Autophagy and innate immunity: Insights from invertebrate model organisms

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

(2017) Shai Bel et al.   SCIENCE

HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans

(2016) Huan-Da Chen et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Local and long-range activation of innate immunity by infection and damage in C. elegans

(2016) Jonathan J. Ewbank et al.   CURRENT OPINION IN IMMUNOLOGY

C. elegansmidbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagy

(2016) Gholamreza Fazeli et al.   JOURNAL OF CELL SCIENCE

Avoidance and Subversion of Eukaryotic Homeostatic Autophagy Mechanisms by Bacterial Pathogens

(2016) Cheryl Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

Digesting the Expanding Mechanisms of Autophagy

(2016) Nicholas T. Ktistakis et al.   TRENDS IN CELL BIOLOGY

An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense

(2016) Mehran Najibi et al.   Cell Reports

A Large Collection of Novel Nematode-Infecting Microsporidia and Their Diverse Interactions with Caenorhabditis elegans and Other Related Nematodes

(2016) Gaotian Zhang et al.   PLoS Pathogens

Endosymbiosis and Eukaryotic Cell Evolution

(2015) John M. Archibald   CURRENT BIOLOGY

Microbial pathogenesis and host defense in the nematode C. elegans

(2015) Lianne B Cohen et al.   CURRENT OPINION IN MICROBIOLOGY

Emerging themes in bacterial autophagy

(2015) Matthew T Sorbara et al.   CURRENT OPINION IN MICROBIOLOGY

Mitophagy confers resistance to siderophore-mediated killing byPseudomonas aeruginosa

(2015) Natalia V. Kirienko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self and Nonself: How Autophagy Targets Mitochondria and Bacteria

(2014) Felix Randow et al.   Cell Host & Microbe

Intestinal autophagy activity is essential for host defense against Salmonella typhimurium infection in Caenorhabditis elegans

(2014) Alexander Curt et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Master manipulators: an update on Legionella pneumophila Icm/Dot translocated substrates and their host targets

(2014) Dervla T Isaac et al.   Future Microbiology

Antiviral Autophagy Restricts Rift Valley Fever Virus Infection and Is Conserved from Flies to Mammals

(2014) Ryan H. Moy et al.   IMMUNITY

Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes

(2014) Orane Visvikis et al.   IMMUNITY

Autophagy protects C. elegans against necrosis during Pseudomonas aeruginosa infection

(2014) C.-G. Zou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitin-Mediated Response to Microsporidia and Virus Infection in C. elegans

(2014) Malina A. Bakowski et al.   PLoS Pathogens

Bacteria and the Aging and Longevity of Caenorhabditis elegans

(2013) Dennis H. Kim   Annual Review of Genetics

Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria

(2013) Jamaal L. Benjamin et al.   Cell Host & Microbe

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death

(2013) Natalia V. Kirienko et al.   Cell Host & Microbe

Antimicrobial Autophagy: A Conserved Innate Immune Response inDrosophila

(2013) Ryan H. Moy et al.   Journal of Innate Immunity

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

Virus Recognition by Toll-7 Activates Antiviral Autophagy in Drosophila

(2012) Margaret Nakamoto et al.   IMMUNITY

Autophagy regulates Wolbachia populations across diverse symbiotic associations

(2012) D. Voronin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Ce-Duox1/BLI-3 Generated Reactive Oxygen Species Trigger Protective SKN-1 Activity via p38 MAPK Signaling during Infection in C. elegans

(2011) Ransome van der Hoeven et al.   PLoS Pathogens

Phosphorylation of the Conserved Transcription Factor ATF-7 by PMK-1 p38 MAPK Regulates Innate Immunity in Caenorhabditis elegans

(2010) Robert P. Shivers et al.   PLoS Genetics

Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System

(2009) Russell E. Vance et al.   Cell Host & Microbe

Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus

(2009) Spencer Shelly et al.   IMMUNITY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

(2009) K. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections

(2008) Ken J. Ishii et al.   Cell Host & Microbe

Conditional inhibition of autophagy genes in adult Drosophila impairs immunity without compromising longevity

(2008) Chunli Ren et al.   EXPERIMENTAL GERONTOLOGY

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY

Microsporidia Are Natural Intracellular Parasites of the Nematode Caenorhabditis elegans

(2008) Emily R Troemel et al.   PLOS BIOLOGY