Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins

The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-  Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3

(2014) R. Higgs et al.   JOURNAL OF IMMUNOLOGY

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Nucleic Acid Recognition by the Innate Immune System

(2011) Roman Barbalat et al.   Annual Review of Immunology

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

(2011) Glen N Barber   CURRENT OPINION IN IMMUNOLOGY

PIASy Inhibits Virus-induced and Interferon-stimulated Transcription through Distinct Mechanisms

(2011) Toru Kubota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Promyelocytic Leukemia Protein in Host Antiviral Defense

(2011) Marie-Claude Geoffroy et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

TRIM56 Is a Virus- and Interferon-Inducible E3 Ubiquitin Ligase That Restricts Pestivirus Infection

(2011) J. Wang et al.   JOURNAL OF VIROLOGY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

ISG15 and immune diseases

(2010) Young Joo Jeon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity

(2010) Wenwen Zeng et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Expanding role of ubiquitination in NF-κB signaling

(2010) Siqi Liu et al.   CELL RESEARCH

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA

(2010) Tetsuo Tsuchida et al.   IMMUNITY

Fas-associated Death Domain (FADD) and the E3 Ubiquitin-Protein Ligase TRIM21 Interact to Negatively Regulate Virus-induced Interferon Production

(2010) Jennifer A. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

(2010) Kazuhito Gotoh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I

(2010) Penghua Wang et al.   NATURE IMMUNOLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors

(2010) Rowan Higgs et al.   PLoS One

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

(2010) D. L. Mallery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

(2010) K.-i. Arimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

(2010) T. Satoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition

(2010) Semih U. Tareen et al.   VIROLOGY

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

(2009) Michaela Ulrike Gack et al.   Cell Host & Microbe

Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain

(2009) Bo Gao et al.   HEPATOLOGY

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

Ro52-mediated Monoubiquitination of IKK  Down-regulates NF- B Signalling

(2009) K. Wada et al.   JOURNAL OF BIOCHEMISTRY

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

(2009) Alexander Espinosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus

(2009) P. Eldin et al.   JOURNAL OF GENERAL VIROLOGY

Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF- B-Dependent Cytokine Expression in Fibroblasts

(2009) R. Yoshimi et al.   JOURNAL OF IMMUNOLOGY

TRIM21 Is Essential to Sustain IFN Regulatory Factor 3 Activation during Antiviral Response

(2009) K. Yang et al.   JOURNAL OF IMMUNOLOGY

Identification of TRIM23 as a Cofactor Involved in the Regulation of NF- B by Human Cytomegalovirus

(2009) E. Poole et al.   JOURNAL OF VIROLOGY

Ubiquitylation in innate and adaptive immunity

(2009) Vijay G. Bhoj et al.   NATURE

Linear polyubiquitylation: the missing link in NF–κB signalling

(2009) Arthur L. Haas   NATURE CELL BIOLOGY

Human TRIM Gene Expression in Response to Interferons

(2009) Laetitia Carthagena et al.   PLoS One

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

(2009) T. Saitoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of viral nucleic acids in innate immunity

(2009) Mitsutoshi Yoneyama et al.   REVIEWS IN MEDICAL VIROLOGY

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF- B through its N-terminal fragment

(2008) J. J. Chae et al.   BLOOD

Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties

(2008) Marco Sardiello et al.   BMC EVOLUTIONARY BIOLOGY

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells

(2008) Ricardo Rajsbaum et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

RNA recognition and signal transduction by RIG-I-like receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNOLOGICAL REVIEWS

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

(2008) Ken J. Ishii et al.   NATURE

TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation

(2008) Mude Shi et al.   NATURE IMMUNOLOGY

TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle

(2008) Pradeep D. Uchil et al.   PLoS Pathogens

TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved

(2008) A. H. Keeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations that impair interaction properties of TRIM32 associated with limb-girdle muscular dystrophy 2H

(2007) Valentina Saccone et al.   HUMAN MUTATION

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY