Genetic Overlap Between Alzheimer’s Disease and Depression Mapped Onto the Brain

Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model

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Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder

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ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

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Delineating the Genetic Component of Gene Expression in Major Depression

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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

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Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

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Discovery of shared genomic loci using the conditional false discovery rate approach

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Automated Detection of Alzheimer’s Disease Using Brain MRI Images– A Study with Various Feature Extraction Techniques

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Quantitative assessment of structural image quality

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Analysis of shared heritability in common disorders of the brain

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Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms

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The UK Biobank resource with deep phenotyping and genomic data

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Assessing the presence of shared genetic architecture between Alzheimer’s disease and major depressive disorder using genome-wide association data

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In Vivo Structural Neuroanatomy of Corpus Callosum in Alzheimer's Disease and Mild Cognitive Impairment Using Different MRI Techniques: A Review

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What we know about TMEM106B in neurodegeneration

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Shared Genetic Risk Factors for Late-Life Depression and Alzheimer’s Disease

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Multimodal population brain imaging in the UK Biobank prospective epidemiological study

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Depression and Incident Alzheimer Disease: The Impact of Disease Severity

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Polygenic dissection of major depression clinical heterogeneity

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A novel Alzheimer disease locus located near the gene encoding tau protein

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An atlas of genetic correlations across human diseases and traits

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UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

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TMEM106B Influences Volume of Left-Sided Temporal Lobe and Interhemispheric Structures in the General Population

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Structural brain changes associated with depressive symptoms in the elderly with Alzheimer's disease

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TMEM106B expression is reduced in Alzheimer’s disease brains

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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Midlife vs Late-Life Depressive Symptoms and Risk of Dementia

(2012) Kristine Yaffe   ARCHIVES OF GENERAL PSYCHIATRY

The Dynamics of Cortical and Hippocampal Atrophy in Alzheimer Disease

(2011) Mert R. Sabuncu   ARCHIVES OF NEUROLOGY

Cross-national epidemiology of DSM-IV major depressive episode

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Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

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History of depression, depressive symptoms, and medial temporal lobe atrophy and the risk of Alzheimer disease

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