Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes

Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spec‐trometry (GCIB‐SIMS)

(2021) Louis Sparvero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion

(2021) Ana-Marija Vučković et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer

(2020) Daiha Shin et al.   Redox Biology

α-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload

(2019) Giuseppina Camiolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Guidelines for evaluating myocardial cell death

(2019) Paras K Mishra et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease

(2019) Dominic P. Del Re et al.   PHYSIOLOGICAL REVIEWS

The Role of Adenine Nucleotide Translocase in the Assembly of Respiratory Supercomplexes in Cardiac Cells

(2019) Rebecca M. Parodi-Rullán et al.   Cells

Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells

(2018) Victoria I. Bunik et al.   BIOLOGICAL CHEMISTRY

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation

(2018) Michael M. Gaschler et al.   Nature Chemical Biology

REDOX-DRIVEN SIGNALING: 2-OXO ACID DEHYDROGENASE COMPLEXES AS SENSORS AND TRANSMITTERS OF METABOLIC IMBALANCE 

(2018) Victoria Bunik   ANTIOXIDANTS & REDOX SIGNALING

Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxia

(2018) Julian Hlouschek et al.   CANCER LETTERS

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Elucidating the contribution of ETC complexes I and II to the respirasome formation in cardiac mitochondria

(2018) Sehwan Jang et al.   Scientific Reports

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

(2016) Tanja Krainz et al.   ACS Central Science

The mitochondrial dicarboxylate and 2-oxoglutarate carriers do not transport glutathione

(2015) Lee M. Booty et al.   FEBS LETTERS

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

(2014) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats

(2014) Nelson Escobales et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Glutathione and mitochondria

(2014) Vicent Ribas et al.   Frontiers in Pharmacology

Mitochondrial Glutathione Transport Is a Key Determinant of Neuronal Susceptibility to Oxidative and Nitrosative Stress

(2013) Heather M. Wilkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The mitochondrial transporter family SLC25: Identification, properties and physiopathology

(2012) Ferdinando Palmieri   MOLECULAR ASPECTS OF MEDICINE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Diabetes and Alpha Lipoic Acid

(2011) Saeid Golbidi et al.   Frontiers in Pharmacology

α-Ketoglutarate dehydrogenase: A mitochondrial redox sensor

(2010) Aaron L. McLain et al.   FREE RADICAL RESEARCH

Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

(2010) Jerome Garcia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Control of Liver Function in Health and Disease

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme

(2009) Stefano Toppo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid

(2009) Attila Ambrus et al.   JOURNAL OF NEUROCHEMISTRY

Reversible Inhibition of α-Ketoglutarate Dehydrogenase by Hydrogen Peroxide:  Glutathionylation and Protection of Lipoic Acid†

(2007) Milana A. B. Applegate et al.   BIOCHEMISTRY