Immunopharmacology in Vernal Keratoconjunctivitis: Current and Future Perspectives

Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma

(2021) Ashish Bansal et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Vernal keratoconjunctivitis: An update

(2021) Daniele Giovanni Ghiglioni et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

A contemporary look at allergic conjunctivitis

(2020) Pascale Dupuis et al.   Allergy Asthma and Clinical Immunology

Ocular surface disease associated with dupilumab treatment for atopic diseases

(2020) Canan Asli Utine et al.   Ocular Surface

Management of corneal complications in vernal keratoconjunctivitis: A review

(2020) Sepehr Feizi et al.   Ocular Surface

Management of ocular allergy

(2019) Andrea Leonardi et al.   ALLERGY

Conjunctivitis in dupilumab clinical trials

(2019) B. Akinlade et al.   BRITISH JOURNAL OF DERMATOLOGY

Prevalence of vernal keratoconjunctivitis and its associated factors among children in Gambella town, southwest Ethiopia, June 2018

(2019) Abiy Maru Alemayehu et al.   PLoS One

Amelioration of conjunctival giant papillae by dupilumab in patients with atopic keratoconjunctivitis

(2019) Ken Fukuda et al.   Journal of Allergy and Clinical Immunology-In Practice

Higher mortality of adults with asthma: A 15-year follow-up of a population-based cohort

(2018) R. E. Lemmetyinen et al.   ALLERGY

Daily allergic multimorbidity in rhinitis using mobile technology: A novel concept of the MASK study

(2018) J. Bousquet et al.   ALLERGY

The stem cell factor-stimulated melanogenesis in human melanocytes can be abrogated by interrupting the phosphorylation of MSK1: evidence for involvement of the p38/MSK1/CREB/MITF axis

(2018) Takao Niwano et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Rapamycin attenuates Th2-driven experimental allergic conjunctivitis

(2018) Soojung Shin et al.   CLINICAL IMMUNOLOGY

Omalizumab as single-dose therapy for vernal keratoconjunctivitis

(2018) Rachel Simpson et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Superficial Keratectomy and Amniotic Membrane Patch in the Treatment of Corneal Plaque of Vernal Keratoconjunctivitis

(2018) L. Pelegrin et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge

(2018) Shuying Yi et al.   Nature Communications

A Randomized, Controlled Trial of Cyclosporine A Cationic Emulsion in Pediatric Vernal Keratoconjunctivitis: The VEKTIS Study

(2018) Andrea Leonardi et al.   OPHTHALMOLOGY

Vernal Keratoconjunctivitis

(2018) Deepali Singhal et al.   SURVEY OF OPHTHALMOLOGY

Rapamycin Nano-Micelle Ophthalmic Solution Reduces Corneal Allograft Rejection by Potentiating Myeloid-Derived Suppressor Cells' Function

(2018) Chao Wei et al.   Frontiers in Immunology

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial

(2017) Andrew Blauvelt et al.   LANCET

Prevalence and clinical features of adult atopic dermatitis in tertiary hospitals of China

(2017) Xin Wang et al.   MEDICINE

Multi-morbidities of allergic rhinitis in adults: European Academy of Allergy and Clinical Immunology Task Force Report

(2017) C. Cingi et al.   Clinical and Translational Allergy

Long-Term Safety and Efficacy of Topical Cyclosporine in 156 Children with Vernal Keratoconjunctivitis

(2017) N. Pucci et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Dry Eye Disease and Allergic Conditions: A Korean Nationwide Population-Based Study

(2016) Minkyeong Kim et al.   American Journal of Rhinology & Allergy

Reslizumab: First Global Approval

(2016) Anthony Markham   DRUGS

Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm

(2016) NikhilS Gokhale   INDIAN JOURNAL OF OPHTHALMOLOGY

A histamine-independent itch pathway is required for allergic ocular itch

(2016) Cheng-Chiu Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

(2016) Eric L. Simpson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TRPV1 Antagonist Suppresses Allergic Conjunctivitis in a Murine Model

(2016) Ji Young Kwon et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Efficacy and safety of topical cyclosporine A 0.05% in vernal keratoconjunctivitis

(2016) OE Yücel et al.   SINGAPORE MEDICAL JOURNAL

Prevalence and associated factors of vernal keratoconjunctivitis among children in Gondar city, Northwest Ethiopia

(2016) Dereje Hayilu et al.   BMC Ophthalmology

An Update on the Therapeutic Approach to Vernal Keratoconjunctivitis

(2016) Susanna Esposito et al.   PEDIATRIC DRUGS

Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis

(2016) Xiaofen Zheng et al.   Journal of Ophthalmology

Omalizumab Treatment of Vernal Keratoconjunctivitis

(2016) Enrico Heffler et al.   JAMA Ophthalmology

A randomized trial of benralizumab, an antiinterleukin 5 receptor α monoclonal antibody, after acute asthma

(2015) Richard M. Nowak et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

The C-C chemokine receptor 6 (CCR6) is crucial for Th2-driven allergic conjunctivitis

(2015) So-Hyang Chung et al.   CLINICAL IMMUNOLOGY

Epidemiology of allergic conjunctivitis

(2015) Andrea Leonardi et al.   Current Opinion in Allergy and Clinical Immunology

Corneal complications of vernal keratoconjunctivitis

(2015) Abraham Solomon   Current Opinion in Allergy and Clinical Immunology

Characterization of the relationship between dose and blood eosinophil response following subcutaneous administration of mepolizumab

(2015) Isabelle J. Pouliquen et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

A comprehensive review on vernal keratoconjunctivitis with emphasis on proteomics

(2015) Lolly Pattnaik et al.   LIFE SCIENCES

Dry Eye in Vernal Keratoconjunctivitis

(2015) Edoardo Villani et al.   MEDICINE

Ocular transient receptor potential channel function in health and disease

(2015) Peter S. Reinach et al.   BMC Ophthalmology

The role of TRPV1 in the CD4+ T cell-mediated inflammatory response of allergic rhinitis

(2015) Ramachandran Samivel et al.   Oncotarget

Prevalence and risk factors of dry eye disease in a British female cohort

(2014) Jelle Vehof et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

CCL20/MIP-3 alpha mRNA expression in the conjunctival epithelium of normal individuals and patients with vernal keratoconjunctivitis

(2014) Noriko Inada et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Immunogenetic investigation in vernal keratoconjunctivitis

(2014) Anna Maria Zicari et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Vernal keratoconjunctivitis: A severe allergic eye disease with remodeling changes

(2014) Pakit Vichyanond et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

An algorithm for the management of allergic conjunctivitis

(2013) Leonard Bielory et al.   ALLERGY AND ASTHMA PROCEEDINGS

Vernal Keratoconjunctivitis-like Disease in Adults

(2013) Andrea Leonardi et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Perennial is More Effective than Preseasonal Subcutaneous Immunotherapy in the Treatment of Seasonal Allergic Rhinoconjunctivitis

(2013) Damian Tworek et al.   American Journal of Rhinology & Allergy

An essential role for dendritic cells in vernal keratoconjunctivitis: analysis by laser scanning confocal microscopy

(2013) M. Liu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Tear Cytokine Levels in Vernal Keratoconjunctivitis

(2013) Merih Oray et al.   CORNEA

Use of Cyclosporine A and Tacrolimus in Treatment of Vernal Keratoconjunctivitis

(2013) Pakit Vichyanond et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Demographic and clinical profile of vernal keratoconjunctivitis at a tertiary eye care center in India

(2013) UjwalaS Saboo et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

Severe vernal keratoconjunctivitis successfully treated with subcutaneous omalizumab

(2013) Timothy A. de Klerk et al.   JOURNAL OF AAPOS

Ocular allergy: recognizing and diagnosing hypersensitivity disorders of the ocular surface

(2012) A. Leonardi et al.   ALLERGY

Management, Clinical Outcomes, and Complications of Shield Ulcers in Vernal Keratoconjunctivitis

(2012) Jagadesh C. Reddy et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Blocking CCR7 at the Ocular Surface Impairs the Pathogenic Contribution of Dendritic Cells in Allergic Conjunctivitis

(2012) Simona Schlereth et al.   AMERICAN JOURNAL OF PATHOLOGY

Vernal keratoconjunctivitis: an update

(2012) Stefan De Smedt et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Molecular immunology of allergic conjunctivitis

(2012) Murat T. Irkec et al.   Current Opinion in Allergy and Clinical Immunology

Oral cyclosporine therapy for refractory severe vernal keratoconjunctivitis

(2012) NikhilS Gokhale et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

Vernal Keratoconjunctivitis in School Children in Rwanda

(2012) Stefan K. De Smedt et al.   OPHTHALMOLOGY

TSLP Expression: Cellular Sources, Triggers, and Regulatory Mechanisms

(2012) Toshiro Takai   ALLERGOLOGY INTERNATIONAL

Supratarsal injection of triamcinolone acetonide and childhood allergic keratoconjunctivitis

(2012) Sonia Zaouali et al.   INTERNATIONAL OPHTHALMOLOGY

Immunotherapy for allergic rhinitis

(2011) S. M. Walker et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Sublingual immunotherapy for allergic conjunctivitis: Cochrane systematic review and meta-analysis

(2011) M. A. Calderon et al.   CLINICAL AND EXPERIMENTAL ALLERGY

A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells

(2011) F. Zhang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Long-term clinical and immunological effects of allergen immunotherapy

(2011) Aarif O. Eifan et al.   Current Opinion in Allergy and Clinical Immunology

Ocular allergy

(2011) Mitchell H. Friedlaender   Current Opinion in Allergy and Clinical Immunology

Epidemiology of allergic conjunctivitis

(2011) Nelson Rosario et al.   Current Opinion in Allergy and Clinical Immunology

Topical 0.005% tacrolimus eye drop for refractory vernal keratoconjunctivitis

(2011) A Kheirkhah et al.   EYE

Topical cyclosporine prevents seasonal recurrences of vernal keratoconjunctivitis in a randomized, double-masked, controlled 2-year study

(2011) Alessandro Lambiase et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Conjunctival Goblet Cell Secretion Stimulated by Leukotrienes Is Reduced by Resolvins D1 and E1 To Promote Resolution of Inflammation

(2011) Darlene A. Dartt et al.   JOURNAL OF IMMUNOLOGY

Intravenous immunoglobulin (IVIg) in the management of severe refractory vernal keratoconjunctivitis

(2010) L. Derriman et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

MAP4K3 regulates body size and metabolism in Drosophila

(2010) Boris Bryk et al.   DEVELOPMENTAL BIOLOGY

Atopic Dermatitis and Keratoconjunctivitis

(2010) Brett Bielory et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Eosinophils and Th2 immunity: contemporary insights

(2010) Lisa A Spencer et al.   IMMUNOLOGY AND CELL BIOLOGY

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma

(2010) William W. Busse et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen immunotherapy

(2010) Anthony J. Frew   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergen immunotherapy: A practice parameter third update

(2010) Linda Cox et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Randomized, Placebo-Controlled Clinical Trial of Tacrolimus Ophthalmic Suspension 0.1% in Severe Allergic Conjunctivitis

(2010) Yuichi Ohashi et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Ocular surface disease: A case of vernal keratoconjunctivitis

(2010) DeGaulle I. Chigbu et al.   Contact Lens & Anterior Eye

Cytokines, matrix metalloproteases, angiogenic and growth factors in tears of normal subjects and vernal keratoconjunctivitis patients

(2009) A. Leonardi et al.   ALLERGY

Immunomodulation of Allergic Disease

(2009) David H. Broide   Annual Review of Medicine

Unilateral pseudogerontoxon

(2009) Scott A Read et al.   Clinical and Experimental Optometry

Prospective, Multicenter Demographic and Epidemiological Study on Vernal Keratoconjunctivitis: A Glimpse of Ocular Surface in Italian Population

(2009) Alessandro Lambiase et al.   OPHTHALMIC EPIDEMIOLOGY

The management of allergic eye diseases in primary eye care

(2009) DeGaulle I. Chigbu   Contact Lens & Anterior Eye

Vernal keratoconjunctivitis: a major review

(2008) Sunil Kumar   ACTA OPHTHALMOLOGICA

Prevalence of vernal keratoconjunctivitis: a rare disease?

(2008) D Bremond-Gignac et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Combination of omalizumab and specific immunotherapy is superior to immunotherapy in patients with seasonal allergic rhinoconjunctivitis and co-morbid seasonal allergic asthma

(2008) M. V. Kopp et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Allergy and the eye

(2008) A. Leonardi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Efficacy of topical cyclosporin A 0.05% in conjunctival impression cytology specimens and clinical findings of severe vernal keratoconjunctivitis in children

(2008) Ugur Keklikci et al.   JAPANESE JOURNAL OF OPHTHALMOLOGY

Anti–IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels

(2008) Miguel L. Stein et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The pathophysiology of ocular allergy: A review

(2008) De Gaulle I. Chigbu   Contact Lens & Anterior Eye