Boosting NAD+ with a small molecule that activates NAMPT

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

(2018) Luis Rajman et al.   Cell Metabolism

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

Nicotinamide N -Methyltransferase: More Than a Vitamin B3 Clearance Enzyme

(2017) Pavlos Pissios   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation

(2015) Stephen Rush Fuhs et al.   CELL

Physiological and pathophysiological roles of NAMPT and NAD metabolism

(2015) Antje Garten et al.   Nature Reviews Endocrinology

P7C3 Neuroprotective Chemicals Function by Activating the Rate-Limiting Enzyme in NAD Salvage

(2014) Gelin Wang et al.   CELL

Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase

(2014) Angela Oh et al.   CHEMBIOCHEM

NAD+ and sirtuins in aging and disease

(2014) Shin-ichiro Imai et al.   TRENDS IN CELL BIOLOGY

Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

(2013) Xiaozhang Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recycling Nicotinamide. The Transition-State Structure of Human Nicotinamide Phosphoribosyltransferase

(2013) Emmanuel S. Burgos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase

(2011) Ruo-Yu Zhang et al.   ANALYTICAL BIOCHEMISTRY

Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells

(2011) Andrey Nikiforov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clickable NAD Analogues for Labeling Substrate Proteins of Poly(ADP-ribose) Polymerases

(2010) Hong Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

(2009) M. Watson et al.   MOLECULAR AND CELLULAR BIOLOGY

A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT

(2009) E. S. Burgos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

Weak Coupling of ATP Hydrolysis to the Chemical Equilibrium of Human Nicotinamide Phosphoribosyltransferase†

(2008) Emmanuel S. Burgos et al.   BIOCHEMISTRY