Toxoplasma gondii Type-I ROP18 Targeting Human E3 Ligase TRIM21 for Immune Escape

Upregulated E3 ligase tripartite motif‐containing protein 21 in psoriatic epidermis ubiquitylates nuclear factor‐κB p65 subunit and promotes inflammation in keratinocytes

(2020) L. Yang et al.   BRITISH JOURNAL OF DERMATOLOGY

The E3 Ubiquitin Ligase TRIM21 Promotes HBV DNA Polymerase Degradation

(2020) Ting Mu et al.   Viruses-Basel

HDAC6 regulates antibody-dependent intracellular neutralization of viruses via deacetylation of TRIM21

(2020) Songbo Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vacuolar escape of foodborne bacterial pathogens

(2020) Frans Bianchi et al.   JOURNAL OF CELL SCIENCE

TRIM21 Is Targeted for Chaperone-Mediated Autophagy during Salmonella Typhimurium Infection

(2020) Nina Judith Hos et al.   JOURNAL OF IMMUNOLOGY

Substrate recognition by TRIM and TRIM-like proteins in innate immunity

(2020) Hai-Tao Wang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

TRIM Proteins and Their Roles in the Influenza Virus Life Cycle

(2020) Hye-Ra Lee et al.   Microorganisms

The antiviral activities of TRIM proteins

(2020) Lennart Koepke et al.   CURRENT OPINION IN MICROBIOLOGY

Autophagy and innate immunity: Insights from invertebrate model organisms

(2018) Cheng-Ju Kuo et al.   Autophagy

Evasion of Human Neutrophil-Mediated Host Defense during Toxoplasma gondii Infection

(2018) Tatiane S. Lima et al.   mBio

Autophagy and Ubiquitination in Salmonella Infection and the Related Inflammatory Responses

(2018) Lidan Wang et al.   Frontiers in Cellular and Infection Microbiology

TRIM21 Restricts Coxsackievirus B3 Replication, Cardiac and Pancreatic Injury via Interacting With MAVS and Positively Regulating IRF3-Mediated Type-I Interferon Production

(2018) Hui Liu et al.   Frontiers in Immunology

Host Cell Vimentin Restrains Toxoplasma gondii Invasion and Phosphorylation of Vimentin is Partially Regulated by Interaction with TgROP18

(2017) Cheng He et al.   International Journal of Biological Sciences

NLRP3 and Potassium Efflux Drive Rapid IL-1β Release from Primary Human Monocytes duringToxoplasma gondiiInfection

(2017) Lanny Gov et al.   JOURNAL OF IMMUNOLOGY

A Human Proteome Array Approach to Identifying Key Host Proteins Targeted byToxoplasmaKinase ROP18

(2017) Zhaoshou Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

Trim13 Potentiates Toll-Like Receptor 2–Mediated Nuclear Factor κ B Activation via K29-Linked Polyubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6

(2017) Bin Huang et al.   MOLECULAR PHARMACOLOGY

TRIM21 and the Function of Antibodies inside Cells

(2017) David A. Rhodes et al.   TRENDS IN IMMUNOLOGY

Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA

(2017) Evgenij Fiskin et al.   Nature Communications

TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles

(2017) Clémence Foltz et al.   Scientific Reports

Role of vertical transmission ofToxoplasma gondiiin prevalence of infection

(2016) Geoff Hide   Expert Review of Anti-Infective Therapy

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

(2016) Ji-An Pan et al.   MOLECULAR CELL

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells

(2016) Barbara Clough et al.   PLoS Pathogens

Ubiquitin in the activation and attenuation of innate antiviral immunity

(2015) Steven M. Heaton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toxoplasma gondiidissemination: a parasite's journey through the infected host

(2015) K. S. Harker et al.   PARASITE IMMUNOLOGY

Diversity of bacterial manipulation of the host ubiquitin pathways

(2014) Yan Zhou et al.   CELLULAR MICROBIOLOGY

Natural killer cell intrinsic toll-like receptor MyD88 signaling contributes to IL-12-dependent IFN-γ production by mice during infection with Toxoplasma gondii

(2014) Yiyue Ge et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Toxoplasma gondiiVirulence Factor ROP18 Inhibits the Host NF-κB Pathway by Promoting p65 Degradation

(2014) Jian Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIpartite Motif 21 (TRIM21) Differentially Regulates the Stability of Interferon Regulatory Factor 5 (IRF5) Isoforms

(2014) Elisa Lazzari et al.   PLoS One

TRIM38 inhibits TNF - and IL-1 -triggered NF- B activation by mediating lysosome-dependent degradation of TAB2/3

(2014) M.-M. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The global burden of congenital toxoplasmosis: a systematic review

(2013) Paul R Torgerson et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

The role of ‘eat-me’ signals and autophagy cargo receptors in innate immunity

(2013) Keith B. Boyle et al.   CURRENT OPINION IN MICROBIOLOGY

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

Intracellular antibody receptor TRIM21 prevents fatal viral infection

(2013) M. Vaysburd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Innate Immunity to Toxoplasma gondii Is Mediated by Host Caspase-1 and ASC and Parasite GRA15

(2013) L. Gov et al.   mBio

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium

(2012) Alan Huett et al.   Cell Host & Microbe

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response

(2012) Takahito Sanada et al.   NATURE

Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins

(2011) Taro Kawai et al.   EMBO Molecular Medicine

Tripartite motif 8 (TRIM8) modulates TNF - and IL-1 -triggered NF- B activation by targeting TAK1 for K63-linked polyubiquitination

(2011) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains

(2010) Shengkai Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxoplasma gondii: epidemiology, feline clinical aspects, and prevention

(2010) Stacey A. Elmore et al.   TRENDS IN PARASITOLOGY

Latest update on the Ro/SS-A autoantibody system

(2009) J. Schulte-Pelkum et al.   AUTOIMMUNITY REVIEWS

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response

(2009) Hiroshi Ashida et al.   NATURE CELL BIOLOGY

Kiss and spit: the dual roles of Toxoplasma rhoptries

(2007) John C. Boothroyd et al.   NATURE REVIEWS MICROBIOLOGY