Is Emodin with Anticancer Effects Completely Innocent? Two Sides of the Coin

Emodin regulates cell cycle of non-small lung cancer (NSCLC) cells through hyaluronan synthase 2 (HA2)-HA-CD44/receptor for hyaluronic acid-mediated motility (RHAMM) interaction-dependent signaling pathway

(2021) Mingzhu Li et al.   Cancer Cell International

Emodin enhances cisplatin sensitivity in non-small cell lung cancer through Pgp downregulation

(2021) Shuai Peng et al.   Oncology Letters

Emodin Inhibits the Proliferation of MCF-7 Human Breast Cancer Cells Through Activation of Aryl Hydrocarbon Receptor (AhR)

(2021) Ning Zhang et al.   Frontiers in Pharmacology

Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis

(2021) Yunsha Zhang et al.   Frontiers in Oncology

Modulation of the triggered apoptosis by nano emodin transfersome-mediated sonodynamic therapy on head and neck squamous cell carcinoma cell lines

(2021) Maryam Pourhajibagher et al.   Photodiagnosis and Photodynamic Therapy

Emodin Interferes With AKT1-Mediated DNA Damage and Decreases Resistance of Breast Cancer Cells to Doxorubicin

(2021) Bo Li et al.   Frontiers in Oncology

Preparation and Evaluation of Novel Emodin-loaded Stearic Acid-g-chitosan Oligosaccharide Nanomicelles

(2020) Xiaohong Jiang et al.   Nanoscale Research Letters

Design, synthesis, molecular docking, and biological evaluation of new emodin anthraquinone derivatives as potential antitumor substances

(2020) Yuying Li et al.   CHEMISTRY & BIODIVERSITY

Nanoparticle-Based Drug Delivery System: A Patient-Friendly Chemotherapy for Oncology

(2020) Lina Yan et al.   Dose-Response

The isolation of secondary metabolites from Rheum ribes L. and the synthesis of new semi-synthetic anthraquinones: Isolation, synthesis and biological activity

(2020) Ibrahim Halil Gecibesler et al.   FOOD CHEMISTRY

Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis

(2019) Zibo Li et al.   Journal of Translational Medicine

Emodin Induces Death in Human Cervical Cancer Cells Through Mitotic Catastrophe

(2019) WOJCIECH TRYBUS et al.   ANTICANCER RESEARCH

Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways

(2019) Ian T. Saunders et al.   Cancer Cell International

Emodin, a natural anthraquinone, suppresses liver cancer in vitro and in vivo by regulating VEGFR2 and miR-34a

(2019) Jianguo Bai et al.   INVESTIGATIONAL NEW DRUGS

Emodin enhances antitumor effect of paclitaxel on human non-small-cell lung cancer cells in vitro and in vivo

(2019) Shuifang Chen et al.   Drug Design Development and Therapy

Anticancer Effects of Emodin on HepG2 Cell: Evidence from Bioinformatic Analysis

(2019) Rui-sheng Zhou et al.   Biomed Research International

Novel Approach to the Treatment of Diabetes: Embryonic Stem Cell and Insulin-Loaded Liposomes and Nanocochleates

(2019) Çiğdem Yücel et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Combined treatment with emodin and a telomerase inhibitor induces significant telomere damage/dysfunction and cell death

(2019) Rui Liu et al.   Cell Death & Disease

Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells

(2019) Nian Yang et al.   Frontiers in Pharmacology

Emodin suppresses growth and invasion of colorectal cancer cells by inhibiting VEGFR2

(2019) Guoliang Dai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Combination of targeted daunorubicin liposomes and targeted emodin liposomes for treatment of invasive breast cancer

(2019) Min Fu et al.   JOURNAL OF DRUG TARGETING

Synthesis and anti‐inflammatory effects of novel emodin derivatives bearing azole moieties

(2019) Xiaokang Zhu et al.   ARCHIV DER PHARMAZIE

Blocking mutation independent p53 aggregation by emodin modulates autophagic cell death pathway in lung cancer

(2018) Ejazul Haque et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Apoptosis: A Target for Anticancer Therapy

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling

(2018) Yue-Xiao Xing et al.   JOURNAL OF PROTEOME RESEARCH

Emodin inhibits colon cancer cell invasion and migration by suppressing epithelialmesenchymal transition via the Wnt/β-catenin pathway

(2018) Juan Gu et al.   ONCOLOGY RESEARCH

Emodin Induces Apoptosis of Colon Cancer Cells via Induction of Autophagy in a ROS-Dependent Manner

(2018) Yuanyuan Wang et al.   ONCOLOGY RESEARCH

Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines

(2018) Thais Fernanda Moreira et al.   Oxidative Medicine and Cellular Longevity

NMR-based Metabolomic Techniques Identify the Toxicity of Emodin in HepG2 Cells

(2018) Chang Chen et al.   Scientific Reports

N-acetylaminogalactosyl-decorated biodegradable PLGA-TPGS copolymer nanoparticles containing emodin for the active targeting therapy of liver cancer

(2018) Hao Dong et al.   Artificial Cells Nanomedicine and Biotechnology

Drug Delivery System for Emodin Based on Mesoporous Silica SBA-15

(2018) Tamara Krajnović et al.   Nanomaterials

Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP

(2018) Cong Zu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CYP3A Activation and Glutathione Depletion Aggravate Emodin-Induced Liver Injury

(2018) Li-Long Jiang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Emodin inhibits pancreatic cancer EMT and invasion by up‑regulating microRNA‑1271

(2018) Nan Li et al.   Molecular Medicine Reports

Emodin induces apoptosis in human hepatocellular carcinoma HepaRG cells via the mitochondrial caspase‑dependent pathway

(2018) Xiaoxv Dong et al.   ONCOLOGY REPORTS

Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism

(2018) Young-Seon Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase

(2017) Steffi K. Koerner et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis

(2017) Kyung Ha Lee et al.   Molecular Medicine Reports

Emodin induces apoptosis of lung cancer cells through ER stress and the TRIB3/NF-κB pathway

(2017) Jin Su et al.   ONCOLOGY REPORTS

WITHDRAWN: Silencing of lncRNA-CCDC26 Restrains the Growth and Migration of Glioma Cells In Vitro and In Vivo Via Targeting miR-203

(2017) Shilei Wang et al.   ONCOLOGY RESEARCH

Emodin suppresses proliferation, migration and invasion in ovarian cancer cells by down regulating ILK in vitro and in vivo

(2017) Jingjing Lu et al.   OncoTargets and Therapy

Emodin and rhein decrease levels of hypoxia-inducible factor-1α in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells

(2017) Lijuan Hu et al.   Oncotarget

Efficient Synthesis of Anthraquinones from Diaryl Carboxylic Acids via Palladium(II)-Catalyzed and Visible Light-Mediated Transformations

(2016) Kiho Kim et al.   ADVANCED SYNTHESIS & CATALYSIS

Comparative analysis of the major constituents in three related polygonaceous medicinal plants using pressurized liquid extraction and HPLC-ESI/MS

(2016) Jiafu Feng et al.   Analytical Methods

Involvement of PI3K/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis

(2016) Yuting Cui et al.   FOOD AND CHEMICAL TOXICOLOGY

Research advances for the extraction, analysis and uses of anthraquinones: A review

(2016) Johanna Duval et al.   INDUSTRIAL CROPS AND PRODUCTS

Cremophor EL-based nanoemulsion enhances transcellular permeation of emodin through glucuronidation reduction in UGT1A1-overexpressing MDCKII cells

(2016) Tianpeng Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Efficacy of Emodin/Paclitaxel Versus Paclitaxel for the Treatment of Ovarian Cancer in vivo

(2016) Dong-Ung Lee et al.   International Journal of Pharmacology

Anthraquinones As Pharmacological Tools and Drugs

(2016) Enas M. Malik et al.   MEDICINAL RESEARCH REVIEWS

Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages

(2016) S. Iwanowycz et al.   MOLECULAR CANCER THERAPEUTICS

Emodin inhibits epithelial to mesenchymal transition in epithelial ovarian cancer cells by regulation of GSK-3β/β-catenin/ZEB1 signaling pathway

(2016) CHEN HU et al.   ONCOLOGY REPORTS

Emodin induces hepatocellular carcinoma cell apoptosis through MAPK and PI3K/AKT signaling pathways in vitro and in vivo

(2016) Wanfu Lin et al.   ONCOLOGY REPORTS

Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics

(2016) Xiaoxv Dong et al.   PHYTOTHERAPY RESEARCH

Inhibition of human anthracycline reductases by emodin — A possible remedy for anthracycline resistance

(2016) Jan Hintzpeter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Emodin inhibits migration and invasion of MHCC-97H human hepatocellular carcinoma cells

(2016) Wanfu Lin et al.   Experimental and Therapeutic Medicine

Emodin Inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer Cells via ILK/GSK-3β/Slug Signaling Pathway

(2016) Jingjing Lu et al.   Biomed Research International

Inhibitory effect of emodin on human hepatoma cell line SMMC-7721 and its mechanism

(2015) X Zhang et al.   African Health Sciences

Effects of Aloe-emodin and Emodin on Proliferation of the MKN45 Human Gastric Cancer Cell Line

(2015) Takeshi Chihara et al.   Asian Pacific Journal of Cancer Prevention

Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity

(2015) Feng Cao et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Inhibition of integrin-linked kinase expression by emodin through crosstalk of AMPKα and ERK1/2 signaling and reciprocal interplay of Sp1 and c-Jun

(2015) Qing Tang et al.   CELLULAR SIGNALLING

Naturally Occurring Anthraquinones: Chemistry and Therapeutic Potential in Autoimmune Diabetes

(2015) Shih-Chang Chien et al.   Evidence-based Complementary and Alternative Medicine

Anti-Inflammatory Effect of Emodin via Attenuation of NLRP3 Inflammasome Activation

(2015) Ji-Won Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pharmacokinetics and tissue distribution of emodin loaded nanoemulsion in rats

(2015) Yanbin Shi et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Emodin inhibits splenocyte proliferation and inflammation by modulating cytokine responses in a mouse model system

(2015) Rahul Sharma et al.   Journal of Immunotoxicology

Emodin inhibits the proliferation of PC3 prostate cancer cells in vitro via the Notch signaling pathway

(2015) GANG DENG et al.   Molecular Medicine Reports

A Promising Emodin-Loaded Poly (Lactic-Co-Glycolic Acid)-d-α-Tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles for Liver Cancer Therapy

(2015) Hongyan Liu et al.   PHARMACEUTICAL RESEARCH

Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties

(2015) Nagaraja Reddy Rama Reddy et al.   PLoS One

Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin

(2015) Sandra Radić Brkanac et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Emodin inhibits human sperm functions by reducing sperm [Ca2+]i and tyrosine phosphorylation

(2015) Tao Luo et al.   REPRODUCTIVE TOXICOLOGY

Synergistic cancer growth-inhibitory effect of emodin and low-dose cisplatin on gastric cancer cells In vitro

(2015) L Huang et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Anti-tumor effect of emodin on gynecological cancer cells

(2015) Yaoxian Wang et al.   CELLULAR ONCOLOGY

Development of phenylboronic acid-functionalized nanoparticles for emodin delivery

(2015) Bo Wang et al.   Journal of Materials Chemistry B

Curcumin and Emodin Down-Regulate TGF-β Signaling Pathway in Human Cervical Cancer Cells

(2015) Pooja Chandrakant Thacker et al.   PLoS One

Antitumor Effects and Mechanism of Novel Emodin Rhamnoside Derivatives against Human Cancer Cells In Vitro

(2015) Jie-yu Xing et al.   PLoS One

Emodin-Provoked Oxidative Stress Induces Apoptosis in Human Colon Cancer HCT116 Cells through a p53-Mitochondrial Apoptotic Pathway

(2014) Mei-Juan Xie et al.   Asian Pacific Journal of Cancer Prevention

Emodin Inhibits Breast Cancer Cell Proliferation through the ERα-MAPK/Akt-Cyclin D1/Bcl-2 Signaling Pathway

(2014) Jia-Qi Sui et al.   Asian Pacific Journal of Cancer Prevention

Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs

(2014) Xuemei Jia et al.   BREAST CANCER RESEARCH AND TREATMENT

Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620

(2014) Thacker Pooja et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Emodin attenuates systemic and liver inflammation in hyperlipidemic mice administrated with lipopolysaccharides

(2014) Xuemei Jia et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Preparation of Lung-Targeting, Emodin-Loaded Polylactic Acid Microspheres and Their Properties

(2014) Xiaohong Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanopharmaceutics: Phytochemical-Based Controlled or Sustained Drug-Delivery Systems for Cancer Treatment

(2014) Roubeena Jeetah et al.   Journal of Biomedical Nanotechnology

Preparation of a nano emodin transfersome and study on its anti-obesity mechanism in adipose tissue of diet-induced obese rats

(2014) Kun Lu et al.   Journal of Translational Medicine

Emodin inhibits LOVO colorectal cancer cell proliferation via the regulation of the Bcl-2/Bax ratio and cytochrome c

(2014) LIANG MA et al.   Experimental and Therapeutic Medicine

Emodin Augments Cisplatin Cytotoxicity in Platinum-Resistant Ovarian Cancer Cells via ROS-Dependent MRP1 Downregulation

(2014) Jun Ma et al.   Biomed Research International

The combined effect of survivin-targeted shRNA and emodin on the proliferation and invasion of ovarian cancer cells

(2013) Hui Xue et al.   ANTI-CANCER DRUGS

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

(2013) Aruljothi Subramaniam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway

(2013) Wang Yaoxian et al.   Cancer Cell International

Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors

(2013) Bilel Jelassi et al.   CARCINOGENESIS

The applications of Vitamin E TPGS in drug delivery

(2013) Yuanyuan Guo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERαInhibition

(2013) Pao-Hsuan Huang et al.   Evidence-based Complementary and Alternative Medicine

Emodin sensitizes the gemcitabine-resistant cell line Bxpc-3/Gem to gemcitabine via downregulation of NF-κB and its regulated targets

(2013) WEI ZHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Emodin affects ERCC1 expression in breast cancer cells

(2013) Jian-min Fu et al.   Journal of Translational Medicine

Potent P-glycoprotein inhibition of emodin derivative: synthesis and biological evaluation

(2013) Jianhong Wang et al.   MEDICINAL CHEMISTRY RESEARCH

The distinct mechanisms of the antitumor activity of emodin in different types of cancer (Review)

(2013) WEI-TIAN WEI et al.   ONCOLOGY REPORTS

Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes

(2013) Wing-Yan Li et al.   PHARMACEUTICAL BIOLOGY

Emodin inhibits ATP-induced IL-1β secretion, ROS production and phagocytosis attenuation in rat peritoneal macrophages via antagonizing P2X7receptor

(2013) Shuyan Zhu et al.   PHARMACEUTICAL BIOLOGY

Preparation of novel antiproliferative emodin derivatives and studies on their cell cycle arrest, caspase dependent apoptosis and DNA binding interaction

(2013) T. Narender et al.   PHYTOMEDICINE

Apoptosis and DNA intercalating activities of novel emodin derivatives

(2013) T. Narender et al.   RSC Advances

Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis

(2013) Wing-Yan Li et al.   INFLAMMOPHARMACOLOGY

Improving the controlled release of water-insoluble emodin from amino-functionalized mesoporous silica

(2012) Yunqiang Xu et al.   APPLIED SURFACE SCIENCE

Effects of Emodin Extracted from Chinese Herbs on Proliferation of Non-small Cell Lung Cancer and Underlying Mechanisms

(2012) Lin He et al.   Asian Pacific Journal of Cancer Prevention

Synthesis and biological activity evaluation of emodin quaternary ammonium salt derivatives as potential anticancer agents

(2012) Wenfeng Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors

(2012) Francis Giraud et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: Roles of apoptotic cell death and LS1034 tumor xenografts model

(2012) Yi-Shih Ma et al.   FOOD AND CHEMICAL TOXICOLOGY

Emodin inhibits invasion and migration of prostate and lung cancer cells by downregulating the expression of chemokine receptor CXCR4

(2012) Sooho Ok et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Emodin loaded solid lipid nanoparticles: Preparation, characterization and antitumor activity studies

(2012) Shengpeng Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions

(2012) Shashank Masaldan et al.   JOURNAL OF APPLIED TOXICOLOGY

Emodin Regulates Apoptotic Pathway in Human Liver Cancer Cells

(2012) Jian-Qing Yu et al.   PHYTOTHERAPY RESEARCH

Antitumor Activity of Emodin against Pancreatic Cancer Depends on Its Dual Role: Promotion of Apoptosis and Suppression of Angiogenesis

(2012) Sheng-Zhang Lin et al.   PLoS One

Emodin As an Effective Agent in Targeting Cancer Stem-Like Side Population Cells of Gallbladder Carcinoma

(2012) Xin-xing Li et al.   STEM CELLS AND DEVELOPMENT

Emodin induces embryonic toxicity in mouse blastocysts through apoptosis

(2012) Mei-Hui Chang et al.   TOXICOLOGY

Downregulation of phosphatase of regenerating liver-3 is involved in the inhibition of proliferation and apoptosis induced by emodin in the SGC-7901 human gastric carcinoma cell line

(2012) ZHEN-HUA SUN et al.   Experimental and Therapeutic Medicine

Emodin Induces Apoptotic Death in Murine Myelomonocytic Leukemia WEHI-3 CellsIn Vitroand Enhances Phagocytosis in Leukemia MiceIn Vivo

(2011) Yuan-Chang Chang et al.   Evidence-based Complementary and Alternative Medicine

Blockade of Her2/neuBinding to Hsp90 by Emodin Azide Methyl Anthraquinone Derivative Induces Proteasomal Degradation of Her2/neu

(2011) Yan-yan Yan et al.   MOLECULAR PHARMACEUTICS

Modulation of Rad51, ERCC1, and thymidine phosphorylase by emodin result in synergistic cytotoxic effect in combination with capecitabine

(2010) Jen-Chung Ko et al.   BIOCHEMICAL PHARMACOLOGY

Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: The mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1

(2010) Xin-zhi Huang et al.   CANCER BIOLOGY & THERAPY

Chemosensitization by emodin, a plant-derived anti-cancer agent: mechanism of action

(2010) Yi Sun   CANCER BIOLOGY & THERAPY

Targeting apoptosis pathways in cancer by Chinese medicine

(2010) Min Li-Weber   CANCER LETTERS

Emodin inhibits the growth of hepatoma cells: Finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells

(2009) Chin-Mu Hsu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation

(2009) Wei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Suppression of ERCC1 and Rad51 expression through ERK1/2 inactivation is essential in emodin-mediated cytotoxicity in human non-small cell lung cancer cells

(2009) Jen-Chung Ko et al.   BIOCHEMICAL PHARMACOLOGY

Protein kinase inhibitors emodin and dichloro-ribofuranosylbenzimidazole modulate the cellular accumulation and cytotoxicity of cisplatin in a schedule-dependent manner

(2009) Tetsuji Kurokawa et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells

(2009) Jin-Mei Lai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo

(2009) Wang Chun-Guang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation

(2009) Ruey-Shyang Chen et al.   EXPERIMENTAL CELL RESEARCH

Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2

(2009) Jen-Chung Ko et al.   LUNG CANCER

Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non-Small-Cell Lung Cancer Cells

(2009) Y.-J. Su et al.   MOLECULAR PHARMACOLOGY

Emodin sensitizes paclitaxel-resistant human ovarian cancer cells to paclitaxel-induced apoptosis in vitro

(2009) Liu   ONCOLOGY REPORTS

Effects of emodin on the gene expression profiling of human breast carcinoma cells

(2009) Zhiwei Huang et al.   Cancer Detection and Prevention

Emodin-induced apoptosis in human breast cancer BCap-37 cells through the mitochondrial signaling pathway

(2008) Zhiwei Huang et al.   ARCHIVES OF PHARMACAL RESEARCH

Emodin induces apoptosis in human prostate cancer cell LNCaP

(2008) Chun-Xiao Yu et al.   ASIAN JOURNAL OF ANDROLOGY