Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening

Functional expression of the mechanosensitive PIEZO1 channel in primary endometrial epithelial cells and endometrial organoids

(2019) Aurélie Hennes et al.   Scientific Reports

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

(2018) Norman Sachs et al.   CELL

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

(2018) Takashi Seino et al.   Cell Stem Cell

Functional Expression of TRP Ion Channels in Endometrial Stromal Cells of Endometriosis Patients

(2018) Eleonora Persoons et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clonal Expansion and Diversification of Cancer-Associated Mutations in Endometriosis and Normal Endometrium

(2018) Kazuaki Suda et al.   Cell Reports

Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition

(2018) Masayuki Fujii et al.   Cell Stem Cell

The Use of Endometrial Cancer Patient–Derived Organoid Culture for Drug Sensitivity Testing Is Feasible

(2017) Eugenia Girda et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium

(2017) Margherita Y. Turco et al.   NATURE CELL BIOLOGY

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

(2017) Laura Broutier et al.   NATURE MEDICINE

Cancer-Associated Mutations in Endometriosis without Cancer

(2017) Michael S. Anglesio et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD34+mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury

(2017) Igor Stzepourginski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer

(2017) Jarno Drost et al.   SCIENCE

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

(2017) Chantal Pauli et al.   Cancer Discovery

Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis

(2017) Bingbing Wu et al.   Stem Cell Reports

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies

(2015) Jeroen Depreeuw et al.   GYNECOLOGIC ONCOLOGY

Models of endometriosis and their utility in studying progression to ovarian clear cell carcinoma

(2015) Claire M King et al.   JOURNAL OF PATHOLOGY

Proliferative and signaling activities of insulin analogues in endometrial cancer cells

(2015) Daniel Aizen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

(2014) Dong Gao et al.   CELL

Classification of endometrial carcinoma: more than two types

(2014) Rajmohan Murali et al.   LANCET ONCOLOGY

Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks

(2014) Hui Zhao et al.   eLife

SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis

(2013) A.J. Valentijn et al.   HUMAN REPRODUCTION

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Endometriosis: pathogenesis and treatment

(2013) Paolo Vercellini et al.   Nature Reviews Endocrinology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Endometrial carcinoma: molecular alterations involved in tumor development and progression

(2012) A Yeramian et al.   ONCOGENE

Differential expression of MMP-2, MMP-9 and PCNA in endometriosis and endometrial carcinoma

(2011) Marion T. Weigel et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Reproductive tract function and dysfunction in women

(2011) Angshumoy Roy et al.   Nature Reviews Endocrinology

Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy

(2010) C. M. Contreras et al.   Disease Models & Mechanisms

Dindel: Accurate indel calls from short-read data

(2010) C. A. Albers et al.   GENOME RESEARCH

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

(2009) H. B. Salvesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Matrix Metalloproteinases in the Pathogenesis of Endometriosis

(2009) Miltiadis Pitsos et al.   Reproductive Sciences

β-catenin mediates glandular formation and dysregulation of β-catenin induces hyperplasia formation in the murine uterus

(2008) J-W Jeong et al.   ONCOGENE