudaliar et al. GASTROENTEROLOGY
- Modulation of the fecal bile acid profile by gut microbiota in cirrhosis
- (2013) Genta Kakiyama et al. JOURNAL OF HEPATOLOGY
- Altered profile of human gut microbiome is associated with cirrhosis and its complications
- (2013) Jasmohan S. Bajaj et al. JOURNAL OF HEPATOLOGY
- Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health
- (2012) Karin Dilger et al. JOURNAL OF HEPATOLOGY
- Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease
- (2012) Derrick E. Fouts et al. JOURNAL OF HEPATOLOGY
- Improvement of serum alkaline phosphatase to
- (2012) Said Al Mamari et al. JOURNAL OF HEPATOLOGY
- Normalization of serum bile acids after partial external biliary diversion indicates an excellent long-term outcome in children with progressive familial intrahepatic cholestasis
- (2012) Nagoud Schukfeh et al. JOURNAL OF PEDIATRIC SURGERY
- Serum bile acid levels as a predictor for the severity of liver fibrosis in patients with chronic hepatitis C
- (2012) A. Shlomai et al. JOURNAL OF VIRAL HEPATITIS
- Meta-analysis: ursodeoxycholic acid for primary sclerosing cholangitis
- (2011) C. K. Triantos et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Bile Acids Induce Inflammatory Genes in Hepatocytes
- (2011) Katryn Allen et al. AMERICAN JOURNAL OF PATHOLOGY
- Alkaline phosphatase normalization is associated with better prognosis in primary sclerosing cholangitis
- (2011) Peter P. Stanich et al. DIGESTIVE AND LIVER DISEASE
- Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells
- (2010) Hongwei He et al. HEPATOLOGY
- High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial
- (2010) Ulrich F. H. Leuschner et al. HEPATOLOGY
- Differences in presentation and progression between severe FIC1 and BSEP deficiencies
- (2010) Ludmila Pawlikowska et al. JOURNAL OF HEPATOLOGY
- A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis
- (2010) Vlad Ratziu et al. JOURNAL OF HEPATOLOGY
- High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis
- (2009) Keith D. Lindor et al. HEPATOLOGY
- Bile-acid-induced cell injury and protection
- (2009) Maria J Perez et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion
- (2008) Karan M Emerick et al. BMC GASTROENTEROLOGY
- High dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis is safe and effective
- (2008) Susan N. Cullen et al. JOURNAL OF HEPATOLOGY
- Mechanisms of Disease: inborn errors of bile acid synthesis
- (2008) Shikha S Sundaram et al. Nature clinical practice. Gastroenterology & hepatology
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search