Simple Protein Modification Using Zwitterionic Polymer to Mitigate the Bioactivity Loss of Conjugated Insulin

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates

(2015) Danny Hung-Chieh Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity

(2015) Peng Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zwitterionic Poly(carboxybetaine)-based Cationic Liposomes for Effective Delivery of Small Interfering RNA Therapeutics without Accelerated Blood Clearance Phenomenon

(2015) Yan Li et al.   Theranostics

Therapeutic Protein–Polymer Conjugates: Advancing Beyond PEGylation

(2014) Emma M. Pelegri-O’Day et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The use of the mechanical microenvironment of phospholipid polymer hydrogels to control cell behavior

(2013) Haruka Oda et al.   BIOMATERIALS

Site-specific conjugation of RAFT polymers to proteins via expressed protein ligation

(2013) Yan Xia et al.   CHEMICAL COMMUNICATIONS

PEGylated insulin Lispro, (LY2605541)-a new basal insulin analogue

(2013) T. M. Caparrotta et al.   DIABETES OBESITY & METABOLISM

Softer Zwitterionic Nanogels for Longer Circulation and Lower Splenic Accumulation

(2012) Lei Zhang et al.   ACS Nano

Superhydrophilic Zwitterionic Polymers Stabilize Liposomes

(2012) Zhiqiang Cao et al.   LANGMUIR

Super-hydrophilic zwitterionic poly(carboxybetaine) and amphiphilic non-ionic poly(ethylene glycol) for stealth nanoparticles

(2012) Zhiqiang Cao et al.   Nano Today

Poly(zwitterionic)protein conjugates offer increased stability without sacrificing binding affinity or bioactivity

(2011) Andrew J. Keefe et al.   Nature Chemistry

Relieving PEGylation

(2011) Matthew C. Parrott et al.   Nature Chemistry

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of hydrophilic polymer conjugation on heat-induced conformational changes in a protein

(2010) Ji-Hun Seo et al.   Acta Biomaterialia

In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation

(2010) W. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications

(2009) Shaoyi Jiang et al.   ADVANCED MATERIALS

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonnatural Amino Acids for Site-Specific Protein Conjugation

(2009) Albert J. de Graaf et al.   BIOCONJUGATE CHEMISTRY

Functionalizable and ultra stable nanoparticles coated with zwitterionic poly(carboxybetaine) in undiluted blood serum

(2009) Wei Yang et al.   BIOMATERIALS

Enzymatic activity and thermal stability of PEG-α-chymotrypsin conjugates

(2009) José A. Rodríguez-Martínez et al.   BIOTECHNOLOGY LETTERS

The Impact of PEGylation on Biological Therapies

(2008) Francesco M Veronese et al.   BIODRUGS

Suppression of Protein Adsorption on a Charged Phospholipid Polymer Interface

(2008) Yan Xu et al.   BIOMACROMOLECULES