Drug repurposing against coronavirus disease 2019 (COVID-19): A review
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Drug repurposing against coronavirus disease 2019 (COVID-19): A review
Authors
Keywords
Drug repurposing, COVID-19, SARS-CoV-2, Treatment, Coronavirus, 3C-like protease
Journal
Journal of Pharmaceutical Analysis
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-09-04
DOI
10.1016/j.jpha.2021.09.001
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chemical composition and pharmacological mechanism of ephedra-glycyrrhiza drug pair against coronavirus disease 2019 (COVID-19)
- (2021) Xiaoling Li et al. Aging-US
- Natural drug sources for respiratory diseases from Fritillaria: chemical and biological analyses
- (2021) Ye Wang et al. Chinese Medicine
- Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV
- (2020) Jared S. Morse et al. CHEMBIOCHEM
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle
- (2020) Hongzhou Lu et al. JOURNAL OF MEDICAL VIROLOGY
- Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
- (2020) Abdo A. Elfiky LIFE SCIENCES
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
- (2020) Eva Schrezenmeier et al. Nature Reviews Rheumatology
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
- (2020) Emmie de Wit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites
- (2020) Si Chen et al. Viruses-Basel
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
- (2020) Canrong Wu et al. Acta Pharmaceutica Sinica B
- The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
- (2020) B. Coutard et al. ANTIVIRAL RESEARCH
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis
- (2020) George Dimopoulos et al. Cell Host & Microbe
- In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
- (2020) Xueting Yao et al. CLINICAL INFECTIOUS DISEASES
- Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine
- (2020) Zahra Sahraei et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Identification of potential molecules against COVID-19 main protease through structure-guided virtual screening approach
- (2020) Lovika Mittal et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Potential anti-viral activity of approved repurposed drug against main protease of SARS-CoV-2: an in silico based approach
- (2020) Saurov Mahanta et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Repurposing approved drugs as inhibitors of SARS-CoV-2 S-protein from molecular modeling and virtual screening
- (2020) Osmair Vital de Oliveira et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Identification of bioactive molecules from tea plant as SARS-CoV-2 main protease inhibitors
- (2020) Vijay Kumar Bhardwaj et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Deployment of convalescent plasma for the prevention and treatment of COVID-19
- (2020) Evan M. Bloch et al. JOURNAL OF CLINICAL INVESTIGATION
- Treatment options for COVID-19: The reality and challenges
- (2020) Shio-Shin Jean et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
- An overview of COVID-19
- (2020) Yu Shi et al. Journal of Zhejiang University-SCIENCE B
- Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
- (2020) Yeming Wang et al. LANCET
- COVID-19: consider cytokine storm syndromes and immunosuppression
- (2020) Puja Mehta et al. LANCET
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: A multicenter, prospective, randomized controlled trial
- (2020) Ke Hu et al. PHYTOMEDICINE
- Effectiveness of convalescent plasma therapy in severe COVID-19 patients
- (2020) Kai Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In Silico Discovery of Candidate Drugs against Covid-19
- (2020) Claudia Cava et al. Viruses-Basel
- Treatment efficacy analysis of traditional Chinese medicine for novel coronavirus pneumonia (COVID-19): an empirical study from Wuhan, Hubei Province, China
- (2020) Erdan Luo et al. Chinese Medicine
- Current perspectives on Coronavirus 2019 (COVID‐19) and cardiovascular disease: A white paper by the JAHA editors
- (2020) Ajay K. Gupta et al. Journal of the American Heart Association
- Potential anti‐SARS‐CoV‐2 drug candidates identified through virtual screening of the ChEMBL database for compounds that target the main coronavirus protease
- (2020) Motonori Tsuji FEBS Open Bio
- Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients
- (2020) Yonggang Zhou et al. National Science Review
- Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
- (2020) Cynthia Liu et al. ACS Central Science
- Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
- (2020) Yadi Zhou et al. Cell Discovery
- Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options
- (2020) Erin K McCreary et al. Open Forum Infectious Diseases
- Network pharmacology-based analysis of the role of traditional Chinese herbal medicines in the treatment of COVID-19
- (2020) Shengwei Yu et al. Annals of Palliative Medicine
- The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
- (2020) Leon Caly et al. ANTIVIRAL RESEARCH
- COVID-19 treatment: Combining anti-inflammatory and antiviral therapeutics using a network-based approach
- (2020) Feixiong Cheng et al. CLEVELAND CLINIC JOURNAL OF MEDICINE
- Identification of potential inhibitors of three key enzymes of SARS-CoV2 using computational approach
- (2020) Hafsa Iftikhar et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening
- (2020) Xiaoxuan Zhao et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19
- (2020) Ling Li et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach
- (2020) Syed Ovais Aftab et al. Journal of Translational Medicine
- Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
- (2020) Abdo A. Elfiky LIFE SCIENCES
- Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease
- (2020) Mahmoud Kandeel et al. LIFE SCIENCES
- Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)
- (2020) Li Runfeng et al. PHARMACOLOGICAL RESEARCH
- Review: An insight into coronaviruses: Challenges, security and scope
- (2020) Niyati Shah et al. REVIEWS IN MEDICAL VIROLOGY
- Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
- (2020) Sepideh Sadegh et al. Nature Communications
- Viroinformatics approach to explore the inhibitory mechanism of existing drugs repurposed to fight against COVID-19
- (2020) Nousheen Bibi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Matrix metallopeptidase 9 as a host protein target of chloroquine and melatonin for immunoregulation in COVID-19: A network-based meta-analysis
- (2020) Suvojit Hazra et al. LIFE SCIENCES
- Role of ACE2 receptor and the landscape of treatment options from convalescent plasma therapy to the drug repurposing in COVID-19
- (2020) Pravindra Kumar et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19
- (2020) Wesley H. Self et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- From SARS to MERS, Thrusting Coronaviruses into the Spotlight
- (2019) Zhiqi Song et al. Viruses-Basel
- Inventing new therapies without reinventing the wheel: the power of drug repurposing
- (2018) Andreas Papapetropoulos et al. BRITISH JOURNAL OF PHARMACOLOGY
- Anakinra for the treatment of rheumatoid arthritis: a safety evaluation
- (2018) Julio Ramírez et al. Expert Opinion On Drug Safety
- FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell‐Induced Severe or Life‐Threatening Cytokine Release Syndrome
- (2018) Robert Q. Le et al. ONCOLOGIST
- Review of Drug Repositioning Approaches and Resources
- (2018) Hanqing Xue et al. International Journal of Biological Sciences
- Drug repurposing: progress, challenges and recommendations
- (2018) Sudeep Pushpakom et al. NATURE REVIEWS DRUG DISCOVERY
- Coronaviruses — drug discovery and therapeutic options
- (2016) Alimuddin Zumla et al. NATURE REVIEWS DRUG DISCOVERY
- In silico methods for drug repurposing and pharmacology
- (2016) Rachel A. Hodos et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus
- (2015) Kai-Wen Cheng et al. ANTIVIRAL RESEARCH
- Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease
- (2015) Jasper F. W. Chan et al. CLINICAL MICROBIOLOGY REVIEWS
- Protein localization vector propagation: a method for improving the accuracy of drug repositioning
- (2015) Yunku Yeu et al. Molecular BioSystems
- Potential Broad Spectrum Inhibitors of the Coronavirus 3CLpro: A Virtual Screening and Structure-Based Drug Design Study
- (2015) Michael Berry et al. Viruses-Basel
- The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis
- (2014) J. M. Lucas et al. Cancer Discovery
- A study protocol for a randomised open-label clinical trial of artesunate-mefloquine versus chloroquine in patients with non-severe Plasmodium knowlesi malaria in Sabah, Malaysia (ACT KNOW trial)
- (2014) M. J. Grigg et al. BMJ Open
- Middle East Respiratory Syndrome Coronavirus Infection Mediated by the Transmembrane Serine Protease TMPRSS2
- (2013) Kazuya Shirato et al. JOURNAL OF VIROLOGY
- Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry
- (2012) M. Kawase et al. JOURNAL OF VIROLOGY
- Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference
- (2012) Feixiong Cheng et al. PLoS Computational Biology
- Drug repositioning for orphan diseases
- (2011) D. Sardana et al. BRIEFINGS IN BIOINFORMATICS
- Arbidol: A Broad-Spectrum Antiviral Compound that Blocks Viral Fusion
- (2008) Y. Boriskin et al. CURRENT MEDICINAL CHEMISTRY
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum
- (2008) Kèvin Knoops et al. PLOS BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started