Cancer Vaccines: Promising Therapeutics or an Unattainable Dream

Cancer Vaccines: Adjuvant Potency, Importance of Age, Lifestyle, and Treatments

(2021) Stefania Cuzzubbo et al.   Frontiers in Immunology

Primary immunoprevention of adult onset cancers by vaccinating against retired tissue-specific self-proteins

(2020) Vincent K. Tuohy et al.   SEMINARS IN IMMUNOLOGY

Tumor-Associated Macrophages: Recent Insights and Therapies

(2020) Jiawei Zhou et al.   Frontiers in Oncology

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

(2020) João Calmeiro et al.   Pharmaceutics

Nanotherapeutic systems for delivering cancer vaccines: recent advances

(2020) Sarwar Beg et al.   Nanomedicine

Better Adjuvants for Better Vaccines: Progress in Adjuvant Delivery Systems, Modifications, and Adjuvant–Antigen Codelivery

(2020) Zhi-Biao Wang et al.   Vaccines

A Phase 2 Study of Allogeneic GM-CSF Transfected Pancreatic Tumor Vaccine (GVAX) with Ipilimumab as Maintenance Treatment for Metastatic Pancreatic Cancer

(2020) Annie A. Wu et al.   CLINICAL CANCER RESEARCH

Efficacy and safety of the therapeutic cancer vaccine tecemotide (L-BLP25) in early breast cancer: Results from a prospective, randomised, neoadjuvant phase II study (ABCSG 34)

(2020) Christian F. Singer et al.   EUROPEAN JOURNAL OF CANCER

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

(2020) Ugur Sahin et al.   NATURE

The route of administration dictates the immunogenicity of peptide-based cancer vaccines in mice

(2019) Hussein Sultan et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Anti-tumoral Effects of Recombinant Lactococcus lactis Strain Secreting IL-17A Cytokine

(2019) Elsa Jacouton et al.   Frontiers in Microbiology

Exosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention

(2019) Kavitha Yaddanapudi et al.   OncoImmunology

Turning the corner on therapeutic cancer vaccines

(2019) Robert E. Hollingsworth et al.   npj Vaccines

Regulatory T cells in cancer immunosuppression — implications for anticancer therapy

(2019) Yosuke Togashi et al.   Nature Reviews Clinical Oncology

Phase III Trial of PROSTVAC in Asymptomatic or Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer

(2019) James L. Gulley et al.   JOURNAL OF CLINICAL ONCOLOGY

A phase I multicenter study to assess the safety, tolerability, and immunogenicity of mRNA-4157 alone in patients with resected solid tumors and in combination with pembrolizumab in patients with unresectable solid tumors.

(2019) Howard A. Burris et al.   JOURNAL OF CLINICAL ONCOLOGY

Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination

(2019) Linda Hammerich et al.   NATURE MEDICINE

The clinical application of cancer immunotherapy based on naturally circulating dendritic cells

(2019) Kalijn F. Bol et al.   Journal for ImmunoTherapy of Cancer

PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance

(2019) Vivek Verma et al.   NATURE IMMUNOLOGY

DNA sensing by the cGAS–STING pathway in health and disease

(2019) Mona Motwani et al.   NATURE REVIEWS GENETICS

Bioinspired and Biomimetic Nanotherapies for the Treatment of Infectious Diseases

(2019) Guoyu Yang et al.   Frontiers in Pharmacology

Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine

(2019) Mona O. Mohsen et al.   Frontiers in Immunology

Peptides as cancer vaccines

(2019) Marta Calvo Tardón et al.   CURRENT OPINION IN PHARMACOLOGY

Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?

(2019) Fengzhi Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Immunotherapy in Metastatic Castration-Resistant Prostate Cancer: Past and Future Strategies for Optimization

(2019) Melissa A. Reimers et al.   Current Urology Reports

Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine

(2019) Caterina Lapenta et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The first clinical use of a recombinant Lactococcus lactis expressing human papillomavirus type 16 E7 oncogene oral vaccine: A phase I safety and immunogenicity trial in healthy women volunteers

(2019) Amir Hossein Mohseni et al.   MOLECULAR CANCER THERAPEUTICS

Combined Vaccination with NY-ESO-1 Protein, Poly-ICLC, and Montanide Improves Humoral and Cellular Immune Responses in Patients with High-Risk Melanoma

(2019) Anna Pavlick et al.   Cancer Immunology Research

Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer

(2019) Harm Westdorp et al.   Journal for ImmunoTherapy of Cancer

Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo

(2018) Nigel G. Kooreman et al.   Cell Stem Cell

Current challenges for cancer vaccine adjuvant development

(2018) William S. Bowen et al.   Expert Review of Vaccines

MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial

(2018) Brigitte Dreno et al.   LANCET ONCOLOGY

Dendritic cells in cancer immunotherapy

(2018) Camille M. Le Gall et al.   NATURE MATERIALS

Talimogene laherparepvec: First in class oncolytic virotherapy

(2018) Robert M. Conry et al.   Human Vaccines & Immunotherapeutics

Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination

(2018) Tyler W. Hulett et al.   Journal for ImmunoTherapy of Cancer

Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica

(2018) Marco Antonio Hernández-Luna et al.   Journal of Immunology Research

Trial watch: peptide-based vaccines in anticancer therapy

(2018) Lucillia Bezu et al.   OncoImmunology

Nanomedicine: Principles, Properties, and Regulatory Issues

(2018) Sara Soares et al.   Frontiers in Chemistry

Emerging Role and Future Directions of Immunotherapy in Advanced Ovarian Cancer

(2018) Thinle Chodon et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Actively personalized vaccination trial for newly diagnosed glioblastoma

(2018) Norbert Hilf et al.   NATURE

High Therapeutic Efficacy of a New Survivin LSP-Cancer Vaccine Containing CD4+ and CD8+ T-Cell Epitopes

(2018) Fanny Onodi et al.   Frontiers in Oncology

Recent progress in GM-CSF-based cancer immunotherapy

(2017) Wan-Lun Yan et al.   Immunotherapy

Revised Overall Survival Analysis of a Phase II, Randomized, Double-Blind, Controlled Study of PROSTVAC in Men With Metastatic Castration-Resistant Prostate Cancer

(2017) Philip W. Kantoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Results from a phase 2b, randomized, multicenter study of GVAX pancreas and CRS-207 compared to chemotherapy in adults with previously-treated metastatic pancreatic adenocarcinoma (ECLIPSE Study).

(2017) Dung T. Le et al.   JOURNAL OF CLINICAL ONCOLOGY

NY-ESO-1 Protein Cancer Vaccine With Poly-ICLC and OK-432

(2017) Tomohira Takeoka et al.   JOURNAL OF IMMUNOTHERAPY

Myeloid-derived suppressor cells—a new therapeutic target to overcome resistance to cancer immunotherapy

(2017) Jason A. Chesney et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

(2017) Yuanzeng Min et al.   Nature Nanotechnology

Tumor Mutational Burden and Response Rate to PD-1 Inhibition

(2017) Mark Yarchoan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Progress in prophylactic human papillomavirus (HPV) vaccination in 2016: A literature review

(2017) Polona J. Maver et al.   VACCINE

Prospective assessment of a gene signature potentially predictive of clinical benefit in metastatic melanoma patients following MAGE-A3 immunotherapeutic (PREDICT)

(2016) P. Saiag et al.   ANNALS OF ONCOLOGY

Plasma membrane vesicles decorated with glycolipid-anchored antigens and adjuvants via protein transfer as an antigen delivery platform for inhibition of tumor growth

(2016) Jaina M. Patel et al.   BIOMATERIALS

Systematic review of the use of granulocyte–macrophage colony-stimulating factor in patients with advanced melanoma

(2016) Christoph Hoeller et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Clinical study of a survivin long peptide vaccine (SurVaxM) in patients with recurrent malignant glioma

(2016) Robert A. Fenstermaker et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Dendritic cell-based immunotherapy

(2016) Rachel L Sabado et al.   CELL RESEARCH

Talimogene Laherparepvec for the Treatment of Advanced Melanoma

(2016) P. A. Ott et al.   CLINICAL CANCER RESEARCH

Algenpantucel-L immunotherapy in pancreatic adenocarcinoma

(2016) Andrew L Coveler et al.   Immunotherapy

Vaccine adjuvants as potential cancer immunotherapeutics

(2016) Burcu Temizoz et al.   INTERNATIONAL IMMUNOLOGY

Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma

(2016) Sofie Wilgenhof et al.   JOURNAL OF CLINICAL ONCOLOGY

Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial

(2016) Johan F Vansteenkiste et al.   LANCET ONCOLOGY

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients

(2016) Alena Gros et al.   NATURE MEDICINE

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

(2016) N. McGranahan et al.   SCIENCE

Immunological Mechanisms Underneath the Efficacy of Cancer Therapy

(2016) L. Galluzzi et al.   Cancer Immunology Research

Vaccination of stage III/IV melanoma patients with long NY-ESO-1 peptide and CpG-B elicits robust CD8+ and CD4+ T-cell responses with multiple specificities including a novel DR7-restricted epitope

(2016) P. Baumgaertner et al.   OncoImmunology

Targeted Vaccination against Human α-Lactalbumin for Immunotherapy and Primary Immunoprevention of Triple Negative Breast Cancer

(2016) Vincent Tuohy et al.   Cancers

WT1 vaccination in AML and MDS: A pilot trial with synthetic analog peptides

(2015) Jason Brayer et al.   AMERICAN JOURNAL OF HEMATOLOGY

Tecemotide in unresectable stage III non-small-cell lung cancer in the phase III START study: updated overall survival and biomarker analyses

(2015) P. Mitchell et al.   ANNALS OF ONCOLOGY

Sipuleucel-T (Provenge®)—Autopsy of an Innovative Paradigm Change in Cancer Treatment: Why a Single-Product Biotech Company Failed to Capitalize on its Breakthrough Invention

(2015) Szymon Jarosławski et al.   BIODRUGS

A randomized pilot trial testing the safety and immunologic effects of a MAGE-A3 protein plus AS15 immunostimulant administered into muscle or into dermal/subcutaneous sites

(2015) Craig L. Slingluff et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells

(2015) G. Schreibelt et al.   CLINICAL CANCER RESEARCH

Prophylactic HPV vaccination: past, present, and future

(2015) P. E. CASTLE et al.   EPIDEMIOLOGY AND INFECTION

A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer

(2015) G. Giaccone et al.   EUROPEAN JOURNAL OF CANCER

Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer

(2015) Dung T. Le et al.   JOURNAL OF CLINICAL ONCOLOGY

A Phase I Clinical Trial of CD1c (BDCA-1)+ Dendritic Cells Pulsed With HLA-A*0201 Peptides for Immunotherapy of Metastatic Hormone Refractory Prostate Cancer

(2015) Rebecca L. Prue et al.   JOURNAL OF IMMUNOTHERAPY

Safety and immunologic correlates of Melanoma GVAX, a GM-CSF secreting allogeneic melanoma cell vaccine administered in the adjuvant setting

(2015) Evan J Lipson et al.   Journal of Translational Medicine

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

(2015) Sebastian Kreiter et al.   NATURE

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

Immunogenicity of somatic mutations in human gastrointestinal cancers

(2015) E. Tran et al.   SCIENCE

A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells

(2015) B. M. Carreno et al.   SCIENCE

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

(2015) Juan Fu et al.   Science Translational Medicine

Safety and tolerability evaluation of the use of Montanide ISA™51 as vaccine adjuvant: A systematic review

(2015) Eva van Doorn et al.   Human Vaccines & Immunotherapeutics

Dendritic cell targeted vaccines: Recent progresses and challenges

(2015) Pengfei Chen et al.   Human Vaccines & Immunotherapeutics

Cancer Immunotherapy and Breaking Immune Tolerance: New Approaches to an Old Challenge

(2014) A. Makkouk et al.   CANCER RESEARCH

Safety, Correlative Markers, and Clinical Results of Adjuvant Nivolumab in Combination with Vaccine in Resected High-Risk Metastatic Melanoma

(2014) G. T. Gibney et al.   CLINICAL CANCER RESEARCH

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

(2014) Fei Duan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

(2014) Matthew M. Gubin et al.   NATURE

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

The mechanism of action of BCG therapy for bladder cancer—a current perspective

(2014) Gil Redelman-Sidi et al.   Nature Reviews Urology

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tecemotide: An antigen-specific cancer immunotherapy

(2014) Gregory T Wurz et al.   Human Vaccines & Immunotherapeutics

The long-term immune response after HPV16 peptide vaccination in women with low-grade pre-malignant disorders of the uterine cervix: a placebo-controlled phase II study

(2013) Peggy J. de Vos van Steenwijk et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

(2013) J. Tel et al.   CANCER RESEARCH

Selection of Immunostimulant AS15 for Active Immunization With MAGE-A3 Protein: Results of a Randomized Phase II Study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma

(2013) Wim H.J. Kruit et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor Exome Analysis Reveals Neoantigen-Specific T-Cell Reactivity in an Ipilimumab-Responsive Melanoma

(2013) Nienke van Rooij et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety, Efficacy, and Biomarkers of Nivolumab With Vaccine in Ipilimumab-Refractory or -Naive Melanoma

(2013) Jeffrey S. Weber et al.   JOURNAL OF CLINICAL ONCOLOGY

Adjuvant MAGE-A3 Immunotherapy in Resected Non–Small-Cell Lung Cancer: Phase II Randomized Study Results

(2013) Johan Vansteenkiste et al.   JOURNAL OF CLINICAL ONCOLOGY

Comparison of Vaccine-Induced Effector CD8 T Cell Responses Directed against Self- and Non-Self-Tumor Antigens: Implications for Cancer Immunotherapy

(2013) S. R. Pedersen et al.   JOURNAL OF IMMUNOLOGY

Evaluation of Ipilimumab in Combination With Allogeneic Pancreatic Tumor Cells Transfected With a GM-CSF Gene in Previously Treated Pancreatic Cancer

(2013) Dung T. Le et al.   JOURNAL OF IMMUNOTHERAPY

Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial

(2013) Charles Butts et al.   LANCET ONCOLOGY

Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas

(2013) I Sakamaki et al.   LEUKEMIA

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

(2013) Paul F Robbins et al.   NATURE MEDICINE

Mechanism of Immunopotentiation and Safety of Aluminum Adjuvants

(2013) Harm HogenEsch   Frontiers in Immunology

BiVax: a peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses

(2012) Hyun-Il Cho et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Addition of Algenpantucel-L Immunotherapy to Standard Adjuvant Therapy for Pancreatic Cancer: a Phase 2 Study

(2012) Jeffrey M. Hardacre et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

(2012) Ravi A Madan et al.   LANCET ONCOLOGY

Vaccination with Embryonic Stem Cells Protects against Lung Cancer: Is a Broad-Spectrum Prophylactic Vaccine against Cancer Possible?

(2012) Kavitha Yaddanapudi et al.   PLoS One

T-Cell Tolerance: Central and Peripheral

(2012) Y. Xing et al.   Cold Spring Harbor Perspectives in Biology

Sipuleucel-T (Provenge) autologous vaccine approved for treatment of men with asymptomatic or minimally symptomatic castrate-resistant metastatic prostate cancer

(2012) Thomas Gardner et al.   Human Vaccines & Immunotherapeutics

An intra-patient placebo-controlled phase I trial to evaluate the safety and tolerability of intradermal IMM-101 in melanoma

(2011) J. Stebbing et al.   ANNALS OF ONCOLOGY

A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma

(2011) Lutz Eric et al.   ANNALS OF SURGERY

Lung Cancer Vaccines

(2011) Ronan J. Kelly et al.   CANCER JOURNAL

Viral Vector-Based Therapeutic Cancer Vaccines

(2011) Cecilia Larocca et al.   CANCER JOURNAL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Administration of embryonic stem cells generates effective antitumor immunity in mice with minor and heavy tumor load

(2010) Wei Dong et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cellular Vaccine Approaches

(2010) Dung T. Le et al.   CANCER JOURNAL

Efficient In vivo Priming by Vaccination with Recombinant NY-ESO-1 Protein and CpG in Antigen Naive Prostate Cancer Patients

(2010) J. Karbach et al.   CLINICAL CANCER RESEARCH

Extended Dose Ipilimumab with a Peptide Vaccine: Immune Correlates Associated with Clinical Benefit in Patients with Resected High-Risk Stage IIIc/IV Melanoma

(2010) A. A. Sarnaik et al.   CLINICAL CANCER RESEARCH

Overall Survival Analysis of a Phase II Randomized Controlled Trial of a Poxviral-Based PSA-Targeted Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

(2010) John H. Sampson et al.   JOURNAL OF CLINICAL ONCOLOGY

Intradermal Vaccinations With RNA Coding for TAA Generate CD8+ and CD4+ Immune Responses and Induce Clinical Benefit in Vaccinated Patients

(2010) Susanne M Rittig et al.   MOLECULAR THERAPY

An autoimmune-mediated strategy for prophylactic breast cancer vaccination

(2010) Ritika Jaini et al.   NATURE MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Success or failure of vaccination for HPV16-positive vulvar lesions correlates with kinetics and phenotype of induced T-cell responses

(2010) M. J. P. Welters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase II trial of Belagenpumatucel-L, a TGF-β2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients

(2009) J Nemunaitis et al.   CANCER GENE THERAPY

Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells

(2009) Tim C.P. Somervaille et al.   Cell Stem Cell

Embryonic vaccines against cancer: An early history

(2009) Bradley G. Brewer et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Prostvac-VF: a vector-based vaccine targeting PSA in prostate cancer

(2009) Ravi A Madan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

Vaccination with Human Pluripotent Stem Cells Generates a Broad Spectrum of Immunological and Clinical Response against Colon Cancer

(2009) Yi Li et al.   STEM CELLS

Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors

(2008) S. Zhang et al.   CANCER RESEARCH

Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer

(2008) H. L. Kaufman et al.   CLINICAL CANCER RESEARCH

Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma

(2008) S.-H. Chiou et al.   CLINICAL CANCER RESEARCH

Allogeneic Granulocyte Macrophage Colony-Stimulating Factor-Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation

(2008) D. Laheru et al.   CLINICAL CANCER RESEARCH

Skin reactions to human papillomavirus (HPV) 16 specific antigens intradermally injected in healthy subjects and patients with cervical neoplasia

(2008) Muriel van den Hende et al.   INTERNATIONAL JOURNAL OF CANCER

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Oct-4 Expression Maintained Cancer Stem-Like Properties in Lung Cancer-Derived CD133-Positive Cells

(2008) Yu-Chih Chen et al.   PLoS One

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Galα1,3Galβ1,4GlcNAc-R (α-Gal) epitope: A carbohydrate of unique evolution and clinical relevance

(2007) Bruce A. Macher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS