Advantages and Prospects of Tag/Catcher Mediated Antigen Display on Capsid-Like Particle-Based Vaccines

Factors That Govern the Induction of Long-Lived Antibody Responses

(2020) Bryce Chackerian et al.   Viruses-Basel

Immunological basis for enhanced immunity of nanoparticle vaccines

(2019) Hannah G Kelly et al.   Expert Review of Vaccines

Induction and decay of functional complement-fixing antibodies by the RTS,S malaria vaccine in children, and a negative impact of malaria exposure

(2019) Liriye Kurtovic et al.   BMC Medicine

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

(2019) Amelia Escolano et al.   NATURE

Spy&Go purification of SpyTag-proteins using pseudo-SpyCatcher to access an oligomerization toolbox

(2019) Irsyad N. A. Khairil Anuar et al.   Nature Communications

Production and characterization of novel ssRNA bacteriophage virus-like particles from metagenomic sequencing data

(2019) Ilva Liekniņa et al.   JOURNAL OF NANOBIOTECHNOLOGY

Type of RNA Packed in VLPs Impacts IgG Class Switching—Implications for an Influenza Vaccine Design

(2019) Ariane C. Gomes et al.   Vaccines

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

(2019) Edward P. Rybicki   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Virus-like particle-display of the enterotoxigenic Escherichia coli heat-stable toxoid STh-A14T elicits neutralizing antibodies in mice

(2019) Morten L. Govasli et al.   VACCINE

Self-Antigens Displayed on Liposomal Nanoparticles above a Threshold of Epitope Density Elicit Class-Switched Autoreactive Antibodies Independent of T Cell Help

(2019) Zhilin Chen et al.   JOURNAL OF IMMUNOLOGY

Approaching infinite affinity through engineering of peptide–protein interaction

(2019) Anthony H. Keeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Universal Plug-and-Display Vaccine Carrier Based on HBsAg VLP to Maximize Effective Antibody Response

(2019) Arianna Marini et al.   Frontiers in Immunology

Engineering a Rugged Nanoscaffold to Enhance Plug-and-Display Vaccination

(2018) Theodora Ulli Jordanka Bruun et al.   ACS Nano

SnoopLigase Catalyzes Peptide–Peptide Locking and Enables Solid-Phase Conjugate Isolation

(2018) Can M. Buldun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neutralization effects of antibody elicited by chimeric HBV S antigen viral-like particles presenting HCV neutralization epitopes

(2018) Sanhua Wei et al.   VACCINE

Explanations for the high potency of HPV prophylactic vaccines

(2018) John Schiller et al.   VACCINE

New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue

(2018) Karl D. Brune et al.   Frontiers in Immunology

Virus-like particle display of HER2 induces potent anti-cancer responses

(2018) Arianna Palladini et al.   OncoImmunology

B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen

(2018) Sheng Hong et al.   IMMUNITY

An Intrinsically Disordered Peptide-Peptide Stapler for Highly Efficient Protein Ligation Both in Vivo and in Vitro

(2018) Xia-Ling Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes

(2018) Talar Tokatlian et al.   Scientific Reports

Strategies to induce broadly protective antibody responses to viral glycoproteins

(2017) F Krammer   Expert Review of Vaccines

Native-like Env trimers as a platform for HIV-1 vaccine design

(2017) Rogier W. Sanders et al.   IMMUNOLOGICAL REVIEWS

Dual-linker gold nanoparticles as adjuvanting carriers for multivalent display of recombinant influenza hemagglutinin trimers and flagellin improve the immunological responses in vivo and in vitro

(2017) Chao Wang et al.   International Journal of Nanomedicine

Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination

(2017) Mona O. Mohsen et al.   JOURNAL OF CONTROLLED RELEASE

Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles

(2017) Marika Doucet et al.   PLoS One

Major findings and recent advances in virus–like particle (VLP)-based vaccines

(2017) Mona O. Mohsen et al.   SEMINARS IN IMMUNOLOGY

The complexity and cost of vaccine manufacturing – An overview

(2017) Stanley Plotkin et al.   VACCINE

Nanoparticles decorated with viral antigens are more immunogenic at low surface density

(2017) Matthew G. Brewer et al.   VACCINE

Retargeting Lentiviruses via SpyCatcher-SpyTag Chemistry for Gene Delivery into Specific Cell Types

(2017) Nagarjun Kasaraneni et al.   mBio

Cell-permeable capsids as universal antigen carrier for the induction of an antigen-specific CD8+ T-cell response

(2017) Sami Akhras et al.   Scientific Reports

Functional ferritin nanoparticles for biomedical applications

(2017) Zhantong Wang et al.   Frontiers of Chemical Science and Engineering

Escherichia coli-derived virus-like particles in vaccine development

(2017) Xiaofen Huang et al.   npj Vaccines

Probing the potential of CnaB-type domains for the design of tag/catcher systems

(2017) Marlene Pröschel et al.   PLoS One

Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

(2017) Darren B. Leneghan et al.   Scientific Reports

The True Story and Advantages of RNA Phage Capsids as Nanotools

(2016) Paul Pumpens et al.   INTERVIROLOGY

Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages

(2016) Mihails Shishovs et al.   JOURNAL OF MOLECULAR BIOLOGY

Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

(2016) Christoph M. Janitzek et al.   MALARIA JOURNAL

Programmable polyproteams built using twin peptide superglues

(2016) Gianluca Veggiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

(2016) Sodiomon B. Sirima et al.   VACCINE

Vaccine impact: Benefits for human health

(2016) Mark Doherty et al.   VACCINE

Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles

(2016) Linling He et al.   Nature Communications

Engineering virus-like particles as vaccine platforms

(2016) Kathryn M Frietze et al.   Current Opinion in Virology

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

(2016) Susan Thrane et al.   JOURNAL OF NANOBIOTECHNOLOGY

Kinetic Controlled Tag-Catcher Interactions for Directed Covalent Protein Assembly

(2016) Lee Ling Tan et al.   PLoS One

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

(2016) Karl D. Brune et al.   Scientific Reports

Different applications of virus-like particles in biology and medicine: Vaccination and delivery systems

(2015) Zeinab Shirbaghaee et al.   BIOPOLYMERS

His-tagged norovirus-like particles: A versatile platform for cellular delivery and surface display

(2015) Tiia Koho et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA

(2015) Susan Thrane et al.   PLoS One

Assessing sequence plasticity of a virus-like nanoparticle by evolution toward a versatile scaffold for vaccines and drug delivery

(2015) Yuan Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preclinical and clinical development of a dengue recombinant subunit vaccine

(2015) Susan B. Manoff et al.   VACCINE

Vaccine-preventable diseases in humanitarian emergencies among refugee and internally-displaced populations

(2015) Eugene Lam et al.   Human Vaccines & Immunotherapeutics

Raising Expectations For Subunit Vaccine

(2014) John T. Schiller et al.   JOURNAL OF INFECTIOUS DISEASES

SpyLigase peptide–peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture

(2014) Jacob O. Fierer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunization with a consensus epitope from human papillomavirus L2 induces antibodies that are broadly neutralizing

(2014) Mitchell Tyler et al.   VACCINE

Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes

(2014) Gunther Spohn et al.   Molecular Therapy-Methods & Clinical Development

Boosting Immunity to Small Tumor-Associated Carbohydrates with Bacteriophage Qβ Capsids

(2013) Zhaojun Yin et al.   ACS Chemical Biology

Escherichia coli-based cell free production of flagellin and ordered flagellin display on virus-like particles

(2013) Yuan Lu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Structural Analysis and Optimization of the Covalent Association between SpyCatcher and a Peptide Tag

(2013) Long Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Controlling Macromolecular Topology with Genetically Encoded SpyTag–SpyCatcher Chemistry

(2013) Wen-Bin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Innate Immunity Mediates Follicular Transport of Particulate but Not Soluble Protein Antigen

(2012) A. Link et al.   JOURNAL OF IMMUNOLOGY

Construction and Characterization of Virus-Like Particles: A Review

(2012) Andris Zeltins   MOLECULAR BIOTECHNOLOGY

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

(2012) B. Zakeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Review of Clinical Trials of Human Papillomavirus Prophylactic Vaccines

(2012) John T. Schiller et al.   VACCINE

Plant-derived virus-like particles as vaccines

(2012) Qiang Chen et al.   Human Vaccines & Immunotherapeutics

Surface Functionalization of Virus-Like Particles by Direct Conjugation Using Azide−Alkyne Click Chemistry

(2011) Kedar G. Patel et al.   BIOCONJUGATE CHEMISTRY

Cell Targeting with Hybrid Qβ Virus-Like Particles Displaying Epidermal Growth Factor

(2011) Jonathan K. Pokorski et al.   CHEMBIOCHEM

Choosing an effective protein bioconjugation strategy

(2011) Nicholas Stephanopoulos et al.   Nature Chemical Biology

The development of vaccines: how the past led to the future

(2011) Stanley A. Plotkin et al.   NATURE REVIEWS MICROBIOLOGY

Relationship between the size of nanoparticles and their adjuvant activity: Data from a study with an improved experimental design

(2010) Xinran Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses

(2010) Moses O Oyewumi et al.   Expert Review of Vaccines

Versatile Virus-Like Particle Carrier for Epitope Based Vaccines

(2010) Alain C. Tissot et al.   PLoS One

Carrier induced epitopic suppression of antibody responses induced by virus-like particles is a dynamic phenomenon caused by carrier-specific antibodies

(2010) Andrea Jegerlehner et al.   VACCINE

Growing Applications of “Click Chemistry” for Bioconjugation in Contemporary Biomedical Research

(2009) Kido Nwe et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Long-term persistence of anti-HPV-16 and -18 antibodies induced by vaccination with the AS04-adjuvanted cervical cancer vaccine: Modeling of sustained antibody responses☆

(2009) Marie-Pierre David et al.   GYNECOLOGIC ONCOLOGY

Cutting Edge: Limited Specialization of Dendritic Cell Subsets for MHC Class II-Associated Presentation of Viral Particles

(2009) Susanne A. Keller et al.   JOURNAL OF IMMUNOLOGY

Analysis of Modified Human Papillomavirus Type 16 L1 Capsomeres: the Ability To Assemble into Larger Particles Correlates with Higher Immunogenicity

(2009) L. Schadlich et al.   JOURNAL OF VIROLOGY

Insights into Long-Lasting Protection Induced by RTS,S/AS02A Malaria Vaccine: Further Results from a Phase IIb Trial in Mozambican Children

(2009) Caterina Guinovart et al.   PLoS One

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

(2008) Gunther Spohn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunogenic Display of Diverse Peptides on Virus-like Particles of RNA Phage MS2

(2008) David S. Peabody et al.   JOURNAL OF MOLECULAR BIOLOGY

A Direct Comparison of Human Papillomavirus Type 16 L1 Particles Reveals a Lower Immunogenicity of Capsomeres than Viruslike Particles with Respect to the Induced Antibody Response

(2008) N. Thones et al.   JOURNAL OF VIROLOGY

Phase I Trial of an Alhydrogel Adjuvanted Hepatitis B Core Virus-Like Particle Containing Epitopes of Plasmodium falciparum Circumsporozoite Protein

(2008) Aric L. Gregson et al.   PLoS One

A Vaccine against Nicotine for Smoking Cessation: A Randomized Controlled Trial

(2008) Jacques Cornuz et al.   PLoS One

Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies

(2008) Marina De Filette et al.   VACCINE