Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes

The emerging role of cellular senescence in renal diseases

(2020) Bingru Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases

(2020) Miguel Fontecha-Barriuso et al.   Biomolecules

Albuminuria Downregulation of the Anti-Aging Factor Klotho: The Missing Link Potentially Explaining the Association of Pathological Albuminuria with Premature Death

(2020) Beatriz Fernández-Fernández et al.   ADVANCES IN THERAPY

Targeting the progression of chronic kidney disease

(2020) Marta Ruiz-Ortega et al.   Nature Reviews Nephrology

From quail to earthquakes and human conflict: a historical perspective of rhabdomyolysis

(2020) Mirna Aleckovic-Halilovic et al.   Clinical Kidney Journal

Ferroptosis and kidney disease

(2020) Diego Martin-Sanchez et al.   NEFROLOGIA

Molecular Mechanisms of AKI in the Elderly: From Animal Models to Therapeutic Intervention

(2020) Barbara Infante et al.   Journal of Clinical Medicine

Senescence and the Aging Immune System as Major Drivers of Chronic Kidney Disease

(2020) Johannes Schroth et al.   Frontiers in Cell and Developmental Biology

PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

(2019) Miguel Fontecha‐Barriuso et al.   JOURNAL OF PATHOLOGY

Contrast-Associated Acute Kidney Injury

(2019) Roxana Mehran et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular Senescence and the Kidney: Potential Therapeutic Targets and Tools

(2019) Sebastian N. Knoppert et al.   Frontiers in Pharmacology

Immunology of the ageing kidney

(2019) Yuki Sato et al.   Nature Reviews Nephrology

Circulating kidney injury molecule‐1 as a biomarker of renal parameters in diabetic kidney disease

(2019) Tomohito Gohda et al.   Journal of Diabetes Investigation

The association of socioeconomic status with incidence and outcomes of acute kidney injury

(2019) Hilda O Hounkpatin et al.   Clinical Kidney Journal

Klotho, the elusive kidney-derived anti-ageing factor

(2019) Maria Dolores Sanchez-Niño et al.   Clinical Kidney Journal

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis

(2019) Takayuki Koyano et al.   Scientific Reports

The potential role of necroptosis in inflammaging and aging

(2019) Gordon H. Royce et al.   GeroScience

Assessing the accuracy of ICD-10 coding for measuring rates of and mortality from acute kidney injury and the impact of electronic alerts: an observational cohort study

(2019) Rachael Logan et al.   Clinical Kidney Journal

Development and internal validation of a prediction model for hospital-acquired acute kidney injury

(2019) Catalina Martin-Cleary et al.   Clinical Kidney Journal

Impact of aging on transition of acute kidney injury to chronic kidney disease

(2019) Myung-Gyu Kim et al.   Scientific Reports

Acute Kidney Injury as a Condition of Renal Senescence

(2018) Lucia Andrade et al.   CELL TRANSPLANTATION

Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice

(2018) Sathyaseelan S. Deepa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel acute kidney injury biomarkers: their characteristics, utility and concerns

(2018) Braian M. Beker et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

Targeting of regulated necrosis in kidney disease

(2018) Diego Martin-Sanchez et al.   NEFROLOGIA

Albumin downregulates Klotho in tubular cells

(2018) Beatriz Fernandez-Fernandez et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

TWEAK and RIPK1 mediate a second wave of cell death during AKI

(2018) Diego Martin-Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines

(2018) Irene Maeve Rea et al.   Frontiers in Immunology

RIPK3-MLKL-mediated necroinflammation contributes to AKI progression to CKD

(2018) Hui Chen et al.   Cell Death & Disease

Biomarkers of drug-induced kidney toxicity

(2018) Benjamin R. Griffin et al.   THERAPEUTIC DRUG MONITORING

Breast Regression Protein–39/Chitinase 3–Like 1 Promotes Renal Fibrosis after Kidney InjuryviaActivation of Myofibroblasts

(2017) Tinika A. Montgomery et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of Reticulon-1A–Mediated Endoplasmic Reticulum Stress in Early AKI Attenuates Renal Fibrosis Development

(2017) Ying Fan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome

(2017) Julia Günther et al.   KIDNEY INTERNATIONAL

Cellular senescence in the aging and diseased kidney

(2017) F. A. Valentijn et al.   Journal of Cell Communication and Signaling

Cellular Senescence: A Translational Perspective

(2017) James L. Kirkland et al.   EBioMedicine

Necroptosis and Inflammation

(2016) Kim Newton et al.   Annual Review of Biochemistry

Renal Aging: Causes and Consequences

(2016) Eoin D. O’Sullivan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

(2016) Diego Martin-Sanchez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

How Kidney Cell Death Induces Renal Necroinflammation

(2016) Shrikant R. Mulay et al.   SEMINARS IN NEPHROLOGY

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

(2016) Reut Yosef et al.   Nature Communications

Aging increases the susceptibility of cisplatin-induced nephrotoxicity

(2015) Jiagen Wen et al.   AGE

Senescence from G2 arrest, revisited

(2015) Véronique Gire et al.   CELL CYCLE

Predictors of Recurrent AKI

(2015) E. D. Siew et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Role for Tubular Necroptosis in Cisplatin-Induced AKI

(2015) Y. Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Necroinflammation in Kidney Disease

(2015) S. R. Mulay et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression

(2015) M. A. Venkatachalam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps

(2015) H. Rabb et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Aging-related inflammation in osteoarthritis

(2015) M.A. Greene et al.   OSTEOARTHRITIS AND CARTILAGE

Macrophages in Kidney Injury, Inflammation, and Fibrosis

(2015) Qi Cao et al.   PHYSIOLOGY

Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”

(2014) Marcello Pinti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Maladaptive Proximal Tubule Repair: Cell Cycle Arrest

(2014) Joseph V. Bonventre   NEPHRON CLINICAL PRACTICE

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dietary restriction attenuates the accelerated aging phenotype of Sod1−/− mice

(2013) Yiqiang Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

(2013) Albert R. Davalos et al.   JOURNAL OF CELL BIOLOGY

Causes, consequences, and reversal of immune system aging

(2013) Encarnacion Montecino-Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Klotho to Treat Kidney Fibrosis

(2013) M. D. Sanchez-Nino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The cyclin-dependent kinase inhibitor p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia/reperfusion injury in mice

(2013) Satoshi Nishioka et al.   KIDNEY INTERNATIONAL

The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response

(2013) Raquel Rodrigues-Díez et al.   LABORATORY INVESTIGATION

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

Understanding immunosenescence to improve responses to vaccines

(2013) Jörg J Goronzy et al.   NATURE IMMUNOLOGY

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

(2013) A. Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severity of sepsis-induced acute kidney injury in a novel mouse model is age dependent*

(2012) Bert Maddens et al.   CRITICAL CARE MEDICINE

Klotho modulates the stress response in human senescent endothelial cells

(2012) Julia Carracedo et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Klotho, phosphate and inflammation/ageing in chronic kidney disease

(2012) M. C. Izquierdo et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Inflammatory Cytokines TWEAK and TNF  Reduce Renal Klotho Expression through NF B

(2011) J. A. Moreno et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chemokines in Renal Injury

(2011) A. C. K. Chung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Immunosenescence: what does it mean to health outcomes in older adults?

(2009) Janet E McElhaney et al.   CURRENT OPINION IN IMMUNOLOGY

Cellular senescence in pretransplant renal biopsies predicts postoperative organ function

(2008) Liane M. McGlynn et al.   AGING CELL

Mechanisms of Renal Apoptosis in Health and Disease

(2008) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY