Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer

Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

(2020) Wenhua Liang et al.   LANCET ONCOLOGY

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China

(2020) L. Zhang et al.   ANNALS OF ONCOLOGY

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Covid-19 transmission, outcome and associated risk factors in cancer patients at the first month of the pandemic in a Spanish hospital in Madrid

(2020) J. Rogado et al.   Clinical & Translational Oncology

SARS-CoV-2: Combating Coronavirus Emergence

(2020) Rachel L. Graham et al.   IMMUNITY

Anticoagulant and antiarrhythmic effects of heparin in the treatment of COVID‐19 patients

(2020) Francisco Sandro Menezes‐Rodrigues et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cancer and COVID-19: what do we really know?

(2020) Philip M Poortmans et al.   LANCET

Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19

(2020) Jiewen Fu et al.   MOLECULAR BIOLOGY REPORTS

Site-specific glycan analysis of the SARS-CoV-2 spike

(2020) Yasunori Watanabe et al.   SCIENCE

Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System

(2020) Vikas Mehta et al.   Cancer Discovery

SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China

(2020) Jing Yu et al.   JAMA Oncology

Heparin as a therapy for COVID-19: current evidence and future possibilities

(2020) Joseph A. Hippensteel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

(2020) Bette Korber et al.   CELL

Discovering small-molecule therapeutics against SARS-CoV-2

(2020) Vaibhav Tiwari et al.   DRUG DISCOVERY TODAY

Angiotensin‐converting enzyme 2: The old door for new severe acute respiratory syndrome coronavirus 2 infection

(2020) Heng Wee Tan et al.   REVIEWS IN MEDICAL VIROLOGY

Comprehensive Analysis of the Glycan Complement of SARS-CoV-2 Spike Proteins Using Signature Ions-Triggered Electron-Transfer/Higher-Energy Collisional Dissociation (EThcD) Mass Spectrometry

(2020) Dongxia Wang et al.   ANALYTICAL CHEMISTRY

Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions

(2020) So Young Kim et al.   ANTIVIRAL RESEARCH

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

(2020) Thomas Mandel Clausen et al.   CELL

Tracking SARS-CoV-2 in Sewage: Evidence of Changes in Virus Variant Predominance during COVID-19 Pandemic

(2020) Javier Martin et al.   Viruses-Basel

Variations in SARS-CoV-2 Spike Protein Cell Epitopes and Glycosylation Profiles During Global Transmission Course of COVID-19

(2020) Wenxin Xu et al.   Frontiers in Immunology

Unfractionated Heparin in SARS-CoV-2 Pneumonia: Ischemic Stroke Case Report

(2020) Aslan Efendizade et al.   Frontiers in Neurology

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?

(2019) Cagno et al.   Viruses-Basel

3-O -Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake

(2019) Jing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Correlation Between the Immune and Epithelial-Mesenchymal Transition Signatures Suggests Potential Therapeutic Targets and Prognosis Prediction Approaches in Kidney Cancer

(2018) Jiayu Liang et al.   Scientific Reports

A mutant-cell library for systematic analysis of heparan sulfate structure–function relationships

(2018) Hong Qiu et al.   NATURE METHODS

Heparan Sulfate Microarray Reveals That Heparan Sulfate–Protein Binding Exhibits Different Ligand Requirements

(2017) Chengli Zong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Glycosaminoglycans and infection

(2016) Pyong Woo Park   Frontiers in Bioscience-Landmark

Integrated Approach to Identify Heparan Sulfate Ligand Requirements of Robo1

(2016) Chengli Zong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing the impact of GFP tagging on Robo1-heparin interaction

(2014) Fuming Zhang et al.   GLYCOCONJUGATE JOURNAL

Human Coronavirus NL63 Utilizes Heparan Sulfate Proteoglycans for Attachment to Target Cells

(2014) A. Milewska et al.   JOURNAL OF VIROLOGY

Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans

(2013) Fuming Zhang et al.   BIOCHIMIE

Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia

(2013) Bing Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Heparan sulfate 3-O-sulfation: A rare modification in search of a function

(2013) Bryan E. Thacker et al.   MATRIX BIOLOGY

Quantitative Phosphoproteomics Analysis Reveals Broad Regulatory Role of Heparan Sulfate on Endothelial Signaling

(2013) Hong Qiu et al.   MOLECULAR & CELLULAR PROTEOMICS

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity

(2012) E. Condac et al.   GLYCOBIOLOGY

Heparan Sulfate Facilitates FGF and BMP Signaling to Drive Mesoderm Differentiation of Mouse Embryonic Stem Cells

(2012) Daniel C. Kraushaar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparin-induced Leukocytosis Requires 6-O-Sulfation and Is Caused by Blockade of Selectin- and CXCL12 Protein-mediated Leukocyte Trafficking in Mice

(2011) Siyuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple mechanisms for exogenous heparin modulation of vascular endothelial growth factor activity

(2010) Errol Wijelath et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Heparan Sulfate Is Required for Embryonic Stem Cells to Exit from Self-renewal

(2009) Daniel C. Kraushaar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sulfated K5 Escherichia coli polysaccharide derivatives: A novel class of candidate antiviral microbicides

(2009) Marco Rusnati et al.   PHARMACOLOGY & THERAPEUTICS

Cleavage of Group 1 Coronavirus Spike Proteins: How Furin Cleavage Is Traded Off against Heparan Sulfate Binding upon Cell Culture Adaptation

(2008) C. A. M. de Haan et al.   JOURNAL OF VIROLOGY

Surfen, a small molecule antagonist of heparan sulfate

(2008) M. Schuksz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA