Inhibition of Nicotinamide Phosphoribosyltransferase

NAD depletion by FK866 induces autophagy

(2014) Richard A. Billington et al.   Autophagy

Nicotinamide Phosphoribosyl Transferase/Pre-B Cell Colony-Enhancing Factor/Visfatin Is Required for Lymphocyte Development and Cellular Resistance to Genotoxic Stress

(2014) A. Rongvaux et al.   JOURNAL OF IMMUNOLOGY

NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death

(2010) C. C. Alano et al.   JOURNAL OF NEUROSCIENCE

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies

(2009) A. Nahimana et al.   BLOOD

The Nicotinamide Phosphoribosyltransferase: A Molecular Link between Metabolism, Inflammation, and Cancer

(2009) M. Galli et al.   CANCER RESEARCH

The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance

(2009) Shin-ichiro Imai   CELL BIOCHEMISTRY AND BIOPHYSICS

Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation

(2009) Christian Dölle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Poly(ADP-ribose) Catabolism Triggers AMP-dependent Mitochondrial Energy Failure

(2009) Laura Formentini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Localization of PARP-1 Requires Interaction with Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity

(2009) Marianna N. Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of Rattus norvegicus Visfatin/PBEF/Nampt in complex with an FK866-based inhibitor

(2009) Gil Bu Kang et al.   MOLECULES AND CELLS

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

(2009) Peter C. Fong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

(2009) Santina Bruzzone et al.   PLoS One

Emerging Roles of NAD+ and Its Metabolites in Cell Signaling

(2009) F. Koch-Nolte et al.   Science Signaling

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS