Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol

Commonalities and Distinctions Among Mechanisms of Addiction to Alcohol and Other Drugs

(2015) Angela R. Ozburn et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Effects of ethanol exposure and withdrawal on dendritic morphology and spine density in the nucleus accumbens core and shell

(2015) Veronica L. Peterson et al.   BRAIN RESEARCH

Dorsal raphe 5-HT2C receptor and GABA networks regulate anxiety produced by cocaine withdrawal

(2015) Caryne P. Craige et al.   NEUROPHARMACOLOGY

Adolescent nicotine alters dendritic morphology in the bed nucleus of the stria terminalis

(2015) Kelsey C. Smith et al.   NEUROSCIENCE LETTERS

Differential vulnerability to relapse into heroin versus cocaine-seeking as a function of setting

(2015) Christian Montanari et al.   PSYCHOPHARMACOLOGY

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

(2015) Daniil Sarkisyan et al.   Frontiers in Cellular Neuroscience

Social Cognition Deficits and Associations with Drinking History in Alcoholic Men and Women

(2015) Mary M. Valmas et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Impaired fear recognition and attentional set-shifting is associated with brain structural changes in alcoholic patients

(2014) Leanne Trick et al.   ADDICTION BIOLOGY

Adolescent nicotine-induced dendrite remodeling in the nucleus accumbens is rapid, persistent, and D1-dopamine receptor dependent

(2014) D. G. Ehlinger et al.   Brain Structure & Function

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Modulation of Risky Choices in Recently Abstinent Dependent Cocaine Users: A Transcranial Direct-Current Stimulation Study

(2014) Alessandra Gorini et al.   Frontiers in Human Neuroscience

Cocaine Dysregulates Opioid Gating of GABA Neurotransmission in the Ventral Pallidum

(2014) Yonatan M. Kupchik et al.   JOURNAL OF NEUROSCIENCE

Distinct Mu, Delta and Kappa Opioid Receptor Mechanisms Underlie Low Sociability and Depressive-Like Behaviors During Heroin Abstinence

(2014) Pierre-Eric Lutz et al.   NEUROPSYCHOPHARMACOLOGY

Autistic-Like Syndrome in Mu Opioid Receptor Null Mice is Relieved by Facilitated mGluR4 Activity

(2014) Jérôme AJ Becker et al.   NEUROPSYCHOPHARMACOLOGY

Hostility and Cigarette Use: A Comparison Between Smokers and Nonsmokers in a Matched Sample of Adolescents

(2014) M. H. Bernstein et al.   NICOTINE & TOBACCO RESEARCH

Functional changes of the reward system underlie blunted response to social gaze in cocaine users

(2014) K. H. Preller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced dopamine release in the nucleus accumbens core of adult rats following adolescent binge alcohol exposure: age and dose-dependent analysis

(2014) Shannon L. Zandy et al.   PSYCHOPHARMACOLOGY

Dissociation of heroin-induced emotional dysfunction from psychomotor activation and physical dependence among inbred mouse strains

(2014) G. Ayranci et al.   PSYCHOPHARMACOLOGY

The “addicted” spine

(2014) Saturnino Spiga et al.   Frontiers in Neuroanatomy

Extended access to nicotine leads to a CRF1receptor dependent increase in anxiety-like behavior and hyperalgesia in rats

(2013) Ami Cohen et al.   ADDICTION BIOLOGY

Protracted withdrawal from ethanol and enhanced responsiveness stress: Regulation via the dynorphin/kappa opioid receptor system

(2013) Kelli Gillett et al.   ALCOHOL

A history of chronic morphine exposure during adolescence increases despair-like behaviour and strain-dependently promotes sociability in abstinent adult mice

(2013) P.E. Lutz et al.   BEHAVIOURAL BRAIN RESEARCH

Ethopharmacological analysis of the open elevated plus-maze in mice

(2013) Tatiani Sorregotti et al.   BEHAVIOURAL BRAIN RESEARCH

 FosB Induction in Striatal Medium Spiny Neuron Subtypes in Response to Chronic Pharmacological, Emotional, and Optogenetic Stimuli

(2013) M. K. Lobo et al.   JOURNAL OF NEUROSCIENCE

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

(2013) Gül Dölen et al.   NATURE

Extinction of drug seeking: Neural circuits and approaches to augmentation

(2013) Gavan P. McNally   NEUROPHARMACOLOGY

Addiction as a stress surfeit disorder

(2013) George F. Koob et al.   NEUROPHARMACOLOGY

Addiction science: Uncovering neurobiological complexity

(2013) N.D. Volkow et al.   NEUROPHARMACOLOGY

The Oxytocin Analogue Carbetocin Prevents Emotional Impairment and Stress-Induced Reinstatement of Opioid-Seeking in Morphine-Abstinent Mice

(2013) Panos Zanos et al.   NEUROPSYCHOPHARMACOLOGY

Impaired Hippocampus-Dependent and Facilitated Striatum-Dependent Behaviors in Mice Lacking the Delta Opioid Receptor

(2013) Julie Le Merrer et al.   NEUROPSYCHOPHARMACOLOGY

The Development and Maintenance of Drug Addiction

(2013) Roy A Wise et al.   NEUROPSYCHOPHARMACOLOGY

Deficits in social perception in opioid maintenance patients, abstinent opioid users and non-opioid users

(2012) Skye McDonald et al.   ADDICTION

Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors

(2012) Edward H. Nieh et al.   BRAIN RESEARCH

Nicotine-induced anxiety-like behavior in a rat model of the novelty-seeking phenotype is associated with long-lasting neuropeptidergic and neuroplastic adaptations in the amygdala: Effects of the cannabinoid receptor 1 antagonist AM251

(2012) Cigdem Aydin et al.   NEUROPHARMACOLOGY

Nucleus accumbens D2- and D1-receptor expressing medium spiny neurons are selectively activated by morphine withdrawal and acute morphine, respectively

(2012) T. Enoksson et al.   NEUROPHARMACOLOGY

Neuropsychological consequences of chronic opioid use: A quantitative review and meta-analysis

(2012) A. Baldacchino et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Enhanced Anxiety Observed in Cocaine Withdrawn Rats Is Associated with Altered Reactivity of the Dorsomedial Prefrontal Cortex

(2012) Cynthia El Hage et al.   PLoS One

Protracted abstinence from distinct drugs of abuse shows regulation of a common gene network

(2011) Julie Le Merrer et al.   ADDICTION BIOLOGY

Activation of Brain NOP Receptors Attenuates Acute and Protracted Alcohol Withdrawal Symptoms in the Rat

(2011) Daina Economidou et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Cocaine-Induced Plasticity in the Nucleus Accumbens Is Cell Specific and Develops without Prolonged Withdrawal

(2011) A. Dobi et al.   JOURNAL OF NEUROSCIENCE

Opiate versus psychostimulant addiction: the differences do matter

(2011) Aldo Badiani et al.   NATURE REVIEWS NEUROSCIENCE

Drug-Evoked Synaptic Plasticity in Addiction: From Molecular Changes to Circuit Remodeling

(2011) Christian Lüscher et al.   NEURON

Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition

(2011) Andrea Cippitelli et al.   PLoS One

Neurobiology of the incubation of drug craving

(2011) Charles L. Pickens et al.   TRENDS IN NEUROSCIENCES

Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit

(2010) Nora D. Volkow et al.   BIOESSAYS

Impaired Emotional-Like Behavior and Serotonergic Function During Protracted Abstinence from Chronic Morphine

(2010) Celia Goeldner et al.   BIOLOGICAL PSYCHIATRY

Substance abuse and movement disorders

(2010) John C.M. Brust   MOVEMENT DISORDERS

The pleasures of play: pharmacological insights into social reward mechanisms

(2010) Viviana Trezza et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ambience and Drug Choice: Cocaine- and Heroin-Taking as a Function of Environmental Context in Humans and Rats

(2009) Daniele Caprioli et al.   BIOLOGICAL PSYCHIATRY

Reduced emotional and corticosterone responses to stress in μ-opioid receptor knockout mice

(2009) Soichiro Ide et al.   NEUROPHARMACOLOGY

Reward Processing by the Opioid System in the Brain

(2009) Julie Le Merrer et al.   PHYSIOLOGICAL REVIEWS

Time-Dependent Neuroendocrine Alterations and Drug Craving during the First Month of Abstinence in Heroin Addicts

(2009) Jie Shi et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long-term adverse consequences of drug use?

(2008) I S McGregor et al.   BRITISH JOURNAL OF PHARMACOLOGY

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

Cocaine addiction: From habits to stereotypical-repetitive behaviors and punding

(2008) Alfonso Fasano et al.   DRUG AND ALCOHOL DEPENDENCE

The Role of Amygdalar Mu-Opioid Receptors in Anxiety-Related Responses in Two Rat Models

(2008) Marlene A Wilson et al.   NEUROPSYCHOPHARMACOLOGY

Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat

(2007) Shane A. Perrine et al.   NEUROPHARMACOLOGY