Mitochondrial Glutathione Transport Is a Key Determinant of Neuronal Susceptibility to Oxidative and Nitrosative Stress

Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione

(2011) Heather M. Wilkins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1G93A mice model

(2011) Marcelo R. Vargas et al.   NEUROBIOLOGY OF DISEASE

Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria

(2010) Christelle K. Kamga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells

(2010) P. Huypens et al.   DIABETOLOGIA

ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2

(2010) Steve Pedrini et al.   HUMAN MOLECULAR GENETICS

Mitochondrial glutathione uptake: characterization in isolated brain mitochondria and astrocytes in culture

(2009) Alison L. Wadey et al.   JOURNAL OF NEUROCHEMISTRY

Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance

(2009) Charles R Arthur et al.   Molecular Neurodegeneration

Levels of reduced and oxidized coenzymeQ-10 and 8-hydroxy-2′-deoxyguanosine in the cerebrospinal fluid of patients with living Parkinson's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process

(2009) Chiaki Isobe et al.   NEUROSCIENCE LETTERS

Increased mitochondrial oxidative damage and oxidative DNA damage contributes to the neurodegenerative process in sporadic amyotrophic lateral sclerosis

(2008) Takahiko Murata et al.   FREE RADICAL RESEARCH

Oxidant–antioxidant imbalance in the erythrocytes of sporadic amyotrophic lateral sclerosis patients correlates with the progression of disease

(2008) G. Nagesh Babu et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology