Successful Patient-Derived Organoid Culture of Gynecologic Cancers for Disease Modeling and Drug Sensitivity Testing

Mutated p53 portends improvement in outcomes when bevacizumab is combined with chemotherapy in advanced/recurrent endometrial cancer: An NRG Oncology study

(2021) Kimberly K. Leslie et al.   GYNECOLOGIC ONCOLOGY

Engineering organoids

(2021) Moritz Hofer et al.   Nature Reviews Materials

Small-molecule drug repurposing to target DNA damage repair and response pathways

(2020) Jacqueline A. Brinkman et al.   SEMINARS IN CANCER BIOLOGY

Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma

(2020) Hui Chen et al.   GYNECOLOGIC ONCOLOGY

The forefront of ovarian cancer therapy: update on PARP inhibitors

(2020) M.R. Mirza et al.   ANNALS OF ONCOLOGY

Human organoids: model systems for human biology and medicine

(2020) Jihoon Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Patient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug Responses

(2020) Chris Jenske de Witte et al.   Cell Reports

Endometrial Cancer: When Upfront Surgery Is Not an Option

(2020) Amelia Barcellini et al.   ONCOLOGY

Current recommendations and recent progress in endometrial cancer

(2019) Rebecca A. Brooks et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Efficient use of patient-derived organoids as a preclinical model for gynecologic tumors

(2019) Yoshiaki Maru et al.   GYNECOLOGIC ONCOLOGY

Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia

(2019) Federico Gaiti et al.   NATURE

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

(2019) Oded Kopper et al.   NATURE MEDICINE

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation

(2019) Cheri A. Pasch et al.   CLINICAL CANCER RESEARCH

Final Overall Survival of a Randomized Trial of Bevacizumab for Primary Treatment of Ovarian Cancer

(2019) Krishnansu S. Tewari et al.   JOURNAL OF CLINICAL ONCOLOGY

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019

(2019) Samir Gupta et al.   Journal of the National Comprehensive Cancer Network

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening

(2019) Matteo Boretto et al.   NATURE CELL BIOLOGY

Patient-derived explants, xenografts and organoids: 3-dimensional patient-relevant pre-clinical models in endometrial cancer

(2019) Anna Collins et al.   GYNECOLOGIC ONCOLOGY

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

(2019) Salo N. Ooft et al.   Science Translational Medicine

Characterization of a TP53 Somatic Variant of Unknown Function From an Ovarian Cancer Patient Using Organoid Culture and Computational Modeling

(2019) JIANLING BI et al.   CLINICAL OBSTETRICS AND GYNECOLOGY

Changes in ovarian cancer survival during the 20 years before the era of targeted therapy

(2018) Jung-Yun Lee et al.   BMC CANCER

Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu

(2018) Amanda N. Fader et al.   JOURNAL OF CLINICAL ONCOLOGY

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

(2018) Willemien J. van Driel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Personalized Cancer Medicine: An Organoid Approach

(2018) Hamidreza Aboulkheyr Es et al.   TRENDS IN BIOTECHNOLOGY

Organoids for Drug Discovery and Personalized Medicine

(2018) Toshio Takahashi   Annual Review of Pharmacology and Toxicology

Prediction of DNA Repair Inhibitor Response in Short Term Patient-Derived Ovarian Cancer Organoids

(2018) Sarah J. Hill et al.   Cancer Discovery

The Use of Endometrial Cancer Patient–Derived Organoid Culture for Drug Sensitivity Testing Is Feasible

(2017) Eugenia Girda et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Emerging Therapeutics to Overcome Chemoresistance in Epithelial Ovarian Cancer: A Mini-Review

(2017) Robert Cornelison et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

(2017) Chantal Pauli et al.   Cancer Discovery

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

(2016) Masayuki Fujii et al.   Cell Stem Cell

Chemoresistance and targeted therapies in ovarian and endometrial cancers

(2016) Kevin Brasseur et al.   Oncotarget

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial

(2015) Amit M Oza et al.   LANCET ONCOLOGY

USA Endometrial Cancer Projections to 2030: should we be concerned?

(2014) M Aamir Sheikh et al.   Future Oncology