A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters

A novel sesquiterpene glycoside from Loquat leaf alleviates oleic acid-induced steatosis and oxidative stress in HepG2 cells

(2018) Tunyu Jian et al.   BIOMEDICINE & PHARMACOTHERAPY

Cholic Acid Enhances Visceral Adiposity, Atherosclerosis and Nonalcoholic Fatty Liver Disease in Microminipigs

(2017) Sohsuke Yamada et al.   Journal of Atherosclerosis and Thrombosis

Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE 2 -Mediated Suppression of Antitumor Immunity

(2017) Tze Mun Loo et al.   Cancer Discovery

Nonalcoholic Fatty Liver Disease Is Exacerbated in High-Fat Diet-Fed Gnotobiotic Mice by Colonization with the Gut Microbiota from Patients with Nonalcoholic Steatohepatitis

(2017) Chien-Chao Chiu et al.   Nutrients

High-Fat Diet Induces Distinct Metabolic Response in Interleukin-6 and Tumor Necrosis Factor-α Knockout Mice

(2016) Xiang Chen et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice

(2016) Anuradha Rao et al.   Science Translational Medicine

Bile acid: a potential inducer of colon cancer stem cells

(2016) Lulu Farhana et al.   Stem Cell Research & Therapy

Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids

(2015) Jean-Pierre Raufman et al.   CARCINOGENESIS

Bile acid nuclear receptor FXR and digestive system diseases

(2015) Lili Ding et al.   Acta Pharmaceutica Sinica B

Intestinal transport and metabolism of bile acids

(2014) Paul A. Dawson et al.   JOURNAL OF LIPID RESEARCH

Arylsulfonylamino-Benzanilides as Inhibitors of the Apical Sodium-Dependent Bile Salt Transporter (SLC10A2)

(2013) Hong-Tao Liu et al.   MOLECULES

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

(2012) Bo Kong et al.   HEPATOLOGY

Berberine analogue IMB-Y53 improves glucose-lowering efficacy by averting cellular efflux especially P-glycoprotein efflux

(2012) Yong-Qiang Shan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Ursodeoxycholic Acid Protects Colon Cancer HCT116 Cells From Deoxycholic Acid-Induced Apoptosis by Inhibiting Apoptosome Formation

(2012) Tohru Saeki et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes

(2011) Lihong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats

(2011) K.B.M. Saiful Islam et al.   GASTROENTEROLOGY

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Computational Models for Drug Inhibition of the Human Apical Sodium-Dependent Bile Acid Transporter

(2009) Xiaowan Zheng et al.   MOLECULAR PHARMACEUTICS

Inhibition of Fibroblast Growth Factor 19 Reduces Tumor Growth by Modulating  -Catenin Signaling

(2008) R. Pai et al.   CANCER RESEARCH

Identification of the Transporters Involved in the Hepatobiliary Transport and Intestinal Efflux of Methyl 1-(3,4-Dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) Glucuronide, a Pharmacologically Active Metabolite of S-8921

(2008) S. Sakamoto et al.   DRUG METABOLISM AND DISPOSITION

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Overcome side identification in PPOP by making orifices on both layers

(2008) Zhi-hong Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS