Head-to-Head Comparison of Modular Vaccines Developed Using Different Capsid Virus-Like Particle Backbones and Antigen Conjugation Systems

Advantages and Prospects of Tag/Catcher Mediated Antigen Display on Capsid-Like Particle-Based Vaccines

(2020) Kara-Lee Aves et al.   Viruses-Basel

A Vaccine Displaying a Trimeric Influenza-A HA Stem Protein on Capsid-Like Particles Elicits Potent and Long-Lasting Protection in Mice

(2020) Susan Thrane et al.   Vaccines

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

(2019) Amelia Escolano et al.   NATURE

Spy&Go purification of SpyTag-proteins using pseudo-SpyCatcher to access an oligomerization toolbox

(2019) Irsyad N. A. Khairil Anuar et al.   Nature Communications

Role of Multivalency and Antigenic Threshold in Generating Protective Antibody Responses

(2019) Mark K. Slifka et al.   Frontiers in Immunology

Type of RNA Packed in VLPs Impacts IgG Class Switching—Implications for an Influenza Vaccine Design

(2019) Ariane C. Gomes et al.   Vaccines

Efficacy of the AS04-adjuvanted HPV-16/18 vaccine: Pooled analysis of the Costa Rica Vaccine and PATRICIA randomized controlled trials

(2019) Joseph E Tota et al.   JNCI-Journal of the National Cancer Institute

Approaching infinite affinity through engineering of peptide–protein interaction

(2019) Anthony H. Keeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SnoopLigase Catalyzes Peptide–Peptide Locking and Enables Solid-Phase Conjugate Isolation

(2018) Can M. Buldun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Explanations for the high potency of HPV prophylactic vaccines

(2018) John Schiller et al.   VACCINE

Evidence for single-dose protection by the bivalent HPV vaccine—Review of the Costa Rica HPV vaccine trial and future research studies

(2018) Aimée R. Kreimer et al.   VACCINE

New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue

(2018) Karl D. Brune et al.   Frontiers in Immunology

Virus-like particle display of HER2 induces potent anti-cancer responses

(2018) Arianna Palladini et al.   OncoImmunology

An Intrinsically Disordered Peptide-Peptide Stapler for Highly Efficient Protein Ligation Both in Vivo and in Vitro

(2018) Xia-Ling Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination

(2017) Mona O. Mohsen et al.   JOURNAL OF CONTROLLED RELEASE

Engineering Potato Virus X Particles for a Covalent Protein Based Attachment of Enzymes

(2017) Juliane Röder et al.   Small

Retargeting Lentiviruses via SpyCatcher-SpyTag Chemistry for Gene Delivery into Specific Cell Types

(2017) Nagarjun Kasaraneni et al.   mBio

Cell-permeable capsids as universal antigen carrier for the induction of an antigen-specific CD8+ T-cell response

(2017) Sami Akhras et al.   Scientific Reports

Probing the potential of CnaB-type domains for the design of tag/catcher systems

(2017) Marlene Pröschel et al.   PLoS One

Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin

(2017) J. Bonnet et al.   Scientific Reports

Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages

(2016) Mihails Shishovs et al.   JOURNAL OF MOLECULAR BIOLOGY

Programmable polyproteams built using twin peptide superglues

(2016) Gianluca Veggiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

(2016) Susan Thrane et al.   JOURNAL OF NANOBIOTECHNOLOGY

Kinetic Controlled Tag-Catcher Interactions for Directed Covalent Protein Assembly

(2016) Lee Ling Tan et al.   PLoS One

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

(2016) Karl D. Brune et al.   Scientific Reports

Efficacy of fewer than three doses of an HPV-16/18 AS04-adjuvanted vaccine: combined analysis of data from the Costa Rica Vaccine and PATRICIA trials

(2015) Aimée R Kreimer et al.   LANCET ONCOLOGY

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA

(2015) Susan Thrane et al.   PLoS One

IgG2 Antibodies against a Clinical Grade Plasmodium falciparum CSP Vaccine Antigen Associate with Protection against Transgenic Sporozoite Challenge in Mice

(2014) Robert Schwenk et al.   PLoS One

SpyLigase peptide–peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture

(2014) Jacob O. Fierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Analysis and Optimization of the Covalent Association between SpyCatcher and a Peptide Tag

(2013) Long Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate

(2013) Daniel DeMonte et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A universal virus-like particle-based vaccine for human papillomavirus: Longevity of protection and role of endogenous and exogenous adjuvants

(2013) Ebenezer Tumban et al.   VACCINE

Universal vaccine against influenza virus: Linking TLR signaling to anti-viral protection

(2012) Nicole Schmitz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate Immunity Mediates Follicular Transport of Particulate but Not Soluble Protein Antigen

(2012) A. Link et al.   JOURNAL OF IMMUNOLOGY

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superior Immunogenicity of Inactivated Whole Virus H5N1 Influenza Vaccine is Primarily Controlled by Toll-like Receptor Signalling

(2011) Felix Geeraedts et al.   PLoS Pathogens

Cutting Edge: Limited Specialization of Dendritic Cell Subsets for MHC Class II-Associated Presentation of Viral Particles

(2009) Susanne A. Keller et al.   JOURNAL OF IMMUNOLOGY

Analysis of Modified Human Papillomavirus Type 16 L1 Capsomeres: the Ability To Assemble into Larger Particles Correlates with Higher Immunogenicity

(2009) L. Schadlich et al.   JOURNAL OF VIROLOGY

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Direct Comparison of Human Papillomavirus Type 16 L1 Particles Reveals a Lower Immunogenicity of Capsomeres than Viruslike Particles with Respect to the Induced Antibody Response

(2008) N. Thones et al.   JOURNAL OF VIROLOGY