Combination of peptides with biological, organic, and inorganic materials for synergistically enhanced diagnostics and therapeutics

Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine)

(2021) Mitsuru Naito et al.   JOURNAL OF CONTROLLED RELEASE

Cell adhesion in cancer: Beyond the migration of single cells

(2020) Michalina Janiszewska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoparticle Conjugation Stabilizes and Multimerizes β-Hairpin Peptides To Effectively Target PD-1/PD-L1 β-Sheet-Rich Interfaces

(2020) Woo-jin Jeong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Avian Influenza Virus Detection by Optimized Peptide Termination on a Boron-Doped Diamond Electrode

(2020) Teruhiko Matsubara et al.   ACS Sensors

Near-Infrared-Active Copper Bismuth Oxide Electrodes for Targeted Dissociation of Alzheimer’s β-Amyloid Aggregates

(2020) Yerin Heo et al.   ACS Applied Materials & Interfaces

Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide

(2020) Mijeong Bak et al.   Pharmaceutics

Click Reaction-Assisted Peptide Immune Checkpoint Blockade for Solid Tumor Treatment

(2020) wuyi Xiao et al.   ACS Applied Materials & Interfaces

Amplifying the chelate effect as rational approach to a DNA‐scaffolded high affinity binder for Langerin

(2020) Gunnar Bachem et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual peptide-dendrimer conjugate inhibits acetylation of transforming growth factor β-induced protein and improves survival in sepsis

(2020) Wonhwa Lee et al.   BIOMATERIALS

Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines

(2020) Anjaneyulu Dirisala et al.   Science Advances

Proton‐Conductive Melanin‐Like Fibers through Enzymatic Oxidation of a Self‐Assembling Peptide

(2020) Samala Murali Mohan Reddy et al.   ADVANCED MATERIALS

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin

(2020) Eun Jeong Park et al.   Frontiers in Cell and Developmental Biology

Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment

(2020) Yan Tan et al.   ACS Applied Materials & Interfaces

Imaging and Targeted Antibacterial Therapy Using Chimeric Antimicrobial Peptide Micelles

(2020) Seong-Cheol Park et al.   ACS Applied Materials & Interfaces

Highly Efficient Photothermal Therapy with Cell-Penetrating Peptide-Modified Bumpy Au Triangular Nanoprisms using Low Laser Power and Low Probe Dose

(2020) Minji Ha et al.   NANO LETTERS

Design of materials with supramolecular polymers

(2020) Tristan D. Clemons et al.   PROGRESS IN POLYMER SCIENCE

pH-Activatable cell penetrating peptide dimers for potent delivery of anticancer drug to triple-negative breast cancer

(2020) So Hee Nam et al.   JOURNAL OF CONTROLLED RELEASE

Intracellular delivery of immunoglobulin G at nanomolar concentrations with domain Z-fused multimeric α-helical cell penetrating peptides

(2020) Seung-Eun Chong et al.   JOURNAL OF CONTROLLED RELEASE

Report of the AAPS Guidance Forum on the FDA Draft Guidance for Industry: “Drug Products, Including Biological Products, that Contain Nanomaterials”

(2019) Jon S. B. de Vlieger et al.   AAPS Journal

Understanding Cell Penetration of Cyclic Peptides

(2019) Patrick G. Dougherty et al.   CHEMICAL REVIEWS

Peptide Sequence-Dependent Gene Expression of PEGylated Peptide/DNA Complexes

(2019) Mikiko Ueno et al.   MOLECULAR PHARMACEUTICS

In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers

(2019) Sumiyo Watanabe et al.   Nature Communications

Nose-to-brain delivery of hyaluronate – FG loop peptide conjugate for non-invasive hypoxic-ischemic encephalopathy therapy

(2019) Yun Seop Kim et al.   JOURNAL OF CONTROLLED RELEASE

Chlorin e6-Conjugated and PEGylated Immune Checkpoint Inhibitor Nanocomposites for Pulmonary Metastatic Colorectal Cancer

(2019) Young-IL Jeong et al.   ACS Omega

α-Helical cell-penetrating peptide-mediated nasal delivery of resveratrol for inhibition of epithelial-to-mesenchymal transition

(2019) Yumin Kim et al.   JOURNAL OF CONTROLLED RELEASE

Regulatory Activities of Dopamine and Its Derivatives toward Metal-Free and Metal-Induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer’s Disease

(2018) Eunju Nam et al.   ACS Chemical Neuroscience

Nanoparticle-Assisted Transcutaneous Delivery of a Signal Transducer and Activator of Transcription 3-Inhibiting Peptide Ameliorates Psoriasis-like Skin Inflammation

(2018) Jin Yong Kim et al.   ACS Nano

Site-Specific Conjugation of Polymers to Proteins

(2018) Yanjing Wang et al.   BIOMACROMOLECULES

Thiol–Ene Alginate Hydrogels as Versatile Bioinks for Bioprinting

(2018) Huey Wen Ooi et al.   BIOMACROMOLECULES

Biofunctionalized Patterned Polymer Brushes via Thiol–Ene Coupling for the Control of Cell Adhesion and the Formation of Cell Arrays

(2018) Burcu Colak et al.   BIOMACROMOLECULES

Thrombin-activatable fluorescent peptide incorporated gold nanoparticles for dual optical/computed tomography thrombus imaging

(2018) Sung-Pil Kwon et al.   BIOMATERIALS

Zwitterionic starch-based hydrogel for the expansion and “stemness” maintenance of brown adipose derived stem cells

(2018) Dianyu Dong et al.   BIOMATERIALS

Therapeutic peptides: Historical perspectives, current development trends, and future directions

(2018) Jolene L. Lau et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Block Copolymer Micelles in Nanomedicine Applications

(2018) Horacio Cabral et al.   CHEMICAL REVIEWS

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

(2018) Christopher D. Spicer et al.   CHEMICAL SOCIETY REVIEWS

Multimeric Amphipathic α-Helical Sequences for Rapid and Efficient Intracellular Protein Transport at Nanomolar Concentrations

(2018) Jae Hoon Oh et al.   Advanced Science

Block copolymer/plasmid DNA micelles postmodified with functional peptides via thiol-maleimide conjugation for efficient gene delivery into plants

(2018) Takaaki Miyamoto et al.   BIOMACROMOLECULES

Achieving Controlled Biomolecule–Biomaterial Conjugation

(2018) Christopher D. Spicer et al.   CHEMICAL REVIEWS

Peptide supramolecular materials for therapeutics

(2018) Kohei Sato et al.   CHEMICAL SOCIETY REVIEWS

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

(2018) Yijing Liu et al.   CHEMICAL SOCIETY REVIEWS

Improved Antibacterial Activity of the Marine Peptide N6 against Intracellular Salmonella Typhimurium by Conjugating with the Cell-Penetrating Peptide Tat11 via a Cleavable Linker

(2018) Zhanzhan Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Peptide-Based 68Ga-PET Radiotracer for Imaging PD-L1 Expression in Cancer

(2018) Ravindra A. De Silva et al.   MOLECULAR PHARMACEUTICS

PEG-Peptide Inhibition of Scavenger Receptor Uptake of Nanoparticles by the Liver

(2018) Rondine J. Allen et al.   MOLECULAR PHARMACEUTICS

Docetaxel-Loaded Hyaluronic Acid–Cathepsin B-Cleavable-Peptide–Gold Nanoparticles for the Treatment of Cancer

(2018) Oyuntuya Gotov et al.   MOLECULAR PHARMACEUTICS

Recent Developments and Applications of Photoconjugation Chemistry

(2018) Fan Xiao et al.   CHIMIA

Challenges and Solutions in Developing Ultrasensitive Biosensors

(2018) Yanfang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An approach for half-life extension and activity preservation of an anti-diabetic peptide drug based on genetic fusion with an albumin-binding aptide

(2017) Daejin Kim et al.   JOURNAL OF CONTROLLED RELEASE

cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors

(2017) S. Quader et al.   JOURNAL OF CONTROLLED RELEASE

The Current State of Peptide Drug Discovery: Back to the Future?

(2017) Antoine Henninot et al.   JOURNAL OF MEDICINAL CHEMISTRY

Gradient Self-Doped CuBi2O4 with Highly Improved Charge Separation Efficiency

(2017) Fuxian Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sulfated glycopeptide nanostructures for multipotent protein activation

(2017) Sungsoo S. Lee et al.   Nature Nanotechnology

Simple Protein Modification Using Zwitterionic Polymer to Mitigate the Bioactivity Loss of Conjugated Insulin

(2017) Jinbing Xie et al.   Advanced Healthcare Materials

Skin-safe photothermal therapy enabled by responsive release of acid-activated membrane-disruptive polymer from polydopamine nanoparticle upon very low laser irradiation

(2017) Rui Zhu et al.   Biomaterials Science

Cooperative Nanoparticle System for Photothermal Tumor Treatment without Skin Damage

(2016) Ji-Gang Piao et al.   ACS Applied Materials & Interfaces

Recent progress in development of siRNA delivery vehicles for cancer therapy

(2016) Hyun Jin Kim et al.   ADVANCED DRUG DELIVERY REVIEWS

In vivo and in vitro degradation of peptide YY3–36 to inactive peptide YY3–34 in humans

(2016) Signe Toräng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Reciprocal Self-Assembly of Peptide-DNA Conjugates into a Programmable Sub-10-nm Supramolecular Deoxyribonucleoprotein

(2016) Mahnseok Kye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trimeric PEG-Conjugated Exendin-4 for the Treatment of Sepsis

(2016) Wonhwa Lee et al.   BIOMACROMOLECULES

Copper(I)-Based p-Type Oxides for Photoelectrochemical and Photovoltaic Solar Energy Conversion

(2016) Ian Sullivan et al.   CHEMISTRY OF MATERIALS

Comprehensive Evaluation of CuBi2O4 as a Photocathode Material for Photoelectrochemical Water Splitting

(2016) Sean P. Berglund et al.   CHEMISTRY OF MATERIALS

Pooled screening for antiproliferative inhibitors of protein-protein interactions

(2016) Satra Nim et al.   Nature Chemical Biology

Cilia and Mucociliary Clearance

(2016) Ximena M. Bustamante-Marin et al.   Cold Spring Harbor Perspectives in Biology

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

(2016) Keisuke Katsushima et al.   Nature Communications

Current Approaches of Photothermal Therapy in Treating Cancer Metastasis with Nanotherapeutics

(2016) Lili Zou et al.   Theranostics

p-Type CuBi2O4: an easily accessible photocathodic material for high-efficiency water splitting

(2016) Dawei Cao et al.   Journal of Materials Chemistry A

Modulating protein–protein interactions: the potential of peptides

(2015) Laura Nevola et al.   CHEMICAL COMMUNICATIONS

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Chemical Reactions Directed Peptide Self-Assembly

(2015) Dnyaneshwar Rasale et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A biomimetic approach for enhancing the in vivo half-life of peptides

(2015) Sravan C Penchala et al.   Nature Chemical Biology

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles

(2015) Jeong-Yeon Kim et al.   Theranostics

Improved tumor-targeting MRI contrast agents: Gd(DOTA) conjugates of a cycloalkane-based RGD peptide

(2014) Ji-Ae Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-Term Stabilization of Maleimide–Thiol Conjugates

(2014) Shaun D. Fontaine et al.   BIOCONJUGATE CHEMISTRY

Multiplexing Natural Orientation: Oppositely Directed Self-Assembling Peptides

(2014) Woo-jin Jeong et al.   BIOMACROMOLECULES

A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules

(2014) Bibi F. Choonara et al.   BIOTECHNOLOGY ADVANCES

Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects

(2014) Sutapa Barua et al.   Nano Today

Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates

(2014) Robert P Lyon et al.   NATURE BIOTECHNOLOGY

Internal dynamics of a supramolecular nanofibre

(2014) Julia H. Ortony et al.   NATURE MATERIALS

Cyclic RGD Peptides Incorporating Cycloalkanes: Synthesis and Evaluation as PET Radiotracers for Tumor Imaging

(2014) Ji-Ae Park et al.   ACS Medicinal Chemistry Letters

Chameleon-like Self-Assembling Peptides for Adaptable Biorecognition Nanohybrids

(2013) Woo-jin Jeong et al.   ACS Nano

Directed Self-Assembly of Nanoparticles for Nanomotors

(2013) Bin Dong et al.   ACS Nano

Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

(2013) Nicolas Bertrand et al.   ADVANCED DRUG DELIVERY REVIEWS

Hyperacute direct thrombus imaging using computed tomography and gold nanoparticles

(2013) Dong-Eog Kim et al.   ANNALS OF NEUROLOGY

Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles

(2013) Maoquan Chu et al.   BIOMATERIALS

Oral delivery of an anti-diabetic peptide drug via conjugation and complexation with low molecular weight chitosan

(2013) Sukyung Ahn et al.   JOURNAL OF CONTROLLED RELEASE

Copper Sulfide Nanoparticles As a New Class of Photoacoustic Contrast Agent for Deep Tissue Imaging at 1064 nm

(2012) Geng Ku et al.   ACS Nano

Bio-Inspired Design and Potential Biomedical Applications of a Novel Class of High-Affinity Peptides

(2012) Sunghyun Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT

(2012) Yang Zhou et al.   Theranostics

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

DNA as a Molecular Ruler: Interrogation of a Tandem SH2 Domain with Self-Assembled, Bivalent DNA-Peptide Complexes

(2011) Hendrik Eberhard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natriuretic peptide metabolism, clearance and degradation

(2011) Lincoln R. Potter   FEBS Journal

Spontaneous Vesicle Self-Assembly: A Mesoscopic View of Membrane Dynamics

(2011) Julian C Shillcock   LANGMUIR

Combination Self-Assembly of β-Sheet Peptides and Carbon Nanotubes: Functionalizing Carbon Nanotubes with Bioactive β-Sheet Block Copolypeptides

(2011) Woo-jin Jeong et al.   MACROMOLECULAR BIOSCIENCE

Noninvasive, Transient and Selective Blood-Brain Barrier Opening in Non-Human Primates In Vivo

(2011) Fabrice Marquet et al.   PLoS One

Peptide-Based Probes for Targeted Molecular Imaging

(2010) Seulki Lee et al.   BIOCHEMISTRY

Peptides and Peptide Hormones for Molecular Imaging and Disease Diagnosis

(2010) Seulki Lee et al.   CHEMICAL REVIEWS

Bioresponsive peptide–inorganic hybrid nanomaterials

(2010) Daniel Aili et al.   CHEMICAL SOCIETY REVIEWS

Stimulus responsive peptide based materials

(2010) Dennis W. P. M. Löwik et al.   CHEMICAL SOCIETY REVIEWS

Advances in Metal-Based Probes for MR Molecular Imaging Applications

(2010) E. Terreno et al.   CURRENT MEDICINAL CHEMISTRY

Molecular imaging in cancer treatment

(2010) Mark H. Michalski et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics

(2010) Su Young Chae et al.   JOURNAL OF CONTROLLED RELEASE

Revisiting an old friend: manganese-based MRI contrast agents

(2010) Dipanjan Pan et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Protein and peptide drug delivery: Oral approaches

(2009) Jessy Shaji et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Clustering and Internalization of Integrin αvβ3 With a Tetrameric RGD-synthetic Peptide

(2009) Sancey Lucie et al.   MOLECULAR THERAPY

Pharmacokinetics and pharmacodynamics of exenatide following alternate routes of administration

(2008) Bronislava R. Gedulin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Albiglutide, a Long-Acting Glucagon-Like Peptide-1 Mimetic, in Patients with Type 2 Diabetes

(2008) Jessica E. Matthews et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Protein denaturation by urea: Slash and bond

(2008) P. J. Rossky   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA