Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation and plasma lipids in the Health and Retirement Study.

(2019) Michael W. Lutz et al.   NEUROBIOLOGY OF AGING

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

(2019) Brian W. Kunkle et al.   NATURE GENETICS

Cognitive Deficits in Older Adults With Psychotic Depression: A Meta-Analysis

(2019) Tom Vermeulen et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Using Genetic Instruments to Estimate Interactions in Mendelian Randomization Studies

(2019) Teri-Louise North et al.   EPIDEMIOLOGY

Untangling Genetic Risk for Alzheimer’s Disease

(2018) Anna A. Pimenova et al.   BIOLOGICAL PSYCHIATRY

Improved Use of Small Reference Panels for Conditional and Joint Analysis with GWAS Summary Statistics

(2018) Yangqing Deng et al.   GENETICS

The Progression of Neuropsychiatric Symptoms in Alzheimer’s Disease During a Five-Year Follow-Up: Kuopio ALSOVA Study

(2018) Ilona Hallikainen et al.   JOURNAL OF ALZHEIMERS DISEASE

The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer’s Disease

(2018) Hua Ni et al.   JOURNAL OF ALZHEIMERS DISEASE

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Improved Use of Small Reference Panels for Conditional and Joint Analysis with GWAS Summary Statistics

(2018) Yangqing Deng et al.   GENETICS

Interactions Among Polymorphisms of Susceptibility Loci for Alzheimer’s Disease or Depressive Disorder

(2018) Eva Kitzlerová et al.   MEDICAL SCIENCE MONITOR

GWAS on family history of Alzheimer’s disease

(2018) Riccardo E. Marioni et al.   Translational Psychiatry

Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach

(2017) Xia-Fang Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

(2017) Kuan-lin Huang et al.   NATURE NEUROSCIENCE

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function

(2017) Olav B. Smeland et al.   JAMA Psychiatry

Assessing the presence of shared genetic architecture between Alzheimer’s disease and major depressive disorder using genome-wide association data

(2017) J Gibson et al.   Translational Psychiatry

The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis

(2016) Qing-Fei Zhao et al.   JOURNAL OF AFFECTIVE DISORDERS

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Dissecting the genetics of complex traits using summary association statistics

(2016) Bogdan Pasaniuc et al.   NATURE REVIEWS GENETICS

LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.

(2015) Mitchell J. Machiela et al.   BIOINFORMATICS

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

(2015) R. S. Desikan et al.   CIRCULATION

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Sparse whole-genome sequencing identifies two loci for major depressive disorder

(2015) Na Cai et al.   NATURE

Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms

(2015) Ole A. Andreassen et al.   PLoS One

Identifying Common Genetic Variants in Blood Pressure Due to Polygenic Pleiotropy With Associated Phenotypes

(2014) Ole A. Andreassen et al.   HYPERTENSION

Shared common variants in prostate cancer and blood lipids

(2014) Ole A Andreassen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

(2014) O A Andreassen et al.   MOLECULAR PSYCHIATRY

Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

(2013) B. L. Pierce et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

(2013) Ole A. Andreassen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A practical guide for the functional annotation of genetic variations using SNPnexus

(2013) A. Z. Dayem Ullah et al.   BRIEFINGS IN BIOINFORMATICS

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

(2013) Jimmy Z Liu et al.   NATURE GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-Wide Haplotype Analysis of Cis Expression Quantitative Trait Loci in Monocytes

(2013) Sophie Garnier et al.   PLoS Genetics

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

(2013) Ole A. Andreassen et al.   PLoS Genetics

Neuropsychiatric symptoms in Alzheimer’s disease

(2011) Constantine G. Lyketsos et al.   Alzheimers & Dementia

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Depressive symptoms and risk of dementia: The Framingham Heart Study

(2010) J. S. Saczynski et al.   NEUROLOGY

i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study

(2010) K. Zhang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

SNPnexus: a web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms

(2008) C. Chelala et al.   BIOINFORMATICS