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Title
Orlistat induces ferroptosis-like cell death of lung cancer cells
Authors
Keywords
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Journal
Frontiers of Medicine
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-04
DOI
10.1007/s11684-020-0804-7
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- (2019) ALEKSANDRA CZUMAJ et al. ANTICANCER RESEARCH
- Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling
- (2019) Jiao Wu et al. NATURE
- Fatty acid synthase inhibitor orlistat impairs cell growth and down-regulates PD-L1 expression of a human T-cell leukemia line
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- The antimetastatic activity of orlistat is accompanied by an antitumoral immune response in mouse melanoma
- (2019) Luciana Y. de Almeida et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer
- (2018) Azhar Ali et al. EMBO Molecular Medicine
- Orlistat as a FASN inhibitor and multitargeted agent for cancer therapy
- (2018) Alejandro Schcolnik-Cabrera et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer
- (2018) Anju Singh et al. FASEB JOURNAL
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- An 11‐gene‐based prognostic signature for uveal melanoma metastasis based on gene expression and DNA methylation profile
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- Orlistat treatment induces apoptosis and arrests cell cycle in HSC-3 oral cancer cells
- (2017) Xia Xiao et al. MICROBIAL PATHOGENESIS
- Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma
- (2017) Arvin M. Gouw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increased HAGLR expression promotes non–small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis
- (2017) Chunwei Lu et al. TUMOR BIOLOGY
- Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine
- (2017) Ioannis Poursaitidis et al. Cell Reports
- Recent advances in targeting the fatty acid biosynthetic pathway using fatty acid synthase inhibitors
- (2016) Thelma S. Angeles et al. Expert Opinion on Drug Discovery
- Regulation of Ferroptotic Cancer Cell Death by GPX4
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