SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects

Lack of Evidence of ACE2 Expression and Replicative Infection by SARSCoV-2 in Human Endothelial Cells

(2021) Ian R. McCracken et al.   CIRCULATION

Neuroinvasion of SARS-CoV-2 in human and mouse brain

(2021) Eric Song et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential neurovirulence of Usutu virus lineages in mice and neuronal cells

(2021) Marion Clé et al.   Journal of Neuroinflammation

Interactions of SARS-CoV-2 with the Blood–Brain Barrier

(2021) Michelle A. Erickson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Infection Mechanism of SARS-COV-2 and Its Implication on the Nervous System

(2021) Edwin Estefan Reza-Zaldívar et al.   Frontiers in Immunology

Role of host factors in SARS-CoV-2 entry

(2021) John P. Evans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age

(2020) Katarzyna Bilinska et al.   ACS Chemical Neuroscience

Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction, and Proposed Neurotropic Mechanisms

(2020) Abdul Mannan Baig et al.   ACS Chemical Neuroscience

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Does SARS‐Cov‐2 invade the brain? Translational lessons from animal models

(2020) S. Natoli et al.   EUROPEAN JOURNAL OF NEUROLOGY

A first case of meningitis/encephalitis associated with SARS-Coronavirus-2

(2020) Takeshi Moriguchi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

(2020) Behnood Bikdeli et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence?

(2020) Hua Zhao et al.   LANCET NEUROLOGY

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Involvement of the Nervous System in SARS-CoV-2 Infection

(2020) Hao Li et al.   NEUROTOXICITY RESEARCH

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features

(2020) Neo Poyiadji et al.   RADIOLOGY

Study of Usutu virus neuropathogenicity in mice and human cellular models

(2020) Marion Clé et al.   PLoS Neglected Tropical Diseases

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation

(2020) Duraisamy Kempuraj et al.   NEUROSCIENTIST

Neuropathological Features of Covid-19

(2020) Isaac H. Solomon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier

(2020) Marion Clé et al.   mBio

Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study

(2020) George Goshua et al.   Lancet Haematology

Vasculopathy and Coagulopathy Associated with SARS-CoV-2 Infection

(2020) Nazzarena Labò et al.   Cells

Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells

(2020) Marjolein Heymans et al.   Fluids and Barriers of the CNS

Effects of COVID-19 on the Nervous System

(2020) Costantino Iadecola et al.   CELL

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium

(2020) Fadi Jacob et al.   Cell Stem Cell

SARS ‐CoV‐2 targets neurons of 3D human brain organoids

(2020) Anand Ramani et al.   EMBO JOURNAL

COVID-19 is, in the end, an endothelial disease

(2020) Peter Libby et al.   EUROPEAN HEART JOURNAL

Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection

(2020) Iván Alquisiras-Burgos et al.   MOLECULAR NEUROBIOLOGY

Experimental Models for the Study of Central Nervous System Infection by SARS-CoV-2

(2020) Inmaculada Sanclemente-Alaman et al.   Frontiers in Immunology

The potential role of microvascular pathology in the neurological manifestations of coronavirus infection

(2020) M. A. MacLean et al.   Fluids and Barriers of the CNS

The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

(2020) Elizabeth M. Rhea et al.   NATURE NEUROSCIENCE

The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

(2020) Tetyana P. Buzhdygan et al.   NEUROBIOLOGY OF DISEASE

Pathways Exploited by Flaviviruses to Counteract the Blood-Brain Barrier and Invade the Central Nervous System

(2019) Yasmin Mucunã Mustafá et al.   Frontiers in Microbiology

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation

(2019) Isabella Wimmer et al.   Frontiers in Immunology

Axonal Transport Enables Neuron-to-Neuron propagation of HCoV-OC43

(2018) Mathieu Dubé et al.   JOURNAL OF VIROLOGY

IP-10 Promotes Blood–Brain Barrier Damage by Inducing Tumor Necrosis Factor Alpha Production in Japanese Encephalitis

(2018) Ke Wang et al.   Frontiers in Immunology

Neurological Complications during Treatment of Middle East Respiratory Syndrome

(2017) Jee-Eun Kim et al.   Journal of Clinical Neurology

Mechanisms of restriction of viral neuroinvasion at the blood–brain barrier

(2016) Jonathan J Miner et al.   CURRENT OPINION IN IMMUNOLOGY

ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood–brain barrier

(2016) Ruth Lyck et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes

(2015) Pietra Candela et al.   BRAIN RESEARCH

A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

(2014) Romeo Cecchelli et al.   PLoS One

Human coronaviruses: Viral and cellular factors involved in neuroinvasiveness and neuropathogenesis

(2014) Marc Desforges et al.   VIRUS RESEARCH

Effects of Interleukin-6 on the Expression of Tight Junction Proteins in Isolated Cerebral Microvessels from Yearling and Adult Sheep

(2013) Susan S. Cohen et al.   NEUROIMMUNOMODULATION

Monocytes, viruses and metaphors

(2012) Jonathan W. Yewdell et al.   CELL CYCLE

Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

(2012) Yukio Takeshita et al.   IMMUNOLOGICAL REVIEWS

West Nile virus-induced disruption of the blood-brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

(2012) K. Roe et al.   JOURNAL OF GENERAL VIROLOGY

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

(2010) D. Frommhold et al.   BLOOD

A hitchhiker's guide to the nervous system: the complex journey of viruses and toxins

(2010) Sara Salinas et al.   NATURE REVIEWS MICROBIOLOGY

ICAM-1 Participates in the Entry of West Nile Virus into the Central Nervous System

(2008) J. Dai et al.   JOURNAL OF VIROLOGY