Process Analytical Technology Tools for Monitoring Pharmaceutical Unit Operations: A Control Strategy for Continuous Process Verification
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Process Analytical Technology Tools for Monitoring Pharmaceutical Unit Operations: A Control Strategy for Continuous Process Verification
Authors
Keywords
-
Journal
Pharmaceutics
Volume 13, Issue 6, Pages 919
Publisher
MDPI AG
Online
2021-06-22
DOI
10.3390/pharmaceutics13060919
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design
- (2021) Ji Yeon Kim et al. Pharmaceutics
- Real-time release testing of dissolution based on surrogate models developed by machine learning algorithms using NIR spectra, compression force and particle size distribution as input data
- (2021) Dorián László Galata et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Spectrophotometry and pharmaceutical PAT/RTRT: Practical challenges and regulatory landscape from development to product lifecycle
- (2021) Michele Panzitta et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Continuous twin screw granulation: A complex interplay between formulation properties, process settings and screw design
- (2020) Christoph Portier et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Roller compaction: Infrared thermography as a PAT for monitoring powder flow from feeding to compaction zone
- (2020) Mingzhe Yu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In-line particle size measurement and process influences on rotary fluidized bed agglomeration
- (2020) Marcel Langner et al. POWDER TECHNOLOGY
- Analysis of granulation mechanism in a high-shear wet granulation method using near-infrared spectroscopy and stirring power consumption
- (2020) Keita Koyanagi et al. COLLOID AND POLYMER SCIENCE
- Real-time monitoring of multi-layered film coating processes using Raman spectroscopy
- (2020) Juliana Radtke et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Process Monitoring of Moisture Content and Mass Transfer Rate in a Fluidised Bed with a Low Cost Inline MEMS NIR Sensor
- (2020) Claudio R. Avila et al. PHARMACEUTICAL RESEARCH
- Advanced process design and understanding of continuous twin-screw granulation via implementation of in-line process analytical technologies
- (2019) Wei Meng et al. ADVANCED POWDER TECHNOLOGY
- Optimisation of an in-line Raman spectroscopic method for continuous API quantification during twin-screw wet granulation and its application for process characterisation
- (2019) Julia Harting et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Using focused beam reflectance measurement (FBRM) to monitor aggregate structures formed in flocculated clay suspensions
- (2019) Y. Kyoda et al. MINERALS ENGINEERING
- Fluidised bed granulation of two APIs: QbD approach and development of a NIR in-line monitoring method
- (2019) Alexandru Gavan et al. Asian Journal of Pharmaceutical Sciences
- Comprehensive Study of Intermediate and Critical Quality Attributes for Process Control of High-Shear Wet Granulation Using Multivariate Analysis and the Quality by Design Approach
- (2019) Jong Kwon Han et al. Pharmaceutics
- Scale-Up Strategy in Quality by Design Approach for Pharmaceutical Blending Process with Discrete Element Method Simulation
- (2019) Su Bin Yeom et al. Pharmaceutics
- PAT-based batch statistical process control of a manufacturing process for a pharmaceutical ointment
- (2019) N. Bostijn et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Implementation of real-time and in-line feedback control for a fluid bed granulation process
- (2019) Theresa Reimers et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Near-Infrared Spectroscopy to Determine Residual Moisture in Freeze-Dried Products: Model Generation by Statistical Design of Experiments
- (2019) Matthieu Clavaud et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Continuous manufacturing process monitoring of pharmaceutical solid dosage form: A case study
- (2019) Yves Roggo et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Improved Understanding of the High Shear Wet Granulation Process under the Paradigm of Quality by Design Using Salvia miltiorrhiza Granules
- (2019) Yi Zhang et al. Pharmaceutics
- Application of chemometric methods to XRF-data – A tutorial review
- (2018) Vitaly Panchuk et al. ANALYTICA CHIMICA ACTA
- Potential of Near-Infrared Chemical Imaging as Process Analytical Technology Tool for Continuous Freeze-Drying
- (2018) Davinia Brouckaert et al. ANALYTICAL CHEMISTRY
- Method Development and Validation of an Inline Process Analytical Technology Method for Blend Monitoring in the Tablet Feed Frame Using Raman Spectroscopy
- (2018) Yi Li et al. ANALYTICAL CHEMISTRY
- Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer
- (2018) F. De Leersnyder et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Development of an in-line Raman spectroscopic method for continuous API quantification during twin-screw wet granulation
- (2018) Julia Harting et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Influence of extended dwell time during pre- and main compression on the properties of ibuprofen tablets
- (2018) E. Peeters et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Mass spectrometry in freeze-drying: Motivations for using a bespoke PAT for laboratory and production environment
- (2018) Arnab Ganguly et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Real time release testing of tablet content and content uniformity
- (2018) Daniel J. Goodwin et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Real-time process monitoring in a semi-continuous fluid-bed dryer – microwave resonance technology versus near-infrared spectroscopy
- (2018) Johanna Peters et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Optimization of a semi-batch tablet coating process for a continuous manufacturing line by design of experiments
- (2018) Shirin Barimani et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Monitoring of multiple solvent induced form changes during high shear wet granulation and drying processes using online Raman spectroscopy
- (2018) Jay Poorna Reddy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Development and validation of an in-line NIR spectroscopic method for continuous blend potency determination in the feed frame of a tablet press
- (2018) Fien De Leersnyder et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Coating process optimization through in-line monitoring for coating weight gain using Raman spectroscopy and design of experiments
- (2018) Byungsuk Kim et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Methodology for a Variable Rate Control Strategy Development in Continuous Manufacturing Applied to Twin-screw Wet-Granulation and Continuous Fluid-bed Drying
- (2018) Victoria Pauli et al. Journal of Pharmaceutical Innovation
- The Effect of Coating Composition and Geometry on TBC Lifetime
- (2018) Bruce A. Pint et al. JOURNAL OF ENGINEERING FOR GAS TURBINES AND POWER-TRANSACTIONS OF THE ASME
- Tablet Compression Force as a Process Analytical Technology (PAT): 100% Inspection and Control of Tablet Weight Uniformity
- (2018) Leo Manley et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Influence of spray nozzle aperture during high shear wet granulation on granule properties and its compression attributes
- (2018) Natalia Veronica et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Process analytical technology for continuous manufacturing tableting processing: A case study
- (2018) Victoria Pauli et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- A Review of the Applications of OCT for Analysing Pharmaceutical Film Coatings
- (2018) Hungyen Lin et al. Applied Sciences-Basel
- A DEM model-based study to quantitatively compare the effect of wet and dry binder addition in high-shear wet granulation processes
- (2018) Ashutosh Tamrakar et al. CHEMICAL ENGINEERING RESEARCH & DESIGN
- In-line monitoring of Ibuprofen during and after tablet compression using near-infrared spectroscopy
- (2018) Himmat Dalvi et al. TALANTA
- Impact of fill-level in twin-screw granulation on critical quality attributes of granules and tablets
- (2017) Robin Meier et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Evaluation of in–line Raman data for end-point determination of a coating process: Comparison of Science–Based Calibration, PLS-regression and univariate data analysis
- (2017) Shirin Barimani et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In-line Raman spectroscopic monitoring and feedback control of a continuous twin-screw pharmaceutical powder blending and tableting process
- (2017) Brigitta Nagy et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- RTD modeling of a continuous dry granulation process for process control and materials diversion
- (2017) Julia Kruisz et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Measurement of the Intertablet Coating Uniformity of a Pharmaceutical Pan Coating Process With Combined Terahertz and Optical Coherence Tomography In-Line Sensing
- (2017) Hungyen Lin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of solvent type on preparation of ethyl cellulose microparticles by solvent evaporation method with double emulsion system using focused beam reflectance measurement
- (2017) Muhaimin et al. POLYMER INTERNATIONAL
- Impact of roll compactor scale on ribbon density
- (2017) Ana Pérez Gago et al. POWDER TECHNOLOGY
- Using multiple Process Analytical Technology probes to monitor multivitamin blends in a tableting feed frame
- (2017) Pedro Durão et al. TALANTA
- Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach
- (2017) F. Shikata et al. RSC Advances
- A Systematic Approach of Employing Quality by Design Principles: Risk Assessment and Design of Experiments to Demonstrate Process Understanding and Identify the Critical Process Parameters for Coating of the Ethylcellulose Pseudolatex Dispersion Using Non-Conventional Fluid Bed Process
- (2016) Bhaveshkumar H. Kothari et al. AAPS PHARMSCITECH
- PAT-Based Control of Fluid Bed Coating Process Using NIR Spectroscopy to Monitor the Cellulose Coating on Pharmaceutical Pellets
- (2016) Venkata Ramana Naidu et al. AAPS PHARMSCITECH
- Topological modeling of methane hydrate crystallization from low to high water cut emulsion systems
- (2016) Aline Melchuna et al. FLUID PHASE EQUILIBRIA
- Evaluation of benchtop versus portable near-infrared spectroscopic method combined with multivariate approaches for the fast and simultaneous quantitative analysis of main sugars in syrup formulations
- (2016) Raphael Henn et al. FOOD CONTROL
- Development of a controlled release formulation by continuous twin screw granulation: Influence of process and formulation parameters
- (2016) V. Vanhoorne et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Principal component analysis: a review and recent developments
- (2016) Ian T. Jolliffe et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- Process optimization of dry granulation based tableting line: Extracting physical material characteristics from granules, ribbons and tablets using near-IR (NIR) spectroscopic measurement
- (2016) Milad Khorasani et al. POWDER TECHNOLOGY
- Quantitative analysis of topical gels and ointments by FT-Raman spectroscopy
- (2016) Sylwester Mazurek et al. VIBRATIONAL SPECTROSCOPY
- Development of an Ointment Formulation Using Hot-Melt Extrusion Technology
- (2015) Ajinkya M. Bhagurkar et al. AAPS PHARMSCITECH
- A study on the applicability of in-line measurements in the monitoring of the pellet coating process
- (2015) Grega Hudovornik et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Near-infrared chemical imaging (NIR-CI) as a process monitoring solution for a production line of roll compaction and tableting
- (2015) Milad Khorasani et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Visualization and prediction of porosity in roller compacted ribbons with near-infrared chemical imaging (NIR-CI)
- (2015) M. Khorasani et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Detailed analysis of the online near-infrared spectra of pharmaceutical blend in a rotary tablet press feed frame
- (2015) Slobodan Šašić et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- A Novel Microwave Sensor for Real-Time Online Monitoring of Roll Compacts of Pharmaceutical Powders Online—A Comparative Case Study with NIR
- (2015) Anshu Gupta et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- In-Line Monitoring of a Pharmaceutical Pan Coating Process by Optical Coherence Tomography
- (2015) Daniel Markl et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dependence of ejection force on tableting speed—A compaction simulation study
- (2015) Changquan Calvin Sun POWDER TECHNOLOGY
- Active content determination of pharmaceutical tablets using near infrared spectroscopy as Process Analytical Technology tool
- (2015) Pierre-François Chavez et al. TALANTA
- Study progression in application of process analytical technologies on film coating
- (2015) Tingting Peng et al. Asian Journal of Pharmaceutical Sciences
- Application of an Empirical FBRM Model to Estimate Crystal Size Distributions in Batch Crystallization
- (2014) Huayu Li et al. CRYSTAL GROWTH & DESIGN
- Development and Characterization of a Single Stage Mixed-Suspension, Mixed-Product-Removal Crystallization Process with a Novel Transfer Unit
- (2014) Guangyang Hou et al. CRYSTAL GROWTH & DESIGN
- The influence of API concentration on the roller compaction process: modeling and prediction of the post compacted ribbon, granule and tablet properties using multivariate data analysis
- (2014) Nathan Boersen et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Mixing and transport during pharmaceutical twin-screw wet granulation: Experimental analysis via chemical imaging
- (2014) Ashish Kumar et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models
- (2014) Margot Fonteyne et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In-line spatial filtering velocimetry for particle size and film thickness determination in fluidized-bed pellet coating processes
- (2014) Friederike Folttmann et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- PAT for tableting: Inline monitoring of API and excipients via NIR spectroscopy
- (2014) Patrick R. Wahl et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Development of Process Analytical Technology (PAT) methods for controlled release pellet coating
- (2014) P. Avalle et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- In-line monitoring of particle size in a fluid bed granulator: Investigations concerning positioning and configuration of the sensor
- (2014) Katrin Roßteuscher-Carl et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Verification of model development technique for NIR-based real-time monitoring of ingredient concentration during blending
- (2014) Hiroshi Nakagawa et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- NIR spectroscopy for the in-line monitoring of a multicomponent formulation during the entire freeze-drying process
- (2014) Juan G. Rosas et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Transfer from High‐Shear Batch to Continuous Twin Screw Wet Granulation: A Case Study in Understanding the Relationship Between Process Parameters and Product Quality Attributes
- (2014) Paul Beer et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A new approach to determine the homogeneity in hyperspectral imaging considering the particle size
- (2013) J.G. Rosas et al. ANALYTICA CHIMICA ACTA
- In-line monitoring of the drug content of powder mixtures and tablets by near-infrared spectroscopy during the continuous direct compression tableting process
- (2013) Kristiina Järvinen et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- A novel multivariate approach using science-based calibration for direct coating thickness determination in real-time NIR process monitoring
- (2013) C.-V. Möltgen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Fast freeze-drying cycle design and optimization using a PAT based on the measurement of product temperature
- (2013) Serena Bosca et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Use of near-infrared spectroscopy to quantify drug content on a continuous blending process: Influence of mass flow and rotation speed variations
- (2013) Lizbeth Martínez et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Visualization and understanding of the granulation liquid mixing and distribution during continuous twin screw granulation using NIR chemical imaging
- (2013) Jurgen Vercruysse et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Design Space Estimation of the Roller Compaction Process
- (2013) Nabil Souihi et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- PAT-tools for process control in pharmaceutical film coating applications
- (2013) Klaus Knop et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Optimization of the inter-tablet coating uniformity for an active coating process at lab and pilot scale
- (2013) Sarah Just et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Application of in-line near infrared spectroscopy and multivariate batch modeling for process monitoring in fluid bed granulation
- (2013) Ravikanth Kona et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Development and in-line validation of a Process Analytical Technology to facilitate the scale up of coating processes
- (2013) M. Wirges et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- The Use of Near-Infrared and Microwave Resonance Sensing to Monitor a Continuous Roller Compaction Process
- (2013) John Austin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Evaluation of Three Approaches for Real-Time Monitoring of Roller Compaction with Near-Infrared Spectroscopy
- (2012) David Acevedo et al. AAPS PHARMSCITECH
- Monitoring Blending of Pharmaceutical Powders with Multipoint NIR Spectroscopy
- (2012) Otto Scheibelhofer et al. AAPS PHARMSCITECH
- Direct analysis in real time mass spectrometry and multivariate data analysis: A novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation
- (2012) Shanshan Zeng et al. ANALYTICA CHIMICA ACTA
- The effect of process parameters on audible acoustic emissions from high-shear granulation
- (2012) Erin M. Hansuld et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- A quality by design study applied to an industrial pharmaceutical fluid bed granulation
- (2012) Vera Lourenço et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Continuous twin screw granulation: Influence of process variables on granule and tablet quality
- (2012) J. Vercruysse et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- An evaluation of process parameters to improve coating efficiency of an active tablet film-coating process
- (2012) Jennifer Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The use of total reflectance X-ray fluorescence (TXRF) for the determination of metals in the pharmaceutical industry
- (2012) Frederick J. Antosz et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Critical review of near-infrared spectroscopic methods validations in pharmaceutical applications
- (2012) C. De Bleye et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Twin screw wet granulation: Influence of formulation parameters on granule properties and growth behavior
- (2012) A.S. El Hagrasy et al. POWDER TECHNOLOGY
- Twin screw granulation using conveying screws: Effects of viscosity of granulation liquids and flow of powders
- (2012) Ranjit M. Dhenge et al. POWDER TECHNOLOGY
- Development of a fluid bed granulation process control strategy based on real-time process and product measurements
- (2012) Anneleen Burggraeve et al. TALANTA
- Monitoring of a pharmaceutical blending process using near infrared chemical imaging
- (2012) Zhisheng Wu et al. VIBRATIONAL SPECTROSCOPY
- Inline Real-Time Near-Infrared Granule Moisture Measurements of a Continuous Granulation–Drying–Milling Process
- (2011) Lipika Chablani et al. AAPS PHARMSCITECH
- Twin screw wet granulation: Effect of powder feed rate
- (2011) Ranjit M. Dhenge et al. ADVANCED POWDER TECHNOLOGY
- Comparison of near infrared and microwave resonance sensors for at-line moisture determination in powders and tablets
- (2011) Claudia C. Corredor et al. ANALYTICA CHIMICA ACTA
- Massing in high shear wet granulation can simultaneously improve powder flow and deteriorate powder compaction: A double-edged sword
- (2011) Limin Shi et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Development of a Process Analytical Technology (PAT) for in-line monitoring of film thickness and mass of coating materials during a pan coating operation
- (2011) Claire Gendre et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Batch statistical process control of a fluid bed granulation process using in-line spatial filter velocimetry and product temperature measurements
- (2011) A. Burggraeve et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Combining microwave resonance technology to multivariate data analysis as a novel PAT tool to improve process understanding in fluid bed granulation
- (2011) Vera Lourenço et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Spray granulation for drug formulation
- (2011) Zhi Hui Loh et al. Expert Opinion on Drug Delivery
- Multivariate data analysis applied to spectroscopy: Potential application to juice and fruit quality
- (2011) D. Cozzolino et al. FOOD RESEARCH INTERNATIONAL
- Combining formulation and process aspects for optimizing the high-shear wet granulation of common drugs
- (2011) Mauro Cavinato et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A priori performance prediction in pharmaceutical wet granulation: Testing the applicability of the nucleation regime map to a formulation with a broad size distribution and dry binder addition
- (2011) Defne Kayrak-Talay et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Real-time assessment of critical quality attributes of a continuous granulation process
- (2011) Margot Fonteyne et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Evaluation of the impact of mixing speed on the compressibility and compactibility of paracetamol-isomalt containing granules with factorial design
- (2011) Zs. Sáska et al. POWDER TECHNOLOGY
- Monitoring quality attributes for high-shear wet granulation with audible acoustic emissions
- (2011) Erin M. Hansuld et al. POWDER TECHNOLOGY
- NIR analysis of pharmaceutical samples without reference data: Improving the calibration
- (2011) M. Blanco et al. TALANTA
- Towards a robust water content determination of freeze-dried samples by near-infrared spectroscopy
- (2010) Holger Grohganz et al. ANALYTICA CHIMICA ACTA
- Twin screw wet granulation: Granule properties
- (2010) Ranjit M. Dhenge et al. CHEMICAL ENGINEERING JOURNAL
- Real-time monitoring of drug concentration in a continuous powder mixing process using NIR spectroscopy
- (2010) Aditya U. Vanarase et al. CHEMICAL ENGINEERING SCIENCE
- Feasibility of Raman spectroscopy as PAT tool in active coating
- (2010) Joshua Müller et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Digital imaging as a process analytical technology tool for fluid-bed pellet coating process
- (2010) Miha Možina et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- An integrated Quality by Design (QbD) approach towards design space definition of a blending unit operation by Discrete Element Method (DEM) simulation
- (2010) Siegfried Adam et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Evaluation of in-line spatial filter velocimetry as PAT monitoring tool for particle growth during fluid bed granulation
- (2010) A. Burggraeve et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- A new PAT/QbD approach for the determination of blend homogeneity: Combination of on-line NIRS analysis with PC Scores Distance Analysis (PC-SDA)
- (2010) T. Puchert et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Effect of force feeder on tablet strength during compression
- (2010) Ajit S. Narang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process
- (2010) Atul D. Karande et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In line NIR quantification of film thickness on pharmaceutical pellets during a fluid bed coating process
- (2010) Min-Jeong Lee et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In-line analysis of a fluid bed pellet coating process using a combination of near infrared and Raman spectroscopy
- (2010) Andrey Bogomolov et al. JOURNAL OF CHEMOMETRICS
- Acetaminophen determination in low-dose pharmaceutical syrup by NIR spectroscopy
- (2010) E. Ziémons et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Development, validation and transfer of a Near Infrared method to determine in-line the end point of a fluidised drying process for commercial production batches of an approved oral solid dose pharmaceutical product
- (2010) Antonio Peinado et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- A PAT Approach to Improve Process Understanding of High Shear Wet Granulation Through In-Line Particle Measurement Using FBRM C35
- (2010) Jun Huang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Modeling of Pan Coating Processes: Prediction of Tablet Content Uniformity and Determination of Critical Process Parameters
- (2010) Wei Chen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Process optimization for continuous extrusion wet granulation
- (2010) Li Tan et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Roller compaction: Application of an in-gap ribbon porosity calculation for the optimization of downstream granule flow and compactability characteristics
- (2010) John F. Gamble et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Effect of batch size on mechanical properties of granules in high shear granulation
- (2010) Chirangano Mangwandi et al. POWDER TECHNOLOGY
- Wet granulation in laboratory-scale high shear mixers: Effect of chopper presence, design and impeller speed
- (2010) T.M. Chitu et al. POWDER TECHNOLOGY
- Near-infrared spectroscopy quantitative determination of Pefloxacin mesylate concentration in pharmaceuticals by using partial least squares and principal component regression multivariate calibration
- (2010) Yunfei Xie et al. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
- Optimization of a pharmaceutical freeze-dried product and its process using an experimental design approach and innovative process analyzers
- (2010) T.R.M. De Beer et al. TALANTA
- Analysis of pharmaceuticals by NIR spectroscopy without a reference method
- (2010) Marcelo Blanco et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Modeling and Control of Roller Compaction for Pharmaceutical Manufacturing. Part I: Process Dynamics and Control Framework
- (2010) Shuo-Huan Hsu et al. Journal of Pharmaceutical Innovation
- Predicting Particle Size During Fluid Bed Granulation Using Process Measurement Data
- (2009) Tero Närvänen et al. AAPS PHARMSCITECH
- Chord length distributions measurements during crystallization and agglomeration of gas hydrate in a water-in-oil emulsion: Simulation and experimentation
- (2009) Hung Leba et al. CHEMICAL ENGINEERING SCIENCE
- Measurement and Calibration of Droplet Size Distributions in Water-in-Oil Emulsions by Particle Video Microscope and a Focused Beam Reflectance Method
- (2009) John A. Boxall et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Role of excipients in the quantification of water in lyophilised mixtures using NIR spectroscopy
- (2009) Holger Grohganz et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools
- (2009) T.R.M. De Beer et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Spray Drying Technique. I: Hardware and Process Parameters
- (2009) Krzysztof Cal et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dynamic Calibration for the In-Line NIR Monitoring of Film Thickness of Pharmaceutical Tablets Processed in a Fluid-Bed Coater
- (2009) Min-Jeong Lee et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Wet Granulation in a Twin‐Screw Extruder: Implications of Screw Design
- (2009) M.R. Thompson et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- On-line monitoring of a granulation process by NIR spectroscopy
- (2009) Manel Alcalà et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Measurement of fluidised bed dryer by different frequency and different normalisation methods with electrical capacitance tomography
- (2009) H.G. Wang et al. POWDER TECHNOLOGY
- Review of the most common pre-processing techniques for near-infrared spectra
- (2009) Åsmund Rinnan et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Feasibility and extension of universal quantitative models for moisture content determination in beta-lactam powder injections by near-infrared spectroscopy
- (2008) Xue-Bo Zhang et al. ANALYTICA CHIMICA ACTA
- Measuring the particle size of a known distribution using the focused beam reflectance measurement technique
- (2008) David Greaves et al. CHEMICAL ENGINEERING SCIENCE
- Effect of curing characterization on the corrosion performance of polyester and polyester/epoxy powder coatings
- (2008) R. Mafi et al. CORROSION SCIENCE
- A Novel Imaging Technique to Investigate the Influence of Atomization Air Pressure on Film–Tablet Interfacial Thickness
- (2008) Dmytro Barbash et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Near InfraRed Spectroscopy homogeneity evaluation of complex powder blends in a small-scale pharmaceutical preformulation process, a real-life application
- (2008) I. Storme-Paris et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Applications of terahertz pulsed imaging to sustained-release tablet film coating quality assessment and dissolution performance
- (2008) Louise Ho et al. JOURNAL OF CONTROLLED RELEASE
- Measuring the distribution of density and tabletting force in pharmaceutical tablets by chemical imaging
- (2008) Christopher D. Ellison et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Non-invasive quantitative assessment of the content of pharmaceutical capsules using transmission Raman spectroscopy
- (2008) Charlotte Eliasson et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Raman spectroscopy as a process analytical technology (PAT) tool for the in-line monitoring and understanding of a powder blending process
- (2008) T.R.M. De Beer et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Process characterization of powder blending by near-infrared spectroscopy: Blend end-points and beyond
- (2008) Zhenqi Shi et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Quality by Design, Part II: Application of NIR Spectroscopy to Monitor the Coating Process for a Pharmaceutical Sustained Release Product
- (2008) Simin Hassannejad Tabasi et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Quality by Design, Part I: Application of NIR Spectroscopy to Monitor Tablet Manufacturing Process
- (2008) Simin Hassannejad Tabasi et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Interpretation of Focused Beam Reflectance Measurement (FBRM) Data via Simulated Crystallization
- (2008) Zai Qun Yu et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Effect of operating conditions and physico–chemical properties on the wet granulation kinetics in high shear mixer
- (2008) M. Benali et al. POWDER TECHNOLOGY
- The effect of processing parameters on pharmaceutical tablet properties
- (2008) I.C. Sinka et al. POWDER TECHNOLOGY
- Monitoring of High-shear Granulation using Acoustic Emission: Predicting Granule Properties
- (2008) Michelle K. Papp et al. Journal of Pharmaceutical Innovation
- The role of nozzle diameter on the microstructure and abrasion wear resistance of plasma sprayed composite coatings
- (2008) M.F. Morks et al. Journal of Manufacturing Processes
- Real-time monitoring of powder mixing in a convective blender using non-invasive reflectance NIR spectrometry
- (2007) Luke J. Bellamy et al. ANALYST
- In-line monitoring of granule moisture in fluidized-bed dryers using microwave resonance technology
- (2007) Caroline Buschmüller et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Determination of moisture content of lyophilized allergen vaccines by NIR spectroscopy
- (2007) Yiwu Zheng et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Real-Time Assessment of Granule and Tablet Properties Using In-line Data From a High-shear Granulation Process
- (2007) Pirjo Luukkonen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started