Application of metabolomics in clinical and laboratory gastrointestinal oncology

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Separation of carbohydrate isomers and anomers on poly-N-(1H-tetrazole-5-yl)-methacrylamide-bonded stationary phase by hydrophilic interaction chromatography as well as determination of anomer interconversion energy barriers

(2020) Xiaoqing Fu et al.   JOURNAL OF CHROMATOGRAPHY A

Association of serum levels of deoxyribose 1‑phosphate and S‑lactoylglutathione with neoadjuvant chemotherapy sensitivity in patients with gastric cancer: A metabolomics study

(2020) Daguang Wang et al.   Oncology Letters

Clinical relevance of the relationship between changes in gut microbiota and bile acid metabolism in patients with intrahepatic cholangiocarcinoma

(2020) Elisa Herraez et al.   Hepatobiliary Surgery and Nutrition

Integrating the MasSpec Pen to the da Vinci Surgical System for in vivo Tissue Analysis during a Robotic Assisted Porcine Surgery

(2020) Michael F. Keating et al.   ANALYTICAL CHEMISTRY

The potential of liquid biopsies in gastrointestinal cancer

(2020) Chenxi Wu et al.   CLINICAL BIOCHEMISTRY

Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography–mass spectrometry

(2020) Fujian Zheng et al.   Nature Protocols

Analysis of bile acid profile in plasma to differentiate cholangiocarcinoma from benign biliary diseases and healthy controls

(2020) Xiaofen Zhang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy

(2019) Chunfeng Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Post-cancer diagnosis dietary inflammatory potential is associated with survival among women diagnosed with colorectal cancer in the Women’s Health Initiative

(2019) Jiali Zheng et al.   EUROPEAN JOURNAL OF NUTRITION

Studying metabolic flux adaptations in cancer through integrated experimental-computational approaches

(2019) Shoval Lagziel et al.   BMC BIOLOGY

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

(2019) Sunny H. Wong et al.   Nature Reviews Gastroenterology & Hepatology

Identification of novel biomarkers of hepatocellular carcinoma by a high definition mass spectrometry; UHPLC‐QTOF/MS and DESI‐MSI

(2019) Koshi Nagai et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Metabolomics of Small Intestine Neuroendocrine Tumors and Related Hepatic Metastases

(2019) Alessio Imperiale et al.   Metabolites

METLIN: A Technology Platform for Identifying Knowns and Unknowns

(2018) Carlos Guijas et al.   ANALYTICAL CHEMISTRY

Metabolomics and Isotope Tracing

(2018) Cholsoon Jang et al.   CELL

Quality Control of Serum and Plasma by Quantification of (4E,14Z)-Sphingadienine-C18-1-Phosphate Uncovers Common Preanalytical Errors During Handling of Whole Blood

(2018) Xinyu Liu et al.   CLINICAL CHEMISTRY

A Large-scale, multicenter serum metabolite biomarker identification study for the early detection of hepatocellular carcinoma

(2018) Ping Luo et al.   HEPATOLOGY

Prospective metabolomics study identifies potential novel blood metabolites associated with pancreatic cancer risk

(2018) Xiang Shu et al.   INTERNATIONAL JOURNAL OF CANCER

Challenges and emergent solutions for LC-MS/MS based untargeted metabolomics in diseases

(2018) Liang Cui et al.   MASS SPECTROMETRY REVIEWS

Metabolomics activity screening for identifying metabolites that modulate phenotype

(2018) Carlos Guijas et al.   NATURE BIOTECHNOLOGY

Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin

(2018) Dannielle DeWaal et al.   Nature Communications

Human Gut Microbiota and Gastrointestinal Cancer

(2018) Changting Meng et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Identification of serum biomarkers of chemoradiosensitivity in esophageal cancer via the targeted metabolomics approach

(2018) Seiji Fujigaki et al.   Biomarkers in Medicine

Spatially resolved metabolomics to discover tumor-associated metabolic alterations

(2018) Chenglong Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Newborn screening for lysosomal storage disorders by tandem mass spectrometry in North East Italy

(2017) Alberto B. Burlina et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

(2017) Wei Jia et al.   Nature Reviews Gastroenterology & Hepatology

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial Respiration in Human Colorectal and Breast Cancer Clinical Material Is Regulated Differently

(2017) Andre Koit et al.   Oxidative Medicine and Cellular Longevity

Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system

(2017) Jialing Zhang et al.   Science Translational Medicine

Meat and Seafood Consumption in Relation to Plasma Metabolic Profiles in a Chinese Population: A Combined Untargeted and Targeted Metabolomics Study

(2017) Yonghai Lu et al.   Nutrients

Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry

(2017) Shin Nishiumi et al.   Oncotarget

Tissue amino acid profile could be used to differentiate advanced adenoma from colorectal cancer

(2016) Peng Gao et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer

(2016) Kathrine Røe Redalen et al.   RADIOTHERAPY AND ONCOLOGY

A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife

(2016) James Alexander et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Controversies regarding and perspectives on clinical utility of biomarkers in hepatocellular carcinoma

(2016) Pei-Pei Song   WORLD JOURNAL OF GASTROENTEROLOGY

Metabolome analysis via comprehensive two-dimensional liquid chromatography: identification of modified nucleosides from RNA metabolism

(2015) Lucas Willmann et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

1H-NMR urinary metabolomic profiling for diagnosis of gastric cancer

(2015) Angela W Chan et al.   BRITISH JOURNAL OF CANCER

Metabolomics for laboratory diagnostics

(2015) Renata Bujak et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapping

(2015) Raf Van de Plas et al.   NATURE METHODS

Fat, fibre and cancer risk in African Americans and rural Africans

(2015) Stephen J. D. O’Keefe et al.   Nature Communications

Mass-spectrometry-based microbial metabolomics: recent developments and applications

(2014) Peng Gao et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Fecal metabolomics: assay performance and association with colorectal cancer

(2014) James J. Goedert et al.   CARCINOGENESIS

A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential

(2014) Y. Qiu et al.   CLINICAL CANCER RESEARCH

Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases

(2014) Alison N. Thorburn et al.   IMMUNITY

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

(2014) Jared R Mayers et al.   NATURE MEDICINE

Preanalytical Aspects and Sample Quality Assessment in Metabolomics Studies of Human Blood

(2013) P. Yin et al.   CLINICAL CHEMISTRY

Tumor markers in colorectal cancer, gastric cancer and gastrointestinal stromal cancers: European group on tumor markers 2014 guidelines update

(2013) M.J. Duffy et al.   INTERNATIONAL JOURNAL OF CANCER

Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry

(2013) J. Balog et al.   Science Translational Medicine

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

(2012) M. Jain et al.   SCIENCE

Metabolomic NMR Fingerprinting to Identify and Predict Survival of Patients with Metastatic Colorectal Cancer

(2011) I. Bertini et al.   CANCER RESEARCH

Pharmacometabonomic Profiling as a Predictor of Toxicity in Patients with Inoperable Colorectal Cancer Treated with Capecitabine

(2011) A. Backshall et al.   CLINICAL CANCER RESEARCH

Plasma MicroRNA Panel to Diagnose Hepatitis B Virus–Related Hepatocellular Carcinoma

(2011) Jian Zhou et al.   JOURNAL OF CLINICAL ONCOLOGY

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

Tumor markers in pancreatic cancer: a European Group on Tumor Markers (EGTM) status report

(2009) M. J. Duffy et al.   ANNALS OF ONCOLOGY

Metabolic Control Analysis: A Tool for Designing Strategies to Manipulate Metabolic Pathways

(2008) Rafael Moreno-Sánchez et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Evidence of different metabolic phenotypes in humans

(2008) M. Assfalg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA