E-Selectin-Dependent Inflammation and Lipolysis in Adipose Tissue Exacerbate Steatosis-to-NASH Progression via S100A8/9

Kupffer cell restoration after partial hepatectomy is mainly driven by local cell proliferation in IL-6-dependent autocrine and paracrine manners

(2021) Yeni Ait Ahmed et al.   Cellular & Molecular Immunology

Epidemiological feature of NAFLD from 1999 to 2018 in China

(2020) Jianghua Zhou et al.   HEPATOLOGY

The endothelial function biomarker soluble E‐selectin is associated with nonalcoholic fatty liver disease

(2020) Nynke Simons et al.   LIVER INTERNATIONAL

Protective and Detrimental Roles of p38α MAPK in Different Stages of Nonalcoholic Fatty Liver Disease

(2020) Seonghwan Hwang et al.   HEPATOLOGY

Differential production of insulin-like growth factor-binding proteins in liver fibrosis progression

(2020) Moisés Martínez-Castillo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

L-Selectin/CD62L Is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men

(2020) Hannah K. Drescher et al.   Cells

Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?

(2020) Patricia Rada et al.   Cell Death & Disease

Hepatokines and adipokines in NASH-related hepatocellular carcinoma

(2020) Ozlem Kucukoglu et al.   JOURNAL OF HEPATOLOGY

Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C‐C Motif) Receptor 2‐Positive Macrophages and Lipolysis

(2019) Seung‐Jin Kim et al.   HEPATOLOGY

Micro RNA ‐223 ameliorates nonalcoholic steatohepatitis and cancer by targeting multiple inflammatory and oncogenic genes in hepatocytes

(2019) Yong He et al.   HEPATOLOGY

L-selectin: A Major Regulator of Leukocyte Adhesion, Migration and Signaling

(2019) Aleksandar Ivetic et al.   Frontiers in Immunology

Interleukin‐22 ameliorates neutrophil‐driven nonalcoholic steatohepatitis through multiple targets

(2019) Seonghwan Hwang et al.   HEPATOLOGY

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Triggering and resolution of inflammation in NASH

(2018) Susanne Schuster et al.   Nature Reviews Gastroenterology & Hepatology

S100A8/A9 in Inflammation

(2018) Siwen Wang et al.   Frontiers in Immunology

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

(2017) Mitchell Bijnen et al.   GUT

Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease

(2017) Chris Estes et al.   HEPATOLOGY

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes

(2017) Michael J. Kraakman et al.   JOURNAL OF CLINICAL INVESTIGATION

IGFBP-1 and IGF-I as markers for advanced fibrosis in NAFLD – a pilot study

(2017) Hannes Hagström et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

S100A8/A9: From basic science to clinical application

(2016) Monika Pruenster et al.   PHARMACOLOGY & THERAPEUTICS

Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies

(2015) Siddharth Singh et al.   Clinical Gastroenterology and Hepatology

Association of Adipose Tissue Inflammation With Histologic Severity of Nonalcoholic Fatty Liver Disease

(2015) Johannie du Plessis et al.   GASTROENTEROLOGY

Short- or long-term high-fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: An important role for CXCL1

(2015) Binxia Chang et al.   HEPATOLOGY

Nonalcoholic Steatohepatitis: Involvement of the Telomerase and Proinflammatory Mediators

(2015) Rim Serhal et al.   Biomed Research International

Regulation of adipocyte lipolysis

(2014) Gema Frühbeck et al.   NUTRITION RESEARCH REVIEWS

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: A critical role for E-selectin

(2013) Adeline Bertola et al.   HEPATOLOGY

S100A8 and S100A9: DAMPs at the Crossroads between Innate Immunity, Traditional Risk Factors, and Cardiovascular Disease

(2013) Alexandru Schiopu et al.   MEDIATORS OF INFLAMMATION

Non-alcoholic steatohepatitis in morbidly obese patients

(2013) Albert Tran et al.   Clinics and Research in Hepatology and Gastroenterology

β3-Adrenergic Receptor Stimulation Induces E-Selectin-mediated Adipose Tissue Inflammation

(2012) Rachel J. Roth Flach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease

(2011) A. D. Lake et al.   DRUG METABOLISM AND DISPOSITION

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(2011) Victoria Catalan et al.   MOLECULAR MEDICINE

Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis

(2010) Robert C Huebert et al.   LABORATORY INVESTIGATION

Nonalcoholic Fatty Liver Disease: The Pathogenetic Roles of Insulin Resistance and Adipocytokines

(2009) Stergios Polyzos et al.   CURRENT MOLECULAR MEDICINE

Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance

(2009) Yusuf Yilmaz et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal

(2009) Naim Alkhouri et al.   Expert Review of Gastroenterology & Hepatology

Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

(2009) Per Björk et al.   PLOS BIOLOGY

Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids

(2008) Braedon McDonald et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease

(2008) Harmeet Malhi et al.   SEMINARS IN LIVER DISEASE