The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota

Gut microbiota generation of protein-bound uremic toxins and related metabolites is not altered at different stages of chronic kidney disease.

(2020) Tessa Gryp et al.   KIDNEY INTERNATIONAL

Composition of Gut Microbiota in Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

(2020) Lucía Iglesias-Vázquez et al.   Nutrients

Developmental Signatures of Microbiota-Derived Metabolites in the Mouse Brain

(2020) Jonathan R. Swann et al.   Metabolites

P-cresol Alters Brain Dopamine Metabolism and Exacerbates Autism-Like Behaviors in the BTBR Mouse

(2020) Tiziana Pascucci et al.   Brain Sciences

A metabolomics approach to investigate urine levels of neurotransmitters and related metabolites in autistic children

(2020) Federica Gevi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder

(2020) Brittany D. Needham et al.   BIOLOGICAL PSYCHIATRY

The maternal microbiome modulates fetal neurodevelopment in mice

(2020) Helen E. Vuong et al.   NATURE

Gut microbial molecules in behavioural and neurodegenerative conditions

(2020) Brittany D. Needham et al.   NATURE REVIEWS NEUROSCIENCE

The gut microbiota metabolite indole increases emotional responses and adrenal medulla activity in chronically stressed male mice

(2020) Hayatte-Dounia Mir et al.   PSYCHONEUROENDOCRINOLOGY

Ultrafast and accurate 16S rRNA microbial community analysis using Kraken 2

(2020) Jennifer Lu et al.   Microbiome

Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter

(2019) Tiphaine Le Roy et al.   Frontiers in Microbiology

A Novel Sparse Compositional Technique Reveals Microbial Perturbations

(2019) Cameron Martino et al.   mSystems

Altered composition and function of intestinal microbiota in autism spectrum disorders: a systematic review

(2019) Feitong Liu et al.   Translational Psychiatry

Gut Microbe to Brain Signaling: What Happens in Vagus…

(2019) Christine Fülling et al.   NEURON

Development of the LC-MS/MS method for determining the p-cresol level in plasma

(2019) Natalia Korytowska et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Do your gut microbes affect your brain dopamine?

(2019) Camila González-Arancibia et al.   PSYCHOPHARMACOLOGY

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

(2019) Gil Sharon et al.   CELL

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Long-term benefit of Microbiota Transfer Therapy on autism symptoms and gut microbiota

(2019) Dae-Wook Kang et al.   Scientific Reports

Association Between Gut Microbiota and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

(2019) Mingyu Xu et al.   Frontiers in Psychiatry

Δ9-Tetrahydrocannabinol During Adolescence Attenuates Disruption of Dopamine Function Induced in Rats by Maternal Immune Activation

(2019) Salvatore Lecca et al.   Frontiers in Behavioral Neuroscience

Impact of quality trimming on the efficiency of reads joining and diversity analysis of Illumina paired-end reads in the context of QIIME1 and QIIME2 microbiome analysis frameworks

(2019) Attayeb Mohsen et al.   BMC BIOINFORMATICS

Fmr1-Deficiency Impacts Body Composition, Skeleton, and Bone Microstructure in a Mouse Model of Fragile X Syndrome

(2019) Antoine Leboucher et al.   Frontiers in Endocrinology

Differences in fecal microbial metabolites and microbiota of children with autism spectrum disorders

(2018) Dae-Wook Kang et al.   ANAEROBE

Deficits in mesolimbic reward pathway underlie social interaction impairments in children with autism

(2018) Kaustubh Supekar et al.   BRAIN

Immune regulation by microbiome metabolites

(2018) Chang H. Kim   IMMUNOLOGY

Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats

(2018) Mathilde Jaglin et al.   Frontiers in Neuroscience

BLAST-based validation of metagenomic sequence assignments

(2018) Adam L. Bazinet et al.   PeerJ

Role of VTA dopamine neurons and neuroligin 3 in sociability traits related to nonfamiliar conspecific interaction

(2018) Sebastiano Bariselli et al.   Nature Communications

Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria

(2018) Ian J. Passmore et al.   PLoS Pathogens

Back-translating behavioral intervention for autism spectrum disorders to mice with blunted reward restores social abilities

(2018) Camille N. Pujol et al.   Translational Psychiatry

A Neural Circuit for Gut-Induced Reward

(2018) Wenfei Han et al.   CELL

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder

(2018) Martina Sgritta et al.   NEURON

Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors

(2018) Sebastian P. Fernandez et al.   Nature Communications

What Is the Male-to-Female Ratio in Autism Spectrum Disorder? A Systematic Review and Meta-Analysis

(2017) Rachel Loomes et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1

(2017) Vaishnav Krishnan et al.   NATURE

Gating of social reward by oxytocin in the ventral tegmental area

(2017) Lin W. Hung et al.   SCIENCE

Analysis of Microbiome Data in the Presence of Excess Zeros

(2017) Abhishek Kaul et al.   Frontiers in Microbiology

Normalization and microbial differential abundance strategies depend upon data characteristics

(2017) Sophie Weiss et al.   Microbiome

Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism

(2017) Anna V. Golubeva et al.   EBioMedicine

Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol

(2016) Jérôme A.J. Becker et al.   ADDICTION BIOLOGY

Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder

(2016) Hyopil Kim et al.   Behavioral and Brain Functions

Mice Lacking GPR88 Show Motor Deficit, Improved Spatial Learning, and Low Anxiety Reversed by Delta Opioid Antagonist

(2016) Aura C. Meirsman et al.   BIOLOGICAL PSYCHIATRY

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Current knowledge on the genetics of autism and propositions for future research

(2016) Thomas Bourgeron   COMPTES RENDUS BIOLOGIES

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

(2016) Yuta Katayama et al.   NATURE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

SHANK3 controls maturation of social reward circuits in the VTA

(2016) Sebastiano Bariselli et al.   NATURE NEUROSCIENCE

Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity

(2016) Sebastian P Fernandez et al.   NEUROPSYCHOPHARMACOLOGY

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota

(2016) Ilias Lagkouvardos et al.   Nature Microbiology

Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology

(2015) Binta Diémé et al.   JOURNAL OF PROTEOME RESEARCH

A catalog of the mouse gut metagenome

(2015) Liang Xiao et al.   NATURE BIOTECHNOLOGY

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Compact graphical representation of phylogenetic data and metadata with GraPhlAn

(2015) Francesco Asnicar et al.   PeerJ

Urinaryp-cresol is elevated in young French children with autism spectrum disorder: a replication study

(2014) Stefano Gabriele et al.   BIOMARKERS

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

(2014) Madhukumar Venkatesh et al.   IMMUNITY

Autistic-Like Syndrome in Mu Opioid Receptor Null Mice is Relieved by Facilitated mGluR4 Activity

(2014) Jérôme AJ Becker et al.   NEUROPSYCHOPHARMACOLOGY

Dopamine and reward seeking: the role of ventral tegmental area

(2014) Robert Ranaldi   REVIEWS IN THE NEUROSCIENCES

GC-MS-based urine metabolic profiling of autism spectrum disorders

(2013) Patrick Emond et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Altered gut microbiota and activity in a murine model of autism spectrum disorders

(2013) Caroline G.M. de Theije et al.   BRAIN BEHAVIOR AND IMMUNITY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Autism

(2013) Meng-Chuan Lai et al.   LANCET

aLeaves facilitates on-demand exploration of metazoan gene family trees on MAFFT sequence alignment server with enhanced interactivity

(2013) Shigehiro Kuraku et al.   NUCLEIC ACIDS RESEARCH

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

(2013) Paul J. McMurdie et al.   PLoS One

Fecal Microbiota and Metabolome of Children with Autism and Pervasive Developmental Disorder Not Otherwise Specified

(2013) Maria De Angelis et al.   PLoS One

Gastrointestinal Dysfunction in Autism: Parental Report, Clinical Evaluation, and Associated Factors

(2012) Phillip Gorrindo et al.   Autism Research

Urinary p-cresol in autism spectrum disorder

(2012) Antonio M. Persico et al.   NEUROTOXICOLOGY AND TERATOLOGY

Are you or aren’t you? Challenges associated with physiologically identifying dopamine neurons

(2012) Mark A. Ungless et al.   TRENDS IN NEUROSCIENCES

Urinaryp-cresol is elevated in small children with severe autism spectrum disorder

(2011) Laura Altieri et al.   BIOMARKERS

Warning: the unfortunate end of p-cresol as a uraemic toxin

(2011) R. Vanholder et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Derivatization reagents in liquid chromatography/electrospray ionization tandem mass spectrometry

(2010) Tomofumi Santa   BIOMEDICAL CHROMATOGRAPHY

Urinary Metabolic Phenotyping Differentiates Children with Autism from Their Unaffected Siblings and Age-Matched Controls

(2010) Ivan K. S. Yap et al.   JOURNAL OF PROTEOME RESEARCH

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Metabolite analysis of human fecal water by gas chromatography/mass spectrometry with ethyl chloroformate derivatization

(2009) Xianfu Gao et al.   ANALYTICAL BIOCHEMISTRY

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Catalytic Activity of the Anaerobic Tyrosine Lyase Required for Thiamine Biosynthesis in Escherichia coli

(2009) Martin R. Challand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix

(2009) M. N. Price et al.   MOLECULAR BIOLOGY AND EVOLUTION

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice

(2009) David Delotterie et al.   PSYCHOPHARMACOLOGY

Effects of dopamine D4 receptor antagonist on spontaneous alternation in rats

(2008) Anette Moustgaard et al.   Behavioral and Brain Functions